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In what researchers have called an “unprecedented” response, a new drug that treats locally advanced rectal cancer has shown to have completely eradicated tumors in all 42 patients who took part in the Phase II trial.

The drug, Jemperli (dostarlimab-gxly), had earlier shown great potential for eliminating mismatch repair deficient (dMMR) cancers, which make up 5–10% of colorectal cancers. Following the Phase II trial, the first 24 patients assessed showed a “sustained complete clinical response” – no cancer evident – after an average of 26.3 months.

“These findings demonstrate the potential of dostarlimab-gxly as a novel approach to treating locally advanced dMMR rectal cancer that leads to durable complete tumor regression without the need for life-altering treatment,” said Dr Andrea Cercek, researcher and oncologist at the Memorial Sloan Kettering Cancer Center (MSK). “As a clinician, I’ve seen firsthand the debilitating impact of standard treatment of dMMR rectal cancer and am thrilled about the potential of dostarlimab-gxly in these patients.”

Basically confirmed whats been said here. AI will take over film making by 2029/2030.


Actor and entrepreneur Ashton Kutcher lauded OpenAI’s generative AI video tool Sora at a recent event. “I’ve been playing around with Sora, this latest thing that OpenAI launched that generates video,” Kutcher said. “I have a beta version of it, and it’s pretty amazing. Like, it’s pretty good.”

He explained that users specify the shot, scene, or trailer they desire. “It invents that thing. You haven’t shot any footage, the people in it don’t exist,” he said.

New long-term agreement will help provide responsive access to space for future tech demonstration spacecraft

Cedar Park, Texas, June 5, 2024Firefly Aerospace, Inc., an end-to-end space transportation company, today announced it signed a multi-launch agreement with Lockheed Martin for 25 launches on Firefly’s Alpha rocket through 2029. This agreement commits Lockheed Martin to 15 launch reservations and 10 optional launches.

“Firefly is honored to continue this partnership with Lockheed Martin and appreciates their confidence in our rapid launch services to support their critical missions for years to come,” said Bill Weber, CEO of Firefly Aerospace. “The Firefly team has scaled up Alpha production and testing and significantly streamlined our launch operations to fly Alpha more frequently and responsively. This allows us to continue delivering the one metric ton rocket the industry is demanding.”

Making Humanity A Multi-Planetary Species — Dr. Eliah Overbey, Ph.D. — Assistant Professor, Bioastronautics, University of Austin; CSO, BioAstra.


Dr. Eliah Overbey, Ph.D. is Assistant Professor of Bioastronautics at The University of Austin (UATX — https://www.uaustin.org/people/eliah–…) where she is involved in pioneering research in the field of astronaut health, specializing in spaceflight-induced genomic changes. Her work focuses on mapping changes in the human body during spaceflight and developing Earth-independent laboratories to make humans a multi-planetary species (https://www.eliahoverbey.com/).

Dr. Overbey comes to UATX from her previous position as a Research Associate at Weill Cornell Medicine.

The core theory, weak vs. strong emergence, micro-reductionism, and Sean Carroll’s skeptical argument against everything. Is Dr. Carroll correct in holding that physics has ruled out the afterlife, an immaterial soul, fundamental consciousness, and parapsychology?

Linktree https://linktr.ee/emersongreen.

LINKS

Sean Carroll speaking to the Freedom From Religion Foundation • Sean Carroll: Has Science Refuted Rel…