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Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet)

Joe Betts-LaCroix and Retro Biosciences recently raised funding at a $1.8 billion valuation. In his first podcast appearance since the announcement, Joe shares his vision for extending healthy human lifespan and the breakthroughs driving the longevity industry forward.

Joe Betts-LaCroix explains why aging is becoming a legitimate scientific target. He shares how new discoveries are turning longevity from speculation into measurable biology.

The conversation explores how AI is accelerating research, while highlighting why biology remains one of the hardest problems to solve. Even with smarter models, real-world testing and clinical trials still take time.

Joe also discusses Alzheimer’s, partial cellular reprogramming, and the future of longevity medicine. He shares why exercise remains the best longevity tool available today and what the next decade could look like for human health.

Joe is the CEO of Retro Biosciences and a longtime entrepreneur focused on science and technology. His mission is to extend healthy human lifespan and accelerate breakthroughs in aging research.

This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com.

A low-tech solution to the 6G problem—metacrystal panels offer cheap way to guide wireless signals around corners

A passive 3D-printed panel could redirect wireless signals around corners without electronics or power. The metacrystal design can handle multiple incoming waves and different frequency bands, offering a lower-cost option for hard-to-reach indoor spaces.


Basements, tunnels, large buildings—a weak Wi-Fi or mobile signal in these hard-to-reach places is frustrating. The usual solution is to add more electronics like routers, repeaters and base stations. Yet, as we move towards a 6G mobile network, this kind of complex infrastructure can be unsustainable and prohibitively expensive. Higher-frequency channels of 6G communications aim to provide vastly more data bandwidth than the current 5G, but those channels are more easily blocked by walls, people and other obstacles.

To tackle this, researchers at Aalto University have developed a new solution in the form of metacrystals: passive, 3D-printed smart panels that can shape wireless signals without electronics, a power supply or active tuning. The paper, “Metacrystals: Inversely-designed 3D-printed intelligent panels for 6G communications” is published in Nature Communications.

“When a room is too dark, you can bring in more lamps—or use simple mirrors to guide the already available light. This is what these metacrystals do, but with radio waves,” explains doctoral researcher Mahdi Asgari. “Unlike previously proposed single-layer intelligent surfaces, these volumetric metacrystals can be designed to control multiple incoming signals or frequency bands independently—a key requirement for realistic wireless communication.”

Quantum Space to go public in SPAC deal

WASHINGTON — Quantum Space, a company led by a former NASA administrator that is developing highly maneuverable spacecraft for national security missions, will go public by merging with a special purpose acquisition company, or SPAC.

Quantum Space announced June 8 that it will merge with Inflection Point Acquisition Corp. VI, a SPAC traded on the Nasdaq exchange. The companies expect the deal to close in the fourth quarter, with Quantum Space then trading on the Nasdaq under the ticker symbol QSPC.

The deal includes a $300 million investment, known as a private investment in public equity, or PIPE, by Inflection Point into Quantum Space. The SPAC also has $253 million in trust that would go to Quantum Space, assuming none of its shareholders redeem their shares. The deal would value Quantum Space at more than $1.1 billion if there are no SPAC redemptions.

Geoffrey Hinton Just Said AI Is Already Conscious

Full episode: • AI pioneer geoffrey hinton: AI is consciou…

Geoffrey Hinton — the Nobel Prize-winning physicist widely regarded as the Godfather of AI — sits down with Alex Kantrowitz on the Big Technology Podcast to discuss something he rarely says out loud: he believes AI is already conscious. Not eventually. Not theoretically. Already.
In this clip, Hinton dismantles the popular \.

Claude is Self-Evolving?

In this episode, I break down Anthropic’s research on recursive self-improvement—AI systems that can design and train the next generation with less human help—and why the key battleground is “taste” (choosing goals and next steps). I compare this to evolutionary algorithms and newer examples like DeepMind’s AlphaEvolve, Sakana’s Darwin Gödel Machine, and Karpathy’s AutoResearch, then cover METR Task Horizon and how task length has been doubling. I go through Anthropic’s internal results (Claude writing most merged code, speedup experiments, bug fixes, and a study where models sometimes pick better research next steps), plus the main skepticism: bad productivity metrics, internal-only models, and Goodhart’s Law/reward hacking. I end with an open safety problem where Claude agents closed the gap far faster than humans, and what this means for specifying and checking work.

