Epigenetic Leaderboard The Rejuvenation Olympics โ where you win by never crossing the finish line See How You Rank Top 15 largest age reversals validated by phenotypically trained epigenetic methylation algorithms Rank Name % Improved From Baseline Chronological Age Baseline PACE PACE Of Aging Now (Mean Of 3 Tests) Managing Doctor 1 Bryan [โฆ].
๐ ๐๐ซ๐ฎ๐ ๐ญ๐ก๐๐ญ ๐ข๐ง๐๐ซ๐๐๐ฌ๐๐ฌ ๐๐จ๐ฉ๐๐ฆ๐ข๐ง๐ ๐๐๐ง ๐ซ๐๐ฏ๐๐ซ๐ฌ๐ ๐ญ๐ก๐ ๐๐๐๐๐๐ญ๐ฌ ๐จ๐ ๐ข๐ง๐๐ฅ๐๐ฆ๐ฆ๐๐ญ๐ข๐จ๐ง ๐จ๐ง ๐ญ๐ก๐ ๐๐ซ๐๐ข๐ง ๐ข๐ง ๐๐๐ฉ๐ซ๐๐ฌ๐ฌ๐ข๐จ๐ง, ๐๐ฆ๐จ๐ซ๐ฒ ๐ฌ๐ญ๐ฎ๐๐ฒ ๐ฌ๐ก๐จ๐ฐ๐ฌ
๐ผ๐ฃ ๐๐ข๐ค๐ง๐ฎ ๐๐ฃ๐๐ซ๐๐ง๐จ๐๐ฉ๐ฎ ๐จ๐ฉ๐ช๐๐ฎ ๐ฅ๐ช๐๐ก๐๐จ๐๐๐ ๐๐ฃ ๐๐๐ฉ๐ช๐ง๐โ๐จ ๐๐ค๐ก๐๐๐ช๐ก๐๐ง ๐๐จ๐ฎ๐๐๐๐๐ฉ๐ง๐ฎ ๐จ๐๐ค๐ฌ๐จ ๐ก๐๐ซ๐ค๐๐ค๐ฅ๐, ๐ ๐๐ง๐ช๐ ๐ฉ๐๐๐ฉ ๐๐ฃ๐๐ง๐๐๐จ๐๐จ ๐๐ค๐ฅ๐๐ข๐๐ฃ๐ ๐๐ฃ ๐ฉ๐๐ ๐๐ง๐๐๐ฃ, ๐๐๐จ ๐ฅ๐ค๐ฉ๐๐ฃ๐ฉ๐๐๐ก ๐ฉ๐ค ๐ง๐๐ซ๐๐ง๐จ๐ ๐ฉ๐๐ ๐๐๐๐๐๐ฉ๐จ ๐ค๐ ๐๐ฃ๐๐ก๐๐ข๐ข๐๐ฉ๐๐ค๐ฃ ๐ค๐ฃ ๐๐ง๐๐๐ฃ ๐ง๐๐ฌ๐๐ง๐ ๐๐๐ง๐๐ช๐๐ฉ๐ง๐ฎ, ๐ช๐ก๐ฉ๐๐ข๐๐ฉ๐๐ก๐ฎ ๐๐ข๐ฅ๐ง๐ค๐ซ๐๐ฃ๐ ๐จ๐ฎ๐ข๐ฅ๐ฉ๐ค๐ฃ๐จ ๐ค๐ ๐๐๐ฅ๐ง๐๐จ๐จ๐๐ค๐ฃ.
Numerous labs across the world have shown that inflammation causes reduced motivation and anhedonia, a core symptom of depression, by affecting the brainโs reward pathways.
An Emory University study published in Natureโs Molecular Psychiatry shows levodopa, a drug that increases dopamine in the brain, has potential to reverse the effects of inflammation on brain reward circuitry, ultimately improving symptons of depression.
Past research conducted by the Department of Psychiatry and Behavioral Sciences at Emory University School of Medicine has linked the effects of inflammation on the brain to decreased release of dopamine, a chemical neurotransmitter that regulates motivation and motor activity, in the ventral striatum.
I never thought Iโd order live human kidney cells to my address, but that all changed when I found out about biohacker Jo Zaynerโs at-home genetic engineering class.
You may know Jo Zayner, a โbiohackerโ who has been in the vanguard of scientific self-experimentation for years, from their role in Netflixโs 2019 docuseries Unnatural Selection. The series shows Zayner attempting to edit their DNA by injecting themselves with CRISPR, a gene-editing technology. The action inspired a firestorm of criticism.
Zayner is also known for a variety of other bold moves, such as claiming to create a DIY at-home COVID vaccine in 2020 and executing their own fecal microbiome transplant.
Greater diversification could help agriculture withstand climate, economic and geopolitical crises.
โItems in this section have limited availability due to supplier production issues,โ โSorry, temporarily out of stockโ and โSold outโ are all signs that became familiar as recent global upheavals exposed how precarious our food supply is.
The COVID-19 pandemic led to bare shelves in supermarkets as shipping routes were cut off. The war in Ukraine has affected the supply of essential grains.
CRISPR may be in for a fight thanks to this new, faster, safer, AI-powered zinc-finger gene-editing technique.
A new study has developed what the researchers call the โworldโs firstโ simple, modifiable proteins. Called โzinc fingers,โ these special proteins were developed partially through artificial intelligence.
Scientists from the University of Toronto and the NYU Grossman School of Medicine came up with the method, which is expected to speed up the development of gene therapies. This could be a game-changer for how doctors treat DNA mistakes that happen over time. This is partly because our genes change naturally as we age, which makes it inevitable that mistakes will happen. Or, of course, from genetic disorders inherited at birth.
According to the U.S. Centers for Disease Control and Prevention, more than 40% of people living in the U.S. are obese; and 43% of American women over the age of 60โlong past menopauseโare considered obese. A recent Johns Hopkins study showed that a drug first developed to treat Alzheimerโs disease, schizophrenia, and sickle cell disease could treat obesity and fatty liver and improve heart functionโwithout changes in food intake or daily activity.
Posted in biotech/medical, robotics/AI
Researchers from Harvard Medical School found that it is the changes that affect the expression of the DNA โ called epigenetics โ that affect aging. The discovery may pave the way for more insights into how humans age.
Electronic cigarette (e-cigarette) users have greater lung inflammation than cigarette smokers and non-smokers, according to a new study published online in The Journal of Nuclear Medicine. This study is the first to provide evidence that vaping e-liquids with e-cigarettes creates a unique inflammatory response in the lungs that is different from cigarette smoking.
E-cigarette usage has increased dramatically in the past several years, particularly among adolescents and young adults. While many people assume that e-cigarettes are safer than conventional cigarettes, e-cigarettes can cause pulmonary inflammation and increase the risk of lung disease. In addition, their long-term safety has not been rigorously evaluated.
This is the first PET study to use a novel radiotracer, 18 F-NOS, to compare lung inflammation between cigarette and e-cigarette users in vivo. Although PET imaging with 18 F-FDG has been used in the past to investigate inflammation in smokers and vapers, its conclusions were limited.
