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Bones may release proteins that slow aging and extend life span

Bones may not only shape how a body looks, but also how it ages. Researchers investigating the well-known antiaging effects of physical activity have found in mice that bones may be a veritable fountain of youth, dribbling out proteins that slow aging, keep the body healthy, and extend life span.

The rodent results, published last week in Cell Metabolism, show mechanical strain on the skeleton—the pushing, pulling, and twisting that normally happen during exercise and other forms of physical activity—triggers force-sensing bone cells called osteocytes to secrete the antiaging chemicals. Indeed, the research team could extend mouse lives by nearly 3 months—the equivalent of about nine human years—just by gently squeezing their leg bones.

“Bone is not just a passive scaffold; it is an active, mechanically responsive organ that helps set the pace of aging throughout the body,” says Xiaochun Bai, a leader of the study and a bone biologist at Southern Medical University. “For the first time, we demonstrated the role of bone ‘mechanosensing’ in systemic aging.”

Humans evolved through culture more than biology

Our biology is central to our survival. This is the evolutionary story and one we take to apply to all living beings equally. However, biologist, anthropologist, and UN and WWF consultant, Jonathan Loh, argues that humans are special in a fundamental way. In this article, he proposes the radical new idea that the transmission of cultural characteristics is more important for human survival than biological ones. We pass down our cultural traits using language, which allows us to transcend our ancestry and reach beyond our tribes.

The peculiar primate

By any measure, Homo sapiens is an exceptional species. The world’s 8.3 billion humans collectively weigh around 400 million tonnes, while all wild mammals combined make up only about 60 million tonnes. And if we add domesticated animals to our side of the scales, we plus our domesticates outweigh wild mammals by a factor of 17.

Quantum physics can determine a person’s location

Scientists have demonstrated a quantum technique to ensure that someone is in the location they claim to be, physicist Abigail Gookin reported March 18 at the American Physical Society’s Global Physics Summit. Called quantum position verification, the technique is based on the concept of quantum entanglement, in which the fates of two far-flung particles are closely linked.

Abstract: Equipe Leader Fondation ARC, INSERM U932, Immunity and Cancer, Institut Curie, PSL University, Paris, France

Equipe Leader Fondation ARC, INSERM U932, Immunity and Cancer, Institut Curie, PSL University, Paris, France.

2Surgical Oncology Department, Institut Curie, Paris, France.

3Department of Biostatistics, Centre Lacassagne, Nice, France.

4Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.