Goupille et al. describe an alternative approach targeting the host and tumoral primary metabolism in FLT3-mutant leukemia. Ketogenic diet strategies aiming to imbalance lipid homeostasis augment fatty acid and amino acid degradative activity, attenuating FLT3 signaling activation, cell proliferation, and leukemia progression upon targeted therapies.
In February 2026, Rosatom announced a prototype plasma rocket engine that its scientists claim could reduce the travel time to Mars from eight months to thirty days. The engine, built at a dedicated facility in Troitsk and tested inside a fourteen-metre vacuum chamber designed to simulate deep space, uses electromagnetic fields to ionise hydrogen into […].
Artificial intelligence is now finding planets human astronomers missed and scanning for alien signals 600 times faster than ever before.
Yet the more powerful our search tools become, the louder the silence from the cosmos grows.
This video explores why the same technology helping us look for extraterrestrial life may also explain why we cannot find any.
We examine the Great Filter hypothesis, the mathematics of self-replicating probes, and the growing consensus that any aliens out there would be machines, not biological beings.
From Matrioshka brains to the aestivation hypothesis to the Dark Forest, the universe may be hiding minds we cannot recognise, or warning us about a test every civilisation faces.
Chapters.
00:00 — Intro.
Researchers have proposed new standards into the decades-old prosthetic donations market, improving the quality of lower limb prosthetic feet by two-thirds—a major quality of life boost for recipients.
An interdisciplinary team of charities, prosthetists and academics led by King’s College London designed and implemented the very first set of standardized regulations for exporting prosthetic feet to the Global South, reducing unusable donations from 16% to 5%.
In so doing, the team have laid the foundation for improved prosthetics provision in the UK and an ethical framework for a global circular economy of prosthetics—the first of its kind.
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In 1995, when Michel Mayor and Didier Queloz confirmed the first exoplanet orbiting a Sun-like star, the discovery answered one question but ignited a far deeper one: if planets are everywhere, could life be as well. For decades, this remained speculation, until a new generation of instruments transformed astronomy into something far more intimate. Using the Hubble Space Telescope and later the far more powerful James Webb Space Telescope, scientists began analyzing the atmospheres of distant worlds by capturing the faint starlight filtering through them, decoding chemical fingerprints from across hundreds of light-years.
Why haven’t we found aliens yet? From the Fermi Paradox to the Great Filter, the Dark Forest theory, rare Earth, simulation theory, and more — here’s every major explanation for why the universe seems so silent.
00:00 The Fermi Paradox.
00:54 The Great Filter.
01:45 The Rare Earth Hypothesis.
02:40 The Dark Forest Theory.
03:36 The Zoo Hypothesis.
04:34 The Self-Destruction Filter.
05:35 The Simulation Hypothesis.
06:33 The Communication Gap.
07:35 The Interstellar Distance Problem.
08:35 The Short Window Problem.
09:32 The Planetarium Hypothesis.
10:30 The Transcension Hypothesis
Why haven’t aliens contacted Earth?
The universe contains hundreds of billions of galaxies, each filled with billions of stars and potentially habitable planets. Yet despite the vastness of the cosmos, we have never detected a single confirmed extraterrestrial civilization.
This mystery is known as the Fermi Paradox.
In this video, we explore 10 chilling theories that attempt to explain the silence of the universe — from the terrifying Dark Forest Hypothesis to the existential threat of the Great Filter.
Some theories suggest aliens are hiding.
Others suggest they are waiting.
And some suggest something far more disturbing.
If any of these theories are true, humanity may not be alone… but we may wish we were.
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