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The mTOR Inhibitors Lifespan Project Enters Next Phase

Ora Biomedical, in partnership with Rapamycin Longevity Lab, announces the successful funding of the first subproject under its ambitious initiative to conduct a rapid lifespan analysis of 601 mTOR inhibitors in roundworms.

With $50,000 secured, Ora Biomedical will now commence the next phase of the first subproject. This will be a high-throughput screening of 301 mTOR inhibitors using its cutting-edge WormBot-AI technology. This milestone marks an important step toward identifying next-generation compounds that could be more effective than rapamycin, which is currently seen as the golden standard because of its good longevity effects in multiple species.

Mitchell Lee, CEO of Ora Biomedical, emphasized the importance of this research by stating: “The potential of targeting aging to broadly improve healthy lifespan is clear from decades of studies with compounds like rapamycin. However, even for well-validated molecular targets like mTOR, we still don’t know the best interventions. We at Ora Biomedical are proud to partner with Rapamycin Longevity Lab to advance our understanding around targeting mTOR and related kinases for maximizing healthy lifespan. None of this work is possible without support from visionary donors and organizations like the Lifespan Research Institute, the nonprofit behind Lifespan.io, with whom we have partnered to create pathways for donations to advance longevity science. To all those involved, thank you again, and we are excited to get to work!”

US firm’s light-powered computer tackles energy-hungry AI problems

Silicon Valley startup Lightmatter has developed a novel computer chip that can speed up artificial intelligence processes and save electricity in the process. The company focuses on using beams of light to move data between computers rather than using electric signals.

Connection speeds are a great matter of concern when it comes to artificial intelligence due to its complex software. This complexity requires the software to be spread over many computers.

The UK Develops AI “Murder Prediction” Tool | Vantage with Palki Sharma | N18G

The UK is developing a controversial AI tool to predict potential murderers using personal data from convicts, victims, and witnesses. Aimed at preventing crime, the initiative mirrors global trends in AI policing. However, critics warn of bias, privacy issues, and call the project “chilling and dystopian,” raising ethical concerns about pre-crime technology.

UK | artificial intelligence | AI | murder | firstpost | world news | news live | vantage | palki sharma | news.

#uk #ai #murder #firstpost #vantageonfirstpost #palkisharma #worldnews.

Vantage is a ground-breaking news, opinions, and current affairs show from Firstpost. Catering to a global audience, Vantage covers the biggest news stories from a 360-degree perspective, giving viewers a chance to assess the impact of world events through a uniquely Indian lens.

The show is anchored by Palki Sharma, Managing Editor, Firstpost.

Beyond the hype, how industries are deploying AI at the heart of their operations

There was the hype, then the testing, now companies are deploying artificial intelligence at the heart of their operations. We ask one of the world’s most prominent AI scientists for his advice for companies, and hear how Siemens is creating the ‘brains’ to run the factories of the future.

Revealing the largest wiring diagram and functional map of the brain

How does the brain work? Where, and when, and why do neurons connect and send their signals? Scientists have created the largest wiring diagram and functional map of an animal brain to date to learn more. Research teams at Allen Institute, @BCMweb and @princeton worked together to map half a billion synapses, over 200,000 cells, and 4km of axons from a cubic millimeter of mouse brain, providing unparalleled detail into its structure and functional properties. The project is part of the Machine Intelligence from Cortical Networks (MICrONS) program, which seeks to revolutionize machine learning by reverse-engineering the algorithms of the brain. Research findings reveal key insights into brain activity, connectivity, and structure—shedding light on both form and function—within a region of the mouse visual cortex that plays a critical role in brain health and is often disrupted in neurological conditions such as Alzheimer’s disease, autism, and addiction. These insights could revolutionize our ability to treat neuropsychiatric diseases or study the influence of drugs and other changes on the brain.

This extraordinary achievement begins to reveal the elusive language the brain uses to communicate amongst its millions of cells and the cortical mechanisms of intelligence—one of the holy grails of science.

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Access open science data: https://www.microns-explorer.org/
Explore the publications in Nature: https://www.nature.com/immersive/d428

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