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Category: biotech/medical – Page 1,062
Bio Tech Dominates Research Schedule to Advance Space, Earth Industries
The Expedition 72 crew studied micro-algae and DNA-like nanomaterials on Tuesday to improve health in space and on Earth. The orbital residents also worked on cargo transfers and lab maintenance aboard the International Space Station.
NASA Flight Engineer Nick Hague began his day processing radiation-resistant samples of Arthrospira C micro-algae and stowing them in an incubator for analysis. The samples will be exposed to different light intensities to observe how they affect the micro-algae’s cell growth and oxygen production. Results may advance the development of spacecraft life support systems and fresh food production in space.
Afterward, Hague joined Commander Suni Williams of NASA for a different research session mixing water with samples of messenger RNA, or mRNA, and protein to create DNA-like nanomaterial products inside the Kibo laboratory module’s Life Science Glovebox. Flight Engineer Butch Wilmore then transferred the samples, exposed them to ultrasonic waves, and imaged them with a spectrophotometer to measure the intensity of light at different wavelengths and evaluate the quality of the nanomaterials. The samples will also be returned to Earth for further evaluation. Results may lead to improved therapies for Earth and space health conditions as well as advance the space economy.
DNA to AI: How Evolution Shapes Smarter Algorithms
Summary: A new AI algorithm inspired by the genome’s ability to compress vast information offers insights into brain function and potential tech applications. Researchers found that this algorithm performs tasks like image recognition and video games almost as effectively as fully trained AI networks.
By mimicking how genomes encode complex behaviors with limited data, the model highlights the evolutionary advantage of efficient information compression. The findings suggest new pathways for developing advanced, lightweight AI systems capable of running on smaller devices like smartphones.
Space: A New Frontier for Exploring Stem Cell Therapy
Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease, two Mayo Clinic researchers say. The research analysis by Fay Abdul Ghani and Abba Zubair, M.D., Ph.D., published in NPJ Microgravity, finds microgravity can strengthen the regenerative potential of cells. Dr. Zubair is a laboratory medicine expert and medical director for the Center for Regenerative Biotherapeutics at Mayo Clinic in Florida. Abdul Ghani is a Mayo Clinic research technologist. Microgravity is weightlessness or near-zero gravity.
“Studying stem cells in space has uncovered cell mechanisms that would otherwise be undetected or unknown within the presence of normal gravity,” says Dr. Zubair. “That discovery indicates a broader scientific value to this research, including potential clinical applications.”
Dr. Zubair has launched stem cell experiments from his lab on three different missions to the ISS. His review paper provides data on the scientific question, “Is space the ideal environment for growing large numbers of stem cells?” Another key concern is whether cells grown in space could maintain their strength and function after splashdown on Earth.
Would You Plant a Chip in Your Brain
“Life is incredible.” Here’s how a brain implant changed the life of Jon Nelson, who long suffered from severe depression. Now a patient advocate for startup Motif, he spoke to Emily Chang about the hope of using neurotech to treat mental illnesses.
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Synthetic Genes Engineered to Mimic how Cells Build Tissues and Structures
Advance paves the way for broad applications in medicine and biotech. Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.
The artificial genes can build intracellular structures through a cascading sequence that builds self-assembling structures piece by piece. The approach is similar to building furniture with modular units, much like those found at IKEA. Using the same parts, one can build many different things and it’s easy to take the set apart and reconstruct the parts for something else. The discovery offers a path toward using a suite of simple building blocks that can be programmed to make complex biomolecular materials, such as nanoscale tubes from DNA tiles. The same components can also be programmed to break up the design for different materials.
The research study was recently published in Nature Communications and led by Elisa Franco, a professor of mechanical and aerospace engineering and bioengineering at UCLA Samueli. Daniela Sorrentino, a postdoctoral scholar in Franco’s Dynamic Nucleic Acid Systems lab, is the study’s first author.
Keeping a cell’s nucleolus compact may be key to fighting aging
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were elucidated in yeast, a model organism famous for making bread and beer and yet surprisingly similar to humans on the cellular level.
The study, published Nov. 25 in Nature Aging, may lead to new longevity treatments that could extend human lifespan. It also establishes a mortality timer that reveals how long a cell has left before it dies.
As people get older, they are more likely to develop health conditions, such as cancer, cardiovascular disease and neurodegenerative diseases.
New Method Maps Gene Activity in Living Human Brain
Summary: Researchers have developed a new method to profile gene activity in the living human brain, offering new insights into neurological conditions like epilepsy. By analyzing RNA and DNA collected from electrodes implanted in patients’ brains, the study linked molecular data with electrical recordings of seizures, creating a detailed snapshot of gene activity.
This approach enhances understanding of seizure networks, potentially improving the precision of epilepsy surgeries for patients who don’t respond to medication. Beyond epilepsy, the method could have applications in studying Alzheimer’s, Parkinson’s, and schizophrenia, advancing knowledge of brain disorders at the molecular level.