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Dr. Stephani Otte, Ph.D. — Chan Zuckerberg Initiative — Measuring Human Biology in Action

Measuring Human Biology in Action, To Cure, Prevent Or Manage All Diseases — Dr. Stephani Otte, Ph.D., Science Program Officer, Imaging, Chan Zuckerberg Initiative.


Dr. Stephani Otte, Ph.D is Science Program Officer, Imaging, at the Chan Zuckerberg Initiative (https://chanzuckerberg.com/), who leads the organization’s Imaging program and is focused on the creation, dissemination, optimization, and standardization of transformative imaging technologies.

Prior to CZI, Dr. Otte was Director of Science at a neuro-technology / microscopy company, Inscopix, involved in accelerating brain science and innovating mini-scope microscope solutions for real-time mapping of the human brain and it’s circuits.

Dr. Otte received her Ph.D. in Neuroscience at the University of California, San Diego, and did postdoctoral fellowships in systems neuroscience at the Salk Institute and University of California, Berkeley.

The Chan Zuckerberg Initiative is an organization established and owned by Dr. Priscilla Chan and her husband, Facebook founder Mark Zuckerberg, with a focus on science, education, immigration reform, housing, criminal justice, and other local issues, with a mission to “build a more inclusive, just, and healthy future for everyone” and to “advance human potential and promote equality in areas such as health, education, scientific research and energy”.

The Neuroscience of Consciousness

𝐒𝐭𝐚𝐧𝐟𝐨𝐫𝐝 𝐄𝐧𝐜𝐲𝐜𝐥𝐨𝐩𝐞𝐝𝐢𝐚 𝐨𝐟 𝐏𝐡𝐢𝐥𝐨𝐬𝐨𝐩𝐡𝐲:

The Neuro-Network.

𝐓𝐡𝐞 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐨𝐟 𝐂𝐨𝐧𝐬𝐜𝐢𝐨𝐮𝐬𝐧𝐞𝐬𝐬.

First published Tue Oct 9, 2018.


Conscious experience in humans depends on brain activity, so neuroscience will contribute to explaining consciousness. What would it be for neuroscience to explain consciousness? How much progress has neuroscience made in doing so? What challenges does it face? How can it meet those challenges? What is the philosophical significance of its findings? This entry addresses these and related questions.

To bridge the gulf between brain and consciousness, we need neural data, computational and psychological models, and philosophical analysis to identify principles to connect brain activity to conscious experience in an illuminating way. This entry will focus on identifying such principles without shying away from the neural details. The notion of neuroscientific explanation here conceives of it as providing informative answers to concrete questions that can be addressed by neuroscientific approaches. Accordingly, the theories and data to be considered will be organized around constructing answers to two questions (see section 1.4 for more precise formulations):

Elon Musk’s brain-implant startup Neuralink may have misled regulators about Musk’s leadership role

Neuralink, the startup cofounded and run by Elon Musk that hopes to implant computer chips in people’s brains, may have misled federal securities regulators about the billionaire entrepreneur’s role at the company.

That’s according to government documents and Fortune interviews with securities lawyers and a half-dozen former employees of the company. The employees mostly spoke anonymously out of concern for violating nondisclosure agreements and possible retaliation from Musk.

The episode involves a 2018 letter in which an attorney representing Neuralink downplayed Musk’s leadership role at the company in a letter to the Securities and Exchange Commission. The attorney’s characterization contradicts former employees’ accounts, which depict Musk as very much in charge. Neuralink and the attorney involved in the filing did not respond to requests for comment. lawyer for Neuralink told the SEC that Musk had “no executive or management role” at the company. Former employees say that’s far from the truth.

The Omega Singularity: The Cosmological Projector of All Possible Timelines

E verything is Code. Immersive [self-]simulacra. We all are waves on the surface of eternal ocean of pure, vibrant consciousness in motion, self-referential creative divine force expressing oneself in an exhaustible variety of forms and patterns throughout the multiverse of universes. “I am” the Alpha, Theta & Omega – the ultimate self-causation, self-reflection and self-manifestation instantiated by mathematical codes and projective fractal geometry.

In my new volume of The Cybernetic Theory of Mind series – The Omega Singularity: Universal Mind & The Fractal Multiverse – we discuss a number of perspectives on quantum cosmology, computational physics, theosophy and eschatology. How could dimensionality be transcended yet again? What is the fractal multiverse? Is our universe a “metaverse” in a universe up? What is the ultimate destiny of our universe? Why does it matter to us? What is the Omega Singularity?

Insight Into How the Brain Multitasks While Walking

Summary: Walking patterns improve when people embarked on cognitive tasks at the same time, suggesting people are more stable while walking and performing tasks than when they solely focus on walking.

Source: University of Rochester.

New research turns the old idiom about not being able to walk and chew gum on its head. Scientists with the Del Monte Institute for Neuroscience at the University of Rochester have shown that the healthy brain is able to multitask while walking without sacrificing how either activity is accomplished.

Iron Accumulation Linked With Age-Related Cognitive Decline

Summary: A breakdown in regulatory mechanisms causes iron to build up in the brain during aging, increasing oxidative stress and increasing the risk of age-related cognitive decline, a new study reports.

Source: Northwestern University.

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

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