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Archive for the ‘neuroscience’ category: Page 522

Jan 11, 2020

Scientists find missing protein in brain that causes autism

Posted by in category: neuroscience

Scientists have discovered that when an essential key protein needed to generate novel brain cells during pregnancy and early childhood days of the offspring is missing, which makes the brain goes haywire. This particular deprivation causes an imbalance in brain’s circuitry can lead to long-term cognitive and movement behaviours characteristic of autism spectrum disorder.” During brain development, there is a coordinated series of events that have to occur at the right time and the right place in order to establish the appropriate number of cells with the right connections,” said Juan Pablo Zanin, Rutgers-Newark research associate, and lead author.” Each of these steps is carefully regulated and if any of these steps are not regulated correctly, this can impact behaviour.

Jan 11, 2020

Rejuvenating the brain: More stem cells improve learning and memory of old mice

Posted by in categories: biotech/medical, neuroscience

Summary: Critical aspects of hippocampal function can be reversed in old age, or compensated for throughout life, with the help of neural stem cells. Source: TU DresdenWe all will experience it.

Jan 10, 2020

A unique brain signal may be the key to human intelligence

Posted by in category: neuroscience

Scientists exploring human neurons directly learn some remarkable things.

Jan 10, 2020

We all will experience it at some point, unfortunately: The older we get the more our brains will find it difficult to learn and remember new things

Posted by in categories: biotech/medical, life extension, neuroscience, robotics/AI

What the reasons underlying these impairments are is yet unclear but scientists at the Center for Regenerative Therapies of TU Dresden (CRTD) wanted to investigate if increasing the number of stem cells in the brain would help in recovering cognitive functions, such as learning and memory, that are lost during ageing.”

https://tu-dresden.de/tu-dresden/newsportal/news/verjuengung…en-maeusen

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Jan 9, 2020

Unique Brain Signal Just Discovered. And It Might Make Us ‘Human’

Posted by in categories: computing, neuroscience

A new study suggests that human neurons may have more computing power than once thought.

Jan 9, 2020

Missing protein in brain causes behaviors mirroring autism

Posted by in categories: biotech/medical, genetics, neuroscience

Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire—causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder.

“During , there is a coordinated series of events that have to occur at the right time and the right place in order to establish the appropriate number of cells with the right connections,” said Juan Pablo Zanin, Rutgers-Newark research associate and lead author on a paper published in the Journal of Neuroscience.” Each of these steps is carefully regulated and if any of these steps are not regulated correctly, this can impact behavior.”

Zanin has been working with Wilma Friedman, professor of cellular neurobiology in the Department of Biological Sciences, studying the p75NTR —needed to regulate —to determine its exact function in brain development, gain a better understanding of how this genetic mutation could cause to die off and discover whether there is a genetic link to autism or like Alzheimer’s.

Jan 9, 2020

Nanoparticles deliver ‘suicide gene’ therapy to pediatric brain tumors growing in mice

Posted by in categories: biotech/medical, nanotechnology, neuroscience

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a “suicide gene” to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals’ survival.

In their study, described in a report published January 2020 in the journal Nanomedicine: Nanotechnology, Biology and Medicine, the researchers caution that for safety and biological reasons, it is unlikely that the herpes simplex virus type I thymidine kinase (HSVtk)—which makes tumor cells more sensitive to the lethal effects of the anti-viral drug ganciclovir—could be the exact therapy used to treat human medulloblastoma and atypical teratoid/rhabdoid tumors (AT/RT) in children.

So-called “suicide ” have been studied and used in cancer treatments for more than 25 years. The HSVtk gene makes an enzyme that helps restore the function of natural tumor suppression.

Jan 9, 2020

Dendritic action potentials and computation in human layer 2/3 cortical neurons

Posted by in categories: biotech/medical, neuroscience, robotics/AI

A new unique signal discovered within the brain might be what makes us human:

https://science.sciencemag.org/content/367/6473/83

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Jan 8, 2020

Virus Spread by Shrews Linked to Human Deaths from Mysterious Brain Infections

Posted by in categories: biotech/medical, neuroscience

The pathogen has been newly identified in eight cases of encephalitis in Germany over the past 20 years.

Jan 7, 2020

How a chunk of human brain survived intact for 2600 years

Posted by in category: neuroscience

Unusual protein aggregates could have preserved the Iron Age brain.