LINKS:
https://www.anthropic.com/institute/r… voice to text App: whryte.com Website: https://engineerprompt.ai/ RAG Beyond Basics Course: https://prompt-s-site.thinkific.com/c… Signup for Newsletter, localgpt: https://tally.so/r/3y9bb0 Let’s Connect: 🦾 Discord: / discord ☕ Buy me a Coffee: https://ko-fi.com/promptengineering |🔴 Patreon: / promptengineering 💼Consulting: https://calendly.com/engineerprompt/c… 📧 Business Contact: [email protected] Become Member: http://tinyurl.com/y5h28s6h 💻 Pre-configured localGPT VM: https://bit.ly/localGPT (use Code: PromptEngineering for 50% off). Signup for Newsletter, localgpt: https://tally.so/r/3y9bb0 TIMESTAMP: 00:00 Self Improvement Basics 01:30 Evolutionary Loops Today 03:50 Task Horizon Doubling 05:18 Claude Productivity Claims 08:11 Goodhart’s Law 10:30 Agents as Researchers 12:22 What It Means for You.

My voice to text App: whryte.com.
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☕ Buy me a Coffee: https://ko-fi.com/promptengineering.
|🔴 Patreon: / promptengineering.
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📧 Business Contact: [email protected].
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Terahertz biophotonics: Understanding the path towards practical applications for biological imaging

Biophotonics is a multidisciplinary field that involves the development and application of light-based technologies to study, monitor and treat biological systems. The ability to directly image cells and molecules has led to many fundamental discoveries in the past century. More recently, the terahertz (THz) region of the electromagnetic spectrum has attracted growing interest as a promising frontier for advancing biological research.

The THz frequency range is associated with several fundamental biological processes. Although THz radiation is strongly absorbed by water—traditionally viewed as a limitation—this property can enable sensitive characterization of hydration states and water content. Compared with visible light, THz waves can also penetrate certain biological tissues more effectively.

However, despite steady advancements, the adoption of THz biophotonics still lags behind visible light-based techniques in directly observing cellular and molecular dynamics. This is largely due to several challenges, including relatively low spatial resolution (a consequence of the longer THz wavelengths), high sensitivity to water that complicates measurements, slower imaging speeds and bulky instrumentation. Fortunately, recent developments suggest strong future potential.

Lunar orbiter concept could reveal five key elements across moon in two years

Researchers from Tokyo Metropolitan University have used simulations to show that a newly developed, compact X-ray telescope could be used to map the chemical composition of the entire lunar surface, a vital breakthrough for understanding its geological evolution. Detailed modeling of the detector and a realistic satellite mission show that two years would be enough to map five key elements, while an array of 5-by-5 detectors could improve resolution and get results faster.

The geological evolution of the moon remains a mystery to scientists. This reflects how challenging it is to get accurate information, such as a complete map of the geochemistry of the lunar surface. Since we cannot readily go and collect samples from anywhere, scientists use a technology known as X-ray fluorescence imaging, in which detectors directed at the moon are used to pick up X-rays released by specific elements when they are hit by solar rays.

While observations during the Apollo and Chandrayaan missions have successfully yielded partial maps, we are nowhere near a comprehensive map that might illuminate lunar geology. This is due to significant technical challenges, including a lack of sufficient illumination by solar rays during the lifetime of a mission and degradation of the detector. The illumination issue is particularly pronounced in polar regions, where solar X-rays are much weaker.

Superheated magma may explain why similar volcanoes erupt in very different ways

Scientists have shed light on a thermal process in magma that may help explain why similar volcanic systems can produce very different eruptive behaviors.

An international team, led by The University of Manchester, studied magma from the 2021 Tajogaite eruption on La Palma, Spain, and found that “superheating”—a state in which magma is heated above the temperature at which crystals are stable—can strongly delay the formation of crystals as magma rises towards Earth’s surface.

Published in Nature Communications, the study shows that high temperatures can dissolve tiny pre-existing crystal “seeds” that normally help new crystals begin to form. Superheating also changes the internal structure of the magma, making it more uniform, and less able to support the formation of new crystals. This influences how quickly magma rises and how easily volcanic gases can escape, both of which play an important role in determining how explosive the eruption will be.

Newly discovered view of brain blood flow during surgery could prevent debilitation, save lives

Tracking the brain’s blood flow during neurosurgery represents one of the most critical and challenging parts of the operation. A brief interruption can mean the difference between permanent damage and full recovery, but it’s difficult to track blood flow across the surgical field.

Now, researchers at The University of Texas at Austin have developed a new way to monitor blood flow with standard camera hardware. The method, called sinusoidal intensity modulation speckle imaging (SIMSI), uses the physics of dynamic light scattering to image blood flow noninvasively, across a wide field of view and without high-speed cameras. The paper is published in the journal Proceedings of the National Academy of Sciences.

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