Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 1,065

Figure promises the first commercially viable general-purpose humanoid robot

Artificial Intelligence (AI) is unarguably the most exciting field in robotics. And humanoid robots, robots resembling the human body in shape, are one of the most popular forms of AI. However, a lot of work, finances, and research are put into making these humanoid robots.

The field is already crowded with a number of companies with interesting projects, such as Boston Dynamics’ Atlas robot and Tesla’s much-hyped Optimus prototype designed to be “general purpose.”

This week, an AI Robotics startup, Figure, has unveiled Figure 1, the world’s first commercially viable general-purpose humanoid robot. The company says this humanoid will have the ability to think, learn, and interact with its environment.

Is reverse aging already possible? Some drugs that could treat aging might already be on the pharmacy shelves

“People on metformin have 30% lower rates of almost every kind of cancer. It delays cognitive decline. Even people with diabetes who are obese and have more disease to start with but are on metformin have lower mortality rates than people without diabetes who aren’t on the drug.”

What he says is born out in numerous studies. Overall, this safe, super-cheap, decades-old drug not only treats diabetes, but it also seems to delay and compress the years of chronic illness associated with the final stage of life and extend what geroscientists call the “healthspan.”

Metformin is just one of many medications, including other old ones and some brand new inventions, that academic researchers and biotech startups are exploring to slow, stop, or perhaps even reverse aging.

Bowel cancer breakthrough as scientists find chemotherapy response could be predicted by existing NHS test

Researchers hope KRAS test can serve renewed function as soon as possible Scientists have found an existing gene test frequently used on the NHS can also shed light on whether a bowel cancer patient will respond positively or negatively to chemotherapy. Researchers from The Institute of Cancer Research, Imperial College London and the Netherlands Cancer Institute have found the KRAS test can have use beyond its current function of predicting how patients will react to cancer drug cetuximab.

New Assessment for Immunotherapy Response Identified

As a survival mechanism, some tumors, particularly many solid tumors, have evolved to express the ligands capable of turning off the immune response. While immune regulation benefits us under normal conditions, any hindrance of the immune response in the presence of cancer can become detrimental. Understanding these biological processes has led to the development of a promising immunotherapeutic modality: the immune checkpoint inhibitor (ICI). ICIs work by blocking the signals that dampen the immune response.

One prominent checkpoint pathway consists of programmed death 1 (PD1), located on immune cells, and programmed death ligand 1 (PD-L1), expressed on tumor cells. The FDA has approved numerous ICIs to block the interaction of PD-1 and PD-L1 for patients with various solid tumors, including skin, lung, and liver cancers.

Predicting the patients most likely to benefit from PD-1/PD-L1 interventions remains a high priority. Depending on the type of cancer, different tests can predict a patient’s likelihood of responding to ICIs. In some cancers, a readout used to access ICI responsiveness is a patient’s tumor mutational burden (TMB), an estimate of how many mutations appear in the cancer genome. However, better predictive models could help identify more patients who could benefit from these therapies.

Tapping into the molecular fountain of youth

At just 40 years old, Kristen Fortney has spent more than half of her life thinking about the science of aging. But why?

“When I get asked this question I usually blame it on reading too much science fiction,” the CEO and co-founder of the clinical-stage biotech BioAge Labs said with a laugh. “My co-founder, Eric Morgen, and I have been talking about aging since high school.”

Molecular atlas of spider silk production could help bring unparalleled material to market

Researchers from Southwest University in China have constructed the entire chromosomal-scale genome assembly and complete spidroin gene set of the golden orb-weaving spider, Trichonephila clavata, known for its especially strong, golden-colored webs.

They attest that their work “Provides multidimensional data that significantly expand the knowledge of spider dragline silk generation…” and the researchers plan on using this new “molecular atlas” to better understand how spiders manufacture their silk.

Published in the journal Nature Communications, the paper details the steps the researchers took, from wild spider capture to multiomic analysis, in revealing the interplay of genes within the spider’s major ampullate gland, the gland responsible for producing dragline silk.

Destroying the superconductivity in a kagome metal

A new RMIT-led international collaboration published in February has uncovered, for the first time, a distinct disorder-driven bosonic superconductor-insulator transition.

The discovery outlines a global picture of the giant anomalous Hall effect and reveals its correlation with the unconventional charge density wave in the AV3Sb5 kagome metal family, with potential applications in future ultra-low energy electronics.

Superconductors, which can transmit electricity without energy dissipation, hold great promise for the development of future low-energy electronics technologies, and are already applied in diverse fields such as hover trains and high-strength magnets (such as medical MRIs).

I Want You To Live to 150… Here’s Why & How

Call it naive, call it crazy, but I think we have a real chance to tackle aging in this century. And though it’s not easy — it’s very simple.

If you have seen the banner of this channel — it says it’s all. But in this video I go deeper into my personal story and motivation. This way I hope you can understand why I’m doing what I’m doing.

So pick your role and let’s work!
Worse case scenario — we’ll live for extra 20 healthy years. Best case… well, well we might stop or reverse aging all together.

Requirements to cure aging:

Aging Cure Requirements /v.0.2

My longevity budget plan for the next several years: (immortality on a budget)

Extending lifespan on a budget.

This channels is designed around the idea that we all have a good chance to live to and past 100 by doing these two things:

Continue reading “I Want You To Live to 150… Here’s Why & How” | >