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New method brings single-particle quality control to nanocrystal manufacturing

Nanocrystals are already used in millions of devices, including televisions, laptops and displays, and are considered key materials for the next generation of quantum, sensing and solar technologies. However, they have not yet fully realized their potential. One major reason is their inherent heterogeneity: A single solution contains billions of nanocrystals whose properties can differ substantially. Although these particles can be characterized, important quality parameters are typically accessible only as average values across the entire sample.

“For their function in devices, these average values are insufficient,” says Professor Emiliano Cortés, who conducts research at LMU’s Nano-Institute. “Each individual nanoparticle can behave differently—for example, in its size or in how efficiently it emits light, meaning how effectively it converts absorbed energy back into light.”

China supercharges AI with 100-fold faster optical chip breakthrough

A PERSONAL SUPER COMPUTER “MACRO-CHIP” WITH PHOTONIC INTERCONNECTS:

This will soon become possible by the cheap nano-imprinting of hundreds of smaller microchips, without the need for laser lithography, onto a single monolithic wafer, with these chips’ communicating with each other at light speed as a single system via silicon photonics. A team at Peking University has set this race in motion in a major way by developing an optical system to boost AI speeds 100-fold by optical interconnects between individual microchips. The next step will be placing all of those chips onto a single monolithic wafer with a similar communication system between them. Nano-imprinting at large node-scale of 15 or 20 nm will make it possible to mass produce wafer scale systems that combine all the best types of computing features, from logic gates to optical AI accelerators in one compact package on a single wafer. Consumers will not care if the computer chips in their computers are not 14-mm wide 2-nm node chips printed by expensive extreme ultraviolet lithography, but are, instead, 8-inch or 12-inch wide super computer “macro-chips” that give 1,000 times the computing power and speed of the best Nvidia computer on the market today, whereon the distance of the individual chiplets on the wafer from the central optical multiplexer becomes part of the ingrained clock feature of the chip, replacing the traditional clock-time limit. The mother boards, GPUs and CPUs of these systems will all exist on the same wafer and communicate at light speed, with the equivalent of something like 1,000 VRAM of unified memory.

These developments come as the shrinking of traditional silicon microchips is facing a final limit. In the same way that the Personal Computer became the game-changer in the 1980’s, it appears that Personal Super-Computers will become the new kid on the block in the 2030’s.


Peking University researchers develop new all-optical interconnect system linking standard electronic chips with specific algorithms.

Light Can Act as a Quantum Brake to Slow Movement in The Nanoworld, Scientists Discover

The fundamentals of light continue to fascinate scientists and reveal new secrets – including how its effects can be counterintuitive.

Conventional wisdom suggests that light adds energy to heat up particles or set them in motion.

But scientists just caught light doing the opposite: acting as an invisible brake at scales almost too small to imagine.

Inhibiting protein to treat myeloproliferative neoplasms shows preclinical promise

Inhibiting menin, a protein that supports leukemia growth and is already targeted to treat some forms of leukemia, also holds promise for treating myeloproliferative neoplasms. A new study from scientists at St. Jude Children’s Research Hospital showed that inhibiting menin significantly extended survival and reversed multiple disease features in preclinical models. The findings were published today in Cancer Cell.

Menin is best known as a therapeutic vulnerability in certain types of acute leukemia, including those with KMT2A gene rearrangements or NPM1 mutations. Menin inhibitors, such as revumenib, have greatly improved treatment for these cancers and are approved by the Food and Drug Administration (FDA). However, menin inhibition can reduce megakaryocytes (normal platelet-forming cells) and decrease platelet counts. Producing too many megakaryocytes is a hallmark of diseases called myeloproliferative neoplasms, which are slow-developing, rare blood cancers.

John Crispino, Ph.D., MBA, St. Jude Division of Experimental Hematology director and Department of Hematology member, tested whether inhibiting menin could be a viable therapeutic strategy for myeloproliferative neoplasms.

Mind uploading: Can human brains be digitally copied? | Michael Levin and Lex Fridman

Lex Fridman Podcast full episode: • Michael Levin: Hidden Reality of Alien Int…
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GUEST BIO:
Michael Levin is a biologist at Tufts University working on novel ways to understand and control complex pattern formation in biological systems.

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Biological Robots: https://arxiv.org/abs/2207.00880
Classical Sorting Algorithms: https://arxiv.org/abs/2401.05375
Aging as a Morphostasis Defect: https://pubmed.ncbi.nlm.nih.gov/38636
TAME: https://arxiv.org/abs/2201.10346
Synthetic Living Machines: https://www.science.org/doi/10.1126/scirobotics.abf1571

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Rust-to-iron cycle may unlock long-term storage for renewable energy

In the future, iron might be used as a chemical energy storage material, making large quantities of renewable energy available in the long term. Iron powder is combusted in a cyclic process that is carbon neutral and then reconverted to its original state using energy input. Scientists at Karlsruhe Institute of Technology (KIT) were the first to conduct an extensive study to evaluate the potential of this technology for power generation. Their results show that iron, while not superseding hydrogen, may usefully complement it in a climate-neutral energy system. The findings have been published in Chem Circularity.

Be it for wind energy from coastal regions or for solar power from desert areas, iron could serve as a transportable energy carrier in the future to make these renewable energy sources usable worldwide. “This works in a cycle that emits no carbon dioxide or environmentally harmful substances,” said Julia Schuler from KIT’s Institute for Industrial Production (IIP). For power generation, iron powder is combusted, producing iron oxide, i.e. rust. Using hydrogen from renewable sources, it is reduced to iron again in a process that removes the oxygen it contains. The iron powder can then be reused.

“When burned, iron powder behaves very much like coal. We wanted to find out whether it was possible to repurpose existing coal power plants to iron-firing,” said Schuler. She believes that modifications are primarily necessary in the heat generator; other components, such as the steam cycle, turbines, generator and power grid connection, could continue to be used.

In a Flight of Starlings by Giorgio Parisi

From the 2021 Nobel Prize winner in Physics, an enlightening and personal journey into the practice of groundbreaking science.

“[Giorgio Parisi is] an extraordinary scientist.” —Carlo Rovelli

With In a Flight of Starlings, celebrated physicist Giorgio Parisi guides us through his unorthodox yet exhilarating work, starting with investigating the principles of physics by observing the flight of flocks of birds. Studying the movements of these communities, he has realized, proves an illuminating way into understanding complex systems of all kinds—collections of everything from atoms and planets to other animals, such as ourselves.

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