Lifeboat Foundation

A study led by Umeå University, Sweden, presents new insights into how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

“The discovery opens a new track for future research into developing new and more effective treatments for certain cancers,” says Francesca Aguilo, associate professor at the Department of Molecular Biology at Umeå University and leader of the study in collaboration with various institutions including the University of Pavia, University of Texas Health Science Center at Houston, Universidad de Extremadura, and others.

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation. Although all cells share the same origin and share the same genetic information, specialized cells use the information in different ways to perform different functions. This process is regulated by genetic and epigenetic mechanisms.

OpenAI is set to release the full o1 reasoning model sometime this year, but an unexpected leak last week means we may have already seen it in action — and it is even better than we expected.

On this episode, neuroscientist and author Robert Sapolsky joins Nate to discuss the structure of the human brain and its implication on behavior and our ability to change. Dr. Sapolsky also unpacks how the innate quality of a biological organism shaped by evolution and the surrounding environment — meaning all animals, including humans — leads him to believe that there is no such thing as free will, at least how we think about it today. How do our past and present hormone levels, hunger, stress, and more affect the way we make decisions? What implications does this have in a future headed towards lower energy and resource availability? How can our species manage the mismatch of our evolutionary biology with our modern day challenges — and navigate through a ‘determined’ future?

About Robert Sapolsky:

Continue reading “Robert Sapolsky: ‘The Brain, Determinism, and Cultural Implications’ | The Great Simplification #88” »

In a world where choices seem endless, could it be that our ‘free will’ is nothing more than an illusion?

When it comes to things like choosing a morning run over an extra hour of sleep, opting for an apple instead of that enticing pint of ice cream, or quitting your job on a whim…

Continue reading “Is There Free Will? The Unsettling Science Behind Our Everyday Decisions | Dr. Robert Sapolsky” »

Patreon: https://www.patreon.com/seanmcarrollBlog post with audio player, show notes, and transcript: https://www.preposterousuniverse.com/podcast/2024/11/04…

Physicists at Rice University and their collaborators have made a discovery that sheds new light on magnetism and electronic interactions in advanced materials, with the potential to transform technologies like quantum computing and high-temperature superconductors.

Led by Zheng Ren and Ming Yi, the research team’s study on iron-tin (FeSn) thin films reshapes scientific understanding of kagome magnets — materials named after an ancient basket-weaving pattern and structured in a unique, latticelike design that can create unusual magnetic and electronic behaviors due to the quantum destructive interference of the electronic wave function.

The findings, published in Nature Communications, reveal that FeSn’s magnetic properties arise from localized electrons, not the mobile electrons scientists previously thought. This discovery challenges existing theories about magnetism in kagome metals in which itinerant electrons were assumed to drive magnetic behavior. By providing a new perspective on magnetism, the research team’s work could guide the development of materials with tailored properties for advanced tech applications such as quantum computing and superconductors.

Scientists in China have managed to revive brain activity in pigs nearly an hour after circulation ceased, thanks to the surprising involvement of the liver.

If translatable to humans, this finding could have significant implications for extending the critical window in which doctors can resuscitate patients following sudden cardiac arrest.

The research team, led by Dr. Xiaoshun He at Sun Yat-Sen University, experimented with the brains of 17 Tibetan minipigs to investigate how the liver might influence brain recovery.

Hello!

IEEE Annals of the History of Computing’s new Editor-in-Chief Troy Astarte introduces themself and their background.

Two researchers at The University of Alabama in Huntsville (UAH) have published a paper that demonstrates for the first time that a subluminal warp drive is possible within the bounds of known physics without the need to employ exotic unknown forms of matter or energy, while also advancing our understanding of gravity. UAH alumnus Dr. Jared Fuchs led a team of physicists that produced the paper, supported by Dr. Christopher Helmerich, also an alumnus of UAH, a part of the University of Alabama System, both working in conjunction with the New York-based Applied Propulsion Laboratory of Applied Physics (APL).

When Mexican physicist Miguel Alcubierre first proposed his theoretical warp drive in 1994, the concept required a bubble of ‘negative energy density’ around an object to create an imbalance in space-time, generating motion without movement of the craft, thus avoiding violations of the speed-of-light limit. But the Star Trek dream comes with a catch: it would have to be powered by either exotic particles that haven’t yet been discovered, or the mysterious dark energy thought to drive the expansion of the universe, currently viewed by most physicists as not remotely achievable.

Fuch’s team’s Constant-Velocity Subluminal Warp Drive, however, offers a new means of propulsion that allows it to operate at constant subluminal speeds, while still conforming to Einstein’s theory of general relativity, with no need for ‘unphysical’ forms of matter required by previous designs.