Category: biotech/medical – Page 1,509
Ancient Cave Art in Alabama May Be The Largest Ever Found in North America
New details of our past are coming to light, hiding in the nooks and crannies of the world, as we refine our techniques to go looking for them. Most lauded is the reconstruction of the evolution of humanity since our African origins around 300,000 years ago, by analyzing our living and fossil DNA.
Replete with the ghosts of African and Eurasian populations of the deep past, these have been resurrected only through the ability of science to reach into the world of the minuscule by studying biomolecules.
Now, digital analysis of rock surfaces reveals how other ghosts of the deep past – this time from almost 2,000 years ago in North America – have been coaxed into the light.
Sirtuin 6 : Summary Of Key Points of Professor Cohen Interview | Modern Healthspan
There is a SIRT6 activator on the market but it is very expensive at a few hundred dollars.
We have had requests for a summary of the interview with Prof Cohen. This video is a summary of the key points from the interviews. As I note in the introduction, this is my interpretation of what Prof Cohen said, please check the original interviews if you have any questions. And please do feel free to let me know if you think I got something wrong!
Professor Haim Cohen is the director of the Sagol Healthy Human Longevity Center at Bar-Ilan University where he focuses much of his research on the SIRT6 protein. In May 2021 he and his team published a paper showing a 30% increase in lifespan in a mouse model by over expressing SIRT6.
Prof Cohen’s page at the university.
https://life-sciences.biu.ac.il/en/node/641
Prof Cohen’s Lab.
https://www.haimcohenlab.com/
Prof Cohen’s Paper on Sirt6 is here.
Longevity Research is an Economic Necessity
It is vital to recognize the immediate economic importance of i nvesting in longevity and healthy-aging sciences.
Aging itself is a complex series of at least 300 biological processes involving more than 10% of our genetic makeup. It follows that methods to combat these effects must be a combination of sciences, from biotech to biophysics and pharmaceuticals. There is no single “silver bullet” solution.
Aging, along with the physical and mental decay that accompanies it, is still widely regarded as a natural and inevitable thing. It is not, it is a degenerative disease in which the physical integrity and structure of our cells decay each time they divide to replace old ones or as part of any healing process.
‘Nanomagnetic’ computing can provide low-energy AI, researchers show
Researchers have shown it is possible to perform artificial intelligence using tiny nanomagnets that interact like neurons in the brain.
The new method, developed by a team led by Imperial College London researchers, could slash the energy cost of artificial intelligence (AI), which is currently doubling globally every 3.5 months.
In a paper published today in Nature Nanotechnology, the international team have produced the first proof that networks of nanomagnets can be used to perform AI-like processing. The researchers showed nanomagnets can be used for ‘time-series prediction’ tasks, such as predicting and regulating insulin levels in diabetic patients.
Scientists engineer a bacteria to produce a drug used to treat Parkinson’s disease
The results of the study could lead to new treatment options. In a groundbreaking new study published in the journal Nature on Thursday, researchers have compared the brain cells of patients who had died from either Parkinson’s disease or dementia to people unaffected by the disorders and found which brain cells are responsible for both conditions.
A team of researchers has created a bacteria that can produce a steady and consistent source of medicine inside a patient’s gut, suggesting the possibility for genetically edited bacteria to be an efficient Parkinson’s disease treatment.
Moreover, the researchers have shown via preclinical experiments that the novel treatment technique is not only safe and well-tolerated, but it also reduces side effects that can occur when other treatments are utilized.
An engineered probiotic
For long, scientists have been experimenting with ways of engineering bacteria to fit our needs for decades. The new research is the latest example of that.
Blood Test Analysis: Italian Centenarians
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Biomarker timestamps:
Glucose 1:37
HDL 2:43
Triglycerides 4:10
RBCs, Hemoglobin 5:29
Platelets 7:16
Uric Acid 8:37
AST, ALT 11:04
Total Cholesterol 13:55
WBCs 15:47
Total Protein, Albumin, Globulin 17:38
Creatinine 21:27
BUN 22:35
Papers referenced in the video:
Laboratory parameters in centenarians of Italian ancestry.
https://pubmed.ncbi.nlm.nih.gov/17681733/
Risk Factors For Hyperuricemia In Chinese Centenarians And Near-Centenarians.
https://pubmed.ncbi.nlm.nih.gov/31908434/
Fasting glucose level and all-cause or cause-specific mortality in Korean adults: a nationwide cohort study.
https://pubmed.ncbi.nlm.nih.gov/32623847/
High-density lipoprotein cholesterol and all-cause mortality by sex and age: a prospective cohort study among 15.8 million adults.
Scientists engineer new tools to electronically control gene expression
Researchers, led by experts at Imperial College London, have developed a new method that allows gene expression to be precisely altered by supplying and removing electrons.
This could help control biomedical implants in the body or reactions in large ‘bioreactors’ that produce drugs and other useful compounds. Current stimuli used to initiate such reactions are often unable to penetrate materials or pose risk of toxicity—electricity holds the solution.
Gene expression is the process by which genes are ‘activated’ to produce new molecules and other downstream effects in cells. In organisms, it is regulated by regions of the DNA called promoters. Some promoters, called inducible promoters, can respond to different stimuli, such as light, chemicals and temperature.
Israeli start-up produces artificial vegetarian blood from micro-algae
Bill Rhoads
Yemoja researchers combined Porphyridium algae derivatives after developing a groundbreaking system for the biological culture of pure and standardized components from micro-algae intended for the food and cosmetics industries.