Lifeboat Foundation

Studies of massive genetic databases may lead to new therapies for mental disorders.

Why do our brains — and the brains of other animals — have so many folds?

Compare an analog and a digital audio recording medium. VHS video tape — an analog medium — stores a continuous curve of modulated audio/visual information. In a digital CD continuous audio is sliced into 44,100 frames a second, and represented by discrete numbers.

On playback the sounds are presented as continuous, much as the individual still frames of a motion picture appear continuous when played back fast enough. Most people can’t hear the difference between digital and analog recordings, me included, but those who say they do may spend thousands on turntables and tube amps to get the full analog experience.

From measurements, we know that neuron currents are continuous, not step functions. The important question is how is the information represented by these signals? Most psychological research assumes continuous or analog representation, but in the lengthy paper Is Information in the Brain Represented in Continuous or Discrete Form? James Tee and Desmond Taylor of the University of Canterbury make a strong theoretical and experimental case for digital data.

Continue reading “Is your brain an analog or digital device? New research surprises” »

Ever watch ‘Your Brain on Blank’? Ever have a question about the brain? Then you’re in the right place. Join us as neuroscience Ph.D. candidate Shannon Odell takes a few minutes to answer some of the write-in questions from our viewers about how different stimuli affect your brain.

Experiments in mice have shown for the first time that bacteria found in the gut of babies and children seem to play a role in brain development.

Scientists used stem cells to grow a miniature model of a Neanderthal’s brain for the first time. The tiny blob of neurons reveals what makes us different.

An expanding arcade of video games takes aim at easing autism traits, from poor visual attention to problems with motor skills, but the evidence of the games’ effectiveness remains limited.

Only 35 per cent of five- to 17-year-olds and 62 per cent of children ages 3 and 4 are getting the recommended physical-activity levels for their age group (Editor’s note: around 60 minutes of moderate-to-vigorous physical activity daily, including vigorous-intensity activity on at least 3 days per week) and that this may be having an impact on the health of their brains.

___ Getting kids outside and active could help with brain health: Participaction report (The Globe and Mail): The physical benefits of kids leading an active lifestyle, including better heart heal…

A group of researchers from Yale University and Agilent Technologies have developed a #syntheticbiology technique that turns bacterium E. Coli into a phosphorylated protein factory capable of churning out every known instance of this modification in human proteins.

Proteins, the end product of genes, carry out life functions. Most human proteins are modified by a process called serine phosphorylation — a chemical switch that can alter their structure and function. Malfunctions in this process have been implicated in diseases such as cancer and Alzheimer’s yet are difficult to detect and study. A group of researchers from Yale University and Agilent Technologies have developed a synthetic biology technique that turns bacterium E. Coli into a phosphorylated protein factory capable of churning out every known instance of this modification in human proteins.

“We synthesized over 110,000 phosphoproteins from scratch and we can now study how they all function together,” said Jesse Rinehart, associate professor of cellular and molecular physiology at the Systems Biology Institute and senior author of the research. “This is the future of scientific research — we can build everything we study.”

Continue reading “New platform will help create designer human proteins in the lab” »