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Light-based nanotechnology offers potential alternative to chemotherapy and radiation

Researchers at NYU Abu Dhabi have developed a new light-based nanotechnology that could improve how certain cancers are detected and treated, offering a more precise and potentially less harmful alternative to chemotherapy, radiation, and surgery. The study advances photothermal therapy, a treatment approach that uses light to generate heat inside tumors and destroy cancer cells.

The research is published in the journal Cell Reports Physical Science.

The NYU Abu Dhabi team designed tiny, biocompatible and biodegradable nanoparticles that carry a dye activated by near-infrared light. When exposed to this light, the particles heat up, damaging tumor tissue while minimizing harm to healthy cells. Near-infrared light was chosen specifically as it penetrates the body to greater depth than visible light, thereby enabling treatment of tumors that are not close to the surface.

A new flexible AI chip for smart wearables is thinner than a human hair

The promise of smart wearables is often talked up, and while there have been some impressive innovations, we are still not seeing their full potential. Among the things holding them back is that the chips that operate them are stiff, brittle, and power-hungry. To overcome these problems, researchers from Tsinghua University and Peking University in China have developed FLEXI, a new family of flexible chips. They are thinner than a human hair, flexible enough to be folded thousands of times, and incorporate AI.

A flexible solution

In a paper published in the journal Nature, the team details the design of their chip and how it can handle complex AI tasks, such as processing data from body sensors to identify health indicators, such as irregular heartbeats, in real time.

Tiny silicon structures compute with heat, achieving 99% accurate matrix multiplication

MIT researchers have designed silicon structures that can perform calculations in an electronic device using excess heat instead of electricity. These tiny structures could someday enable more energy-efficient computation. In this computing method, input data are encoded as a set of temperatures using the waste heat already present in a device.

The flow and distribution of heat through a specially designed material forms the basis of the calculation. Then the output is represented by the power collected at the other end, which is a thermostat at a fixed temperature.

The researchers used these structures to perform matrix vector multiplication with more than 99% accuracy. Matrix multiplication is the fundamental mathematical technique machine-learning models like LLMs utilize to process information and make predictions.

New light-emitting artificial neurons could run AI systems more reliably

Over the past decades, computer scientists have developed increasingly advanced artificial intelligence (AI) systems that perform well on various tasks, including the analysis or generation of images, videos, audio recordings and texts. These systems power various highly performing software, including automated transcription apps, large language model (LLM)-powered conversational agents like ChatGPT, and various other platforms.

Mapping ‘figure 8’ Fermi surfaces to pinpoint future chiral conductors

One of the biggest problems facing modern microelectronics is that computer chips can no longer be made arbitrarily smaller and more efficient. Materials used to date, such as copper, are reaching their limits because their resistivity increases dramatically when they become too small. Chiral materials could provide a solution here. These materials behave like left and right hands: they look almost identical and are mirror images of each other, but cannot be made to match.

“It is assumed that the resistivity in some chiral materials remains constant or even decreases as the chiral material becomes smaller. That is why we are working on using electronic chirality to develop materials for a new generation of microchips that are faster, more energy-efficient and more robust than today’s technologies,” says Professor Niels Schröter from the Institute of Physics at MLU. Until now, however, it has been difficult to produce thin layers of these materials without the left-and right-handed areas canceling each other out in their effects.

This is precisely where the new study, in which the Max Planck Institute for Microstructure Physics in Halle was also involved, comes in. “For the first time, we have found materials that are not yet chiral themselves. However, they have the potential to be converted into electronically chiral materials with only a single-handedness through targeted distortion. These achiral materials can serve as so-called parent materials for engineering chiral conductors with reduced resistivity,” explains Schröter.

Refractive-index microscope measures a sample’s optical properties with pinpoint accuracy

In this way, and almost by chance, researchers at TU Wien developed a novel microscopy technique that allows the refractive index of biological samples to be measured at a resolution far below what conventional light microscopy theory would seem to allow. Their paper is published in the journal ACS Nano.

The trick behind resolution beyond the wavelength of light

What happens if you try to image two molecules whose separation is smaller than the wavelength of light? You will not see two distinct points, but a single blurred spot of light—the images of the two molecules overlap, no matter how precise the microscope is.

Scientists develop high-performance Hg-based crystal for mid-far infrared birefringence

Mid- and far-infrared birefringent crystals are key functional materials for polarization control, laser technologies, and infrared photonics. However, existing materials generally suffer from limited infrared transparency, an intrinsic trade-off between large birefringence and wide transmission windows, and challenges in optical characterization due to restricted crystal dimensions.

New Study Reveals How Nanoplastics Make Bacteria More Dangerous

Nanoplastics already raise fears because people can ingest them directly. Now scientists say these tiny particles can create a different kind of danger when they end up in water: they can help bacteria become tougher and harder to remove.

A study in Water Research led by Virginia Tech’s Jingqiu Liao, working with international collaborators, found that nanoplastics can influence how environmental microbes behave in ways that may indirectly affect human health. The concern is not just what the particles might do in the body, but what they might encourage in the water systems people rely on every day.

“It is very important to better understand the adverse effects of the nanoplastics on human health, and not just in humans but also in the environment, which indirectly influences human health,” said Liao, assistant professor of civil and environmental engineering. “The nanoplastics can make the antimicrobial-resistant pathogens better survive, which could be harmful to the environment and would have public health implications.”

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