Microsoft uncovers a macOS flaw allowing unauthorized access to sensitive data. Update your device now!
Group-IB reveals Cicada3301 ransomware’s affiliate panel, targeting U.S. and U.K. sectors with cross-platform attacks.
RomCom cyber attacks target Ukraine with new SingleCamper RAT, aiming for espionage and ransomware.
Investing in humanoid robotics could revolutionize economies, boosting productivity and prosperity exponentially. Find out why countries should prioritize this game-changing technology.
The world’s largest maker of advanced chips has been one of the biggest beneficiaries of a global race to develop artificial intelligence.
Taiwan Semiconductor Manufacturing Co. shares hit a record high after the chipmaker topped quarterly estimates and raised its target for 2024 revenue growth, allaying concerns about global chip demand and the sustainability of an AI hardware boom.
Henry Ford, the famous American industrialist and founder of the Ford Motor Company, was granted a patent for the construction of a plastic car on January 13th, 1942.
Discover the fascinating story of Henry Ford’s Plastic Hemp Car, an innovative vehicle made from hemp and soybean plastic in the 1940s.
Despite its almost perfect anti-aging profile, rapamycin exerts one significant limitation – inappropriate physicochemical properties. Therefore, we have decided to utilize virtual high-throughput screening and fragment-based design in search of novel mTOR inhibiting scaffolds with suitable physicochemical parameters. Seven lead compounds were selected from the list of obtained hits that were commercially available (4, 5, and 7) or their synthesis was feasible (1, 2, 3, and 6) and evaluated in vitro and subsequently in vivo. Of all these substances, only compound 3 demonstrated a significant cytotoxic, senolytic, and senomorphic effect on normal and cancerous cells. Further, it has been confirmed that compound 3 is a direct mTORC1 inhibitor. Last but not least, compound 3 was found to exhibit anti-SASP activity concurrently being relatively safe within the test of in vivo tolerability. All these outstanding results highlight compound 3 as a scaffold worthy of further investigation.
GRAPHICAL ABSTRACT
My name is Asim, Global Product Marketing Lead for Peridot, and I’m excited to share some news about our Peridot franchise that I’m incredibly passionate about.
Virtual pets have long been a source of fun and entertainment. But what if they could help us recover from injuries and illnesses, too?
Today we’re announcing our partnership with Augment Therapy, a digital health company building accessible immersive exercise software for healthcare. Together, we aim to help people recover from injuries and illnesses faster by creating new Peridot-inspired experiences for physical rehabilitation use cases in pediatric and geriatric care. What makes this partnership truly exceptional is our shared vision: leveraging cutting-edge technology to encourage movement and promote well-being.
Axions—theorized particles that could account for dark matter—could accumulate around rapidly rotating neutron stars to the point that they become detectable.
The prediction that twisted semiconductor bilayers can host so-called non-Abelian states without a magnetic field holds promise for fault-tolerant quantum computing.
