The FCC has approved SpaceX’s application to launch and operate 15,000 next-generation satellites for Starlink Mobile and granted a waiver that lets the company sell satellite wireless service without leasing spectrum from a terrestrial carrier. SpaceX says the constellation will deliver 5G speeds of up to 150Mbps per user.
Microsoft and Nvidia took the stage together at a Windows event in San Francisco on October 8 to unveil the next phase of the personal computer. In a rare joint appearance, the two companies’ CEOs announced a sweeping collaboration spanning operating system security architecture to hardware design, with the goal of making AI agents the core computing entities within the Windows ecosystem.
Nvidia CEO Jensen Huang made clear during the conversation that the personal computer, once a tool for humans, will in the future serve both people and AI agents. He pointed out that agents have the potential to utilize software capabilities far more fully than humans, since users typically only know 10% to 15% of an application’s features, whereas an agent can master every function.
Microsoft CEO Satya Nadella framed the collaboration as a paradigm shift in computing. He noted that when agents begin directly manipulating files, applications, and cloud services, the operating system must be redesigned to allow agents to execute tasks safely and efficiently.
The first fully AI-generated movie is heading to theaters. Is Gods Don’t Give Gifts a bold new frontier for filmmaking — or a troubling sign of things to come?
Games are one of the most creative forms of expression, and the gaming community keeps growing. But game creation has historically been limited to a select group of people who have technical experience and knowledge of complex game engines.
Today, we’re introducing Playground, an experimental gaming platform that lets you create, play, and share custom games. Playground lowers the barriers to creation, so bringing game ideas to life can now be as easy as describing it through a few prompts — no coding experience required.
With Playground’s conversational interface, you can direct the game just by typing what you want to build. Start from a blank canvas, remix starter prompts, or use guided support to shape your concept — and then test it right away. Want to tweak the physics, rewrite the rules, customize the characters, or overhaul the environment? Just ask. You stay in complete control of the creative direction from rough concept to final product.
Technically, OpenAI relies on a library of ready-made components that the model assembles as it writes. Where plain text works better, ChatGPT is supposed to stick with text. Users who don’t want the visuals can switch them off on the web under “Layout and visuals,” though OpenAI says some graphics may still appear. Intelligent UI is rolling out gradually on the web and in updated apps, but not in the Pro thinking mode or the older desktop apps for macOS and Windows.
More Show Than Substance?
Not everyone is convinced. Wired headlined its take by calling Intelligent UI more show than tell. Search Engine Journal points to another consequence: If ChatGPT builds calculators and converters right in the chat, websites offering those tools will lose visitors. It is also unclear how sources will be displayed alongside graphics and comparisons.
Inflammation is one of the immune system’s most important defense responses. It helps the body fight infection and repair damaged tissue. But if that response remains active for too long, it can begin to harm healthy tissue and contribute to conditions including arthritis, heart disease, and diabetes.
Scientists have long known a great deal about how inflammation begins. What has been less clear is how the body decides that the danger has passed and shifts from fighting a threat to repairing the damage.
Neuroblastoma is the most common solid tumor found outside the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children’s Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor’s cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.
The team also created patient-derived models that capture this population, which older laboratory cell lines had missed. The findings, published today in Cancer Cell, give researchers a new framework and a set of tools to study high-risk neuroblastoma.
Neuroblastoma cells are divided into two cell states: adrenergic cells (which are associated with low-risk disease) and mesenchymal cells (which are associated with high-risk disease, treatment resistance and poor outcomes). However, directly identifying cancer-related mesenchymal cells in patient tumors has been challenging because the body also contains healthy mesenchymal cells, which can be mistaken for their malignant counterparts, complicating efforts to study them.