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FINALLY! Starship’s Next Giant Leap

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SpaceX may have just dropped its biggest hint yet about what comes after Starship Flight 13. Indeed, FINALLY! Starship’s Next Giant Leap may be here as the new filings point toward an Orbital Return Demo that could mark the next major milestone on the road to full reusability. With that work continues at Starbase on Pads 1 and 2, the Gigabay, and future launch infrastructure. Elsewhere this week, we cover Falcon 9 launches carrying BlueBird satellites, Starlink, and another classified NRO mission, Cargo Dragon’s return from the International Space Station, Astrobotic’s Griffin lunar lander preparing for launch, Ariane 6’s impressive upgraded debut with its heaviest payload yet, and the dramatic demolition of historic structures at Space Launch Complex 6.

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https://marcus-house.myspreadshop.com/ You can support me on: Patreon — / marcushouse Join my Discord — / discord Follow/Subscribe on Twitter — / marcushouse The production crew: GameplayReviewUK, TiagoCruz, Mr Pleasant, Virtu, Orbitly, Shaun Gisler, Greg Scott, Niall Anderson, ChameleonCircuit Support from these incredible people and groups is massively appreciated: ❤ 📷 Shaun Gisler — https://twitter.com/lifeatstagezero 📷 NASASpaceFlight — / @nasaspaceflight 📷 RGVAerialPhotography — / @rgvaerialphotography 📷 Avid Space — / @labpadre 📷 Greg Scott — / gregscott_photo 📷 Starship Gazer — / starshipgazer ✨ Tony Bela — / infographictony Set models: 😍 Space Rocket Lab’s Starship Models — https://www.spacerocketlab.com/marcus… Mini venting Starship/SLS — https://www.stardesk.co/ 😍 Starship, & Crew Dragon by — https://morethan3d.com/ 😍 Moon/Mars Mova Globes — https://www.movaglobes.com/ 😍 Saturn V — LEGO — https://www.lego.com/en-au/product/le… 😍 Space Shuttle — LEGO — https://www.lego.com/en-au/product/na…
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The production crew:
GameplayReviewUK, TiagoCruz, Mr Pleasant, Virtu, Orbitly, Shaun Gisler, Greg Scott, Niall Anderson, ChameleonCircuit.

Support from these incredible people and groups is massively appreciated: ❤

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The goal is to have at least one Flyover each week. However, Flyovers are dependent on two things.
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Flyover costs include pilot fees, plane rental fees, fuel and more. So, we genuinely appreciate you for not only joining us for these reviews, a perk of being a tiered team member, but also for your generosity!

The RGV Aerial Team greatly appreciate and feel thrilled to have such a supportive space community! THANK YOU FOR YOUR SUPPORT!

AI-designed universal vaccine clears first human trial, targets future coronavirus threats with needle-free delivery

The first human clinical trial of a universal Sarbeco coronavirus vaccine, developed by the University of Cambridge and spin-out DIOSynVax (DVX) Ltd, has shown that the vaccine is safe and has no significant side effects.

The trial, involving 39 healthy volunteers, tested a vaccine designed to provide protection against multiple Sarbeco coronaviruses—the large group of viruses that occur in nature including SARS-CoV-2, which caused the COVID pandemic.

The vaccine triggered immune responses in the volunteers not only to SARS-CoV-2 and SARS, but to related bat viruses that could potentially jump from animals to humans and cause future pandemics.

Memory, agency, and learning in biological and AI systems with Michael Levin and Katrina Schleisman

What if memory isn’t storage at all — but a message from your past self that has to be interpreted?

In this episode, biologist Michael Levin and cognitive neuroscientist Katrina Schleisman join me to take apart one of the most quietly broken ideas in science and AI: that memory works like a hard drive. It doesn’t. And once you see why, a lot of assumptions about minds, machines, and what it means to \.

Massimo (@Rainmaker1973) on X

Scientists have identified a reversal of the long-standing Flynn effect—the roughly 200-year trend of rising average intelligence (measured via IQ and cognitive tests) across generations. For the first time in modern recorded history, Generation Z (born roughly 1997–2012) shows lower performance than previous generations in key cognitive domains, including attention, memory, literacy, numeracy, executive function, problem-solving, and general IQ—despite spending more years in formal education than ever before. Neuroscientist and educator Dr. Jared Cooney Horvath, PhD, MEd, testified before the U.S. Senate Committee on Commerce, Science, and Transportation on January 15, 2026, highlighting this shift. In his written testimony, he stated that cognitive development in children across much of the developed world has stalled or reversed over the past two decades, with declines evident in international assessments (e.g., PISA, TIMSS) and other large-scale data starting around the mid-2000s and accelerating post-2010. Horvath attributes the primary driver not to reduced schooling, but to the widespread integration of digital screens and educational technology (EdTech) in classrooms. He argues that human brains evolved for deep, focused learning through face-to-face interaction and sustained attention, not fragmented skimming or constant task-switching encouraged by devices. Key points from his testimony include: — Teens now spend over half their waking hours on screens, with significant portions in school involving computers or tablets—often leading to off-task behavior and shallower processing. — Evidence from meta-analyses and national/international studies shows a consistent pattern: higher classroom screen exposure correlates with weaker outcomes in reading, math, science, and higher-order reasoning. — Digital tools may aid narrow, repetitive skill practice in controlled settings, but in core academic contexts, they tend to reduce depth of understanding, retention, and critical thinking. Horvath describes this as a “structural mismatch” between human cognition and how digital platforms are designed (to capture and fragment attention), warning that unchecked EdTech adoption risks long-term harm to workforce skills, innovation, and societal reasoning. [Horvath, J. C. (2026). Written testimony before the U.S. Senate Committee on Commerce, Science, and Transportation. U.S. Senate]

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Quantum mechanics theory may work without imaginary numbers, new analysis suggests

Physicists from Heinrich Heine University Düsseldorf (HHU) have examined a fundamental property of quantum mechanics in collaboration with the German Aerospace Center (DLR). In an article published in the journal Physical Review Letters, they show that this theory does not necessarily need to be formulated with imaginary numbers—real numbers can, in fact, also be used.

The physical theory of quantum mechanics describes the world of atomic and subatomic particles. Its development began in the 1900s with physicists such as Max Planck, Niels Bohr, Werner Heisenberg and Erwin Schrödinger.

Quantum mechanics can effectively describe phenomena at microscopic scales, including, for example, the diffraction of particles at a double slit —which shows that particles also exhibit wave-like behavior—and the quantum tunneling effect, in which a certain probability exists that particles can penetrate a barrier even if they have insufficient energy to do so. Particularly important phenomena today include entanglement and coherence, which are key for applications such as quantum computers and communication.

Faster aptamer screening finds synthetic alternatives to antibodies in days instead of months

Aptamers are short DNA or RNA strands that can recognize and bind to a specific target molecule with high precision. Similar to antibodies, they can be used to detect these molecules or modulate their activity. Unlike antibodies, they are much more stable, can be produced synthetically and can be chemically modified to achieve the desired properties. As a result, they can offer capabilities that cannot be achieved with antibodies.

As demand grows for accurate and rapid diagnostic tools, aptamers are often better suited to these applications than antibodies. However, developing aptamers is both experimentally demanding and time-consuming. A team of scientists from IOCB Prague, led by Dr. Marek Ondruš and Prof. Michal Hocek, has now developed a technology that significantly shortens the development process. Their research is published in the journal Nature Communications.

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