Lifeboat Foundation

I shared about this startup in January, now it’s hitting US Markets. The Israeli startup Sonovia, which sped up efforts to manufacture masks using its anti-pathogen fabric at the start of the coronavirus crisis in Israel, has launched commercial sales.

“When coronavirus started, we were an Israeli startup,” Dr. Jason Migdal, a research scientist with Sonovia, told The Jerusalem Post. “Now, we are a commercial business that is having success internationally.”

Sonovia developed an almost-permanent, ultrasonic, fabric-finishing technology for mechanical impregnation of zinc oxide nanoparticles into textiles.

Continue reading “Israeli masks designed with unique anti-pathogen fabric enter US market” »

As if this contagion movie we are living can not get any more strange. A University of Pittsburgh researcher who claimed to have been on the verge of a significant breakthrough in his research on the coronavirus was killed in what appears to me a murder-suicide…

While police are treating the death as a homicide, they have yet to find any evidence that it was related to his research.

Others believe it is the same Kim saying he only looks different because he has had plastic surgery.

And, to add to the mystery, the claims come as the North Korean leader missed yet another high-profile event.

He was noticeably absent as Russia awarded him a medal to mark the 75th anniversary of the victory over Nazi Germany.

Recent sleep surveys show that Singaporeans are among the world’s most sleep-deprived people. Scientists from Duke-NUS Medical School (Duke-NUS) and the University of Tokyo provide new evidence, which supports the presence of a key mechanism that regulates our biological clock. In the study published in PNAS, the team used preclinical models to validate that mutations in PER2 protein can alter the balance of the circadian period, which can lead to sleep disorders.

Biological clocks are an organism’s innate timing device. It is composed of specific proteins called clock proteins, which interact in cells throughout the body. Biological clocks produce and regulate circadian rhythms —the physical, mental, and behavioral changes that follow a daily cycle. Understanding the molecular mechanisms of the circadian clock provides a huge potential to identify therapeutic interventions to mitigate circadian disruption, and its long-term consequences such as diabetes, obesity and cancer among shift workers, who undergo frequent circadian disruption and are more prone to these diseases.

The Duke-NUS scientists had previously discovered that mutations in a specific protein (called casein kinase 1) alters the core clock protein (called PERIOD or PER), and this changes the timing of the biological clock. In this study, preclinical models were used to investigate the role of PER2 (a type of PER protein) in clock regulation to further understand and strengthen the model.

Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.

The find has implications for drug design, genetics and biomedical research and is described in a study published on April 21, 2020, in the Proceedings of the National Academy of Sciences. To illustrate the biological ramifications, study co-authors Oleg Igoshin, Anatoly Kolomeisky and Joel Mallory of Rice’s Center for Theoretical Biological Physics (CTBP) used three wide-ranging examples: protein folding, enzyme catalysis and motor protein efficiency.

Igoshin said the symmetry “wasn’t that hard to prove, but no one noticed it before.”

Why hasn’t #MachineLearning conquered SARS-CoV-2 that causes COVID-19 (P.S., SARS-CoV-2 is the name of the #virus, while COVID-19 is the name of the disease)? One of the possible answers is that the virus “learns” faster than machines through “mutations”.

That causes us thinking: If mutation is such an efficient weapon (for virus), can we learn something from it and then apply our understanding to #DeepLearning to create “fast-mutating” #DeepLearning models capable of helping us to fight intractable crisis like a #pandemic?

https://bit.ly/3c9GE5s

Continue reading “Mechanisms of viral mutation” »

SAN DIEGO, May 4, 2020 /PRNewswire/ — Global Institute of Stem Cell Therapy and Research (GIOSTAR), the worldwide leader in stem cell research, is pleased to announce that they have received an approval for a COVID-19 clinical trial, led by their Medical Director Dr. Prabhat Soni. GIOSTAR will conduct the trial using stem cells to treat COVID-19 patients, under the approval of the United States Food and Drug Administration (FDA) “expanded access for compassionate use” program. The Institute is exploring a promising alternative approach to the devastating disorder, which leverages the anti-inflammatory properties of mesenchymal stem cells (MSCs). According to Dr. Soni, the investigation is based upon two decades of stem cell research by GIOSTAR Co-Founder, Chairman and Chief Scientific Officer Dr. Anand Srivastava.

Rhesus macaques don’t monkey around when it comes to HIV; they have a protein that effectively disables invading HIV particles.

A group of University of Chicago scientists announced an innovative study that explains how the macaques’ immune protein, called TRIM5α, works its magic. It also represents a significant step forward in the science of modeling how complex biological proteins assemble themselves, the scientists said.

“These proteins work together to encase the HIV capsid in a hexagonal net and restrict viral activity,” said postdoctoral fellow Alvin Yu and lead author of the study, which was published in Nature Communications.

The condition has features of Kawasaki disease, a rare but serious illness first connected to coronavirus in the U.K.