Andrew Steele is a scientist, writer and presenter.
Ageing is a phenomenon we’re all familiar with and is completely taken for granted as a fact of reality, but do we have to accept.
Expect to learn why curing ageing might be easier than curing cancer and all other diseases, the unfortunate truth of fasting for longevity, why the next decade will be the most exciting for lifespan research and much more…
Sponsors:
“I can feel touching my daughter’s hand or touching my wife’s hand, or picking up a hollow eggshell without crushing it,” Anderson says of his work with Psyonic, a startup operating out of the University of Illinois’ Research Park, in Urbana-Champaign. Psyonic expects to provide commercial prostheses with pressure sensing next year, and ones with sensory feedback sometime after that.
Technology is on the threshold of turning the unthinkable into reality. Awkward, unfeeling prostheses are morphing into mind-controlled extensions of the human body that give their wearers a sense of touch and a greater range of motion.
Along with sensory feedback, Psyonic’s rubber and silicone prosthesis uses machine learning to give its wearers intuitive control. The Modular Prosthetic Limb from Johns Hopkins University promises to deliver “humanlike” strength, thought-controlled dexterity and sensation. It’s currently in the research phase. And Icelandic company Ossur is conducting preclinical trials on mind-controlled leg and foot prostheses. These and other advances could make it dramatically easier for amputees to perform the sorts of tasks most people take for granted.
In a new study published in the journal Nature Medicine, individuals with brown fat had lower prevalences of cardiometabolic diseases, and the presence of brown fat was independently correlated with lower odds of type 2 diabetes, dyslipidemia, coronary artery disease, cerebrovascular disease, congestive heart failure and hypertension.
Trip Planning
With their AI approximation for psychedelic trips in place, the team says they can start to probe for similarities with how the human brain processes drugs, citing the structural similarity between neural nets and the human visual cortices.
“The process of generating natural images with deep neural networks can be perturbed in visually similar ways and may offer mechanistic insights into its biological counterpart — in addition to offering a tool to illustrate verbal reports of psychedelic experiences,” Schartner told PsyPost.
Lightweight VTOL Air Ambulances To Be Optimized For Emergency Response
Urban Aeronautics Ltd., a leading Israeli aerospace company, today announced it has reached an agreement to provide four CityHawk VTOL aircraft to Hatzolah Air for emergency medical service (EMS) applications.
In addition, Hatzolah Air will become Urban Aeronautics’ official sales representative and distribution channel to other EMS and rescue organizations worldwide. The companies previously signed an MOU to develop, produce, and market the CityHawk aircraft for EMS applications.
One mouse is hunched over, graying, and barely moves at 7 months old. Others, at 11 months, have sleek black coats and run around. The videos and other results from a new study have inspired hope for treating children born with progeria, a rare, fatal, genetic disease that causes symptoms much like early aging. In mice with a progeria-causing mutation, a cousin of the celebrated genome editor known as CRISPR corrected the DNA mistake, preventing the heart damage typical of the disease, a research team reports today in. Treated mice lived about 500 days, more than twice as long as untreated animals.
“The outcome is incredible,” says gene-therapy researcher Guangping Gao of the University of Massachusetts, who was not involved with the study.
Although the developers of the progeria therapy aim to improve it, they are also taking steps toward testing the current version in affected children, and some other scientists endorse a rush. The mouse results are “beyond anyone’s wildest expectations,” says Fyodor Urnov, a gene-editing researcher at the University of California, Berkeley. “The new data are an imperative to treat a child with progeria … and do so in the next 3 years.”
Summary: Heating up cancer cells as they are being targeted with chemotherapy appears to be a highly effective way of killing them off.
Source: UCL
The study, published in the Journal of Materials Chemistry B, found that “loading” a chemotherapy drug on to tiny magnetic particles that can heat up the cancer cells at the same time as delivering the drug to them was up to 34% more effective at destroying the cancer cells than the chemotherapy drug without added heat.
Has some interesting parts, might interest some.
(not sure how novel)
As human beings age, the functioning of organs gradually deteriorates. While countless past studies have investigated the effects of aging on the human body, brain and on cognition, the neural mechanisms and environmental factors that can accelerate or slow down these effects are not yet fully understood.
The immune system and the nervous system are both known to play a key role in the control of organs in the body. Moreover, past findings suggest that both of these systems change significantly during aging.
