Sound waves can cross the blood-brain barrier and could deliver chemotherapy to complex and treatment-resistant glioblastomas.
Category: neuroscience – Page 354
High-grade gliomas functionally remodel neural circuits in the human brain, promoting tumour progression and impairing cognition.
CHICAGO, May 3 (Reuters) — An experimental Alzheimer’s drug developed by Eli Lilly and Co (LLY.N) slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease.
Lilly’s drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer’s by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer’s proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death.
The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB).
Neurotech will bring many amazing positive changes to the world, such as treating ailments like blindness, depression, and epilepsy, giving us superhuman sensory capabilities that allow us to understand the world in new ways, accelerating our ability to cognitively process information, and more. But in an increasingly connected society, neuroprivacy will represent a crucial concern of the future. We must carefully devise legal protections against misuse of “mind reading” technology as well as heavily invest in “neurocybersecurity” R&D to prevent violation of people’s inner thoughts and feelings by authorities and malignant hackers. We can capitalize on the advantages, but we must do establish safety mechanisms as these technologies mature. #neurotechnology #neuroscience #neurotech #computationalbiology #future #brain
Determining how the brain creates meaning from language is enormously difficult, says Francisco Pereira, a neuroscientist at the US National Institute of Mental Health in Bethesda, Maryland. “It’s impressive to see someone pull it off.”‘
‘Wake-up call’
Neuroethicists are split on whether the latest advance represents a threat to mental privacy. “I’m not calling for panic, but the development of sophisticated, non-invasive technologies like this one seems to be closer on the horizon than we expected,” says bioethicist Gabriel Lázaro-Muñoz at Harvard Medical School in Boston. “I think it’s a big wake-up call for policymakers and the public.”
Our research found that concussion was associated with increased functional connectivity between the thalamus and the rest of the brain very shortly after injury, when compared to 76 healthy control subjects.
In other words, the thalamus was trying to communicate more as a result of the injury. This was despite routine MRI and CT imaging showing no structural changes in the brain.
While many of us would assume that more connectivity in the brain is a good thing, research looking at more severe head injuries indicates that greater connectivity between brain regions might actually be a sign of the brain trying to compensate and offset damage across the brain.
Given the rise of chat gpt and its volumes of knowledge bases there is a new chat bot that is aiding mental health care and therapy 😀
When it comes to mental health, the main focus is on the patient and how to provide the best care possible. But with the rising demand for mental health services, it’s increasingly difficult for clinicians to address the individual needs of their patients and meet the growing demand for mental health services. This is where ChAT-GPT, or Conversational Artificial intelligence-based Therapy for Generalized Psychological Treatment, comes in.
Chat-GPT is an AI-based therapy that uses natural language processing (NLP) and conversational AI to help therapists provide more personalized and effective mental health care and therapy. This new technology allows mental health professionals to provide real-time and personalized care to their patients in a way that is tailored to their needs and preferences. In this article, we will discuss the key features of Chat-GPT and how it is helping improve mental health care and therapy.
Chat-GPT is a type of AI-based therapy developed by researchers at Albert Einstein College of Medicine. It is a conversational AI-based therapy designed to help clinicians diagnose mental health issues. Chat-GPT uses natural language processing (NLP) to understand the patient’s conversations and provide personalized care and therapy.
Year 2021 face_with_colon_three This could be made into a smartphone device that could one day treat everything without the need for surgery or other ways that are not as safe.
Researchers are investigating potential uses for the cell reprogramming technology to treat brain disorders such as Alzheimer’s disease or autoimmune diseases.
In a remote part of the Amazon, anthropologists and neuroscientists are learning about life and health without an “embarrassment of riches.”
A major impediment to treating the deadly brain cancer glioblastoma has been that the most potent chemotherapy can’t permeate the blood-brain barrier to reach the aggressive brain tumor.
But now Northwestern Medicine scientists report results of the first in-human clinical trial in which they used a novel, skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy that was injected intravenously.
The four-minute procedure to open the blood-brain barrier is performed with the patient awake, and patients go home after a few hours. The results show the treatment is safe and well tolerated, with some patients getting up to six cycles of treatment.
Many people who have come close to death or have been resuscitated report a similar