NASA’s Nancy Grace Roman Space Telescope is gearing up to unlock the deepest secrets of the universe with three groundbreaking surveys. Designed with input from over a thousand scientists worldwide, Roman’s missions will map billions of galaxies, capture the dynamic dance of cosmic phenomena like
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Strategies to boost antibody selectivity in oncology
Antibodies in oncology are being equipped with toxic cargoes and effector functions that can kill cells at very low concentrations. A key challenge is that most targets on cancer cells are also present on at least some healthy cells. Shared targets can result in off-tumor binding and compromise the safety and potential of therapeutic candidates. In this review, we survey strategies that can help direct biologics to cancer sites more selectively. These strategies are becoming increasingly feasible thanks to advances in molecular design and engineering. The objective is to create therapeutics that exploit changes in cancer and leverage the human body infrastructure, enabling therapeutics that discriminate not just self from non-self but diseased from healthy tissue.
The Hidden Impact: Lingering Brain Injury Symptoms Haunt Concussion Patients
Even mild concussion can cause long-lasting effects to the brain, according to researchers at the University of Cambridge. Using data from a Europe-wide study, the team has shown that for almost a half of all people who receive a knock to the head, there are changes in how regions of the brain commu
How ‘asymmetric alloying’ is creating the next generation of luminescent materials
Metal cluster molecules are discrete compounds containing multiple metal atoms held together by metal–metal and metal–ligand bonding. They serve as excellent candidates for catalysts, biosensors, and even for drug development. Developing atomic-level molecular editing methods for such metal clusters remains an important challenge and represents a promising strategy for expanding their structural and functional diversity. Such approaches can enable structure-specific properties, high near-infrared (NIR) photoluminescence quantum yields, and unique reactivities and electronic structures.
Alloying is a powerful method for achieving this goal. In this regard, a key challenge is asymmetric alloying, which introduces asymmetry into the metal cluster by selectively placing heterometal atoms at nonequivalent sites, desymmetrizing the cluster and therefore imparting chirality-associated functionality.
Moreover, highly selective asymmetric synthesis methods for heterometallic clusters are expected to contribute significantly to the development of chiroptical materials. However, methods capable of achieving such controlled asymmetric synthesis have rarely been reported.
North Atlantic spring storms have grown more common since 1940, analysis reveals
Storm Dave, which swept across northern Europe over the Easter weekend, is an example of what new research from the University of Gothenburg has revealed. Spring storms forming over the North Atlantic have become more common than they were 80 years ago, and this is due to climate change.
In the Northern Hemisphere, storm seasons follow a seasonal cycle. Storms are weakest and least frequent in summer and most intense in winter. As a result of global warming, storm patterns and their course have changed, and several studies have indicated that winter storms appear to be occurring more frequently and with even greater intensity.
Remember when Star Wars and Command & Conquer ruled PC gaming? June in PC Gamer 10, 20, and 30 years ago
Here’s what was happening in PC gaming in June 1996, 2006 and 2016.
Saturn-sized exoplanet with Earth-like temperature reveals methane-rich atmosphere
A planet that is about the size of Saturn, but with a temperature more like Earth’s, has an atmosphere rich in methane, according to a new study using NASA’s James Webb Space Telescope (JWST).
Unlike the gas giant planets—Jupiter and Saturn—in Earth’s solar system, which are distant from the sun and therefore extremely cold, and so-called “hot Jupiters”—giant planets beyond the solar system that are scorching hot due to their proximity to the stars they orbit—the planet is one of only a handful of known temperate, giant planets and the first to have its atmosphere analyzed.
The new details about the composition of the planet’s atmosphere will inform models of planetary formation and evolution and could improve astronomers’ understanding of how Earth’s atmosphere works, according to the research team.
New semiconductor building blocks make power converters smaller, more affordable
Researchers at the Department of Energy’s Oak Ridge National Laboratory incorporated gallium nitride semiconductors to create a high-efficiency power converter that is more compact, affordable, and efficient.
A power converter is a type of device that manages semiconductor switching and transforms current or voltage, so electricity flows smoothly and safely among equipment, power sources, and users.
Silicon semiconductors are the fundamental building blocks of conventional converters. Manufacturer ROHM Semiconductor provided the ORNL research team with gallium nitride semiconductors that enable switching 10 to 20 times faster than silicon while losing less energy in the process.
Glowing Blue Spider Among the Dozens of New Species Discovered in One Area on Research Expedition
A recent expedition to Central Africa has uncovered dozens of new species.
In February, a team of 16 specialists from Africa and around the world visited the Lisima plateau in eastern Angola and conducted a biodiversity survey, through which they discovered dozens of species unknown to science, according to The Wilderness Project, which led the survey.
The organization dedicated to studying and protecting Africa’s freshwater wilderness announced the findings from the remote scientific expedition in the area — seen as one of Africa’s last great biodiversity blank spots — in a news release obtained by PEOPLE on Wednesday, June 3.