Lifeboat Foundation

This study provides new insights into metformin’s effect on the molecular mechanisms inside cells and why it reduces proliferation of cancer cells, emphasising the role of miRNAs in colorectal cancer.

The authors suggest their findings highlight the potential for developing RNA therapeutics for cancer prevention and treatment and possibly for targeted interventions. Although there are several challenges in the field of miRNA therapeutics, this study could signal another step in their development as potential cancer treatments.

Predicting how proteins bind to other molecules could revolutionize biochemistry, drug discovery.

Now, however, astronomers Fan Zou and W. Niel Brandt, both of Penn State University, have led a team that connected the two mechanisms of black-hole growth from observations and simulations. The results may provide some answers at last.

Related: NASA telescope spots ‘cosmic fireworks’ and faint echos from the Milky Way’s supermassive black hole

Continue reading “12 billion years of black hole history, revealed through X-rays and simulations” »

The authors of a new study were able to order all the synthetic genes necessary to reconstruct the 1918 pandemic influenza virus. Do their findings represent a security flaw in a critical area of biotechnology?

Chinese scientists have made a groundbreaking milestone in nuclear fusion. They have announced a major achievement in discovering an advanced magnetic field structure “for the first time in the world” using the Huanliu-3 (HL-3) tokamak, also known as China’s “artificial sun.”

The discovery is the result of the first round of international joint experiments conducted on the HL-3 tokamak, a project that opened to global collaboration at the end of 2023.

A group of researchers have identified at least seven stars that might be surrounded by advanced alien mega-structures known as “dyson spheres.” NBC News’ Ellison Barber speaks with Janna Levin, a professor of physics and astronomy at Barnard College, about the findings and whether the truth is out there.

This is a talk on our recent preprint & database paper A neuroimaging dataset during sequential color qualia similarity judgments with and without reports By Takahiro Hirao, Mitsuhiro Miyamae, Daisuke Matsuyoshi, Ryuto Inoue, Yuhei Takado, Takayuki Obata, Makoto Higuchi, Naotsugu Tsuchiya, Makiko Yamada bioRxiv 2024.05.16.594267; doi: https://doi.org/10.1101/2024.05.16.59…

Most distant spacecraft, #Voyager1, is now returning data from all four science instruments for the first time following a technical issue last November.

NASA’s Voyager 1 spacecraft is conducting normal science operations for the first time following a technical issue that arose in November 2023.

The team partially resolved the issue in April when they prompted the spacecraft to begin returning engineering data, which includes information about the health and status of the spacecraft. On May 19, the mission team executed the second step of that repair process and beamed a command to the spacecraft to begin returning science data. Two of the four science instruments returned to their normal operating modes immediately. Two other instruments required some additional work, but now, all four are returning usable science data.

Continue reading “Voyager 1 Returning Science Data From All Four Instruments” »

Colin Jacobs, PhD, assistant professor in the Department of Medical Imaging at Radboud University Medical Center in Nijmegen, The Netherlands, and Kiran Vaidhya Venkadesh, a second-year PhD candidate with the Diagnostic Image Analysis Group at Radboud University Medical Center discuss their 2021 Radiology study, which used CT images from the National Lung Cancer Screening Trial (NLST) to train a deep learning algorithm to estimate the malignancy risk of lung nodules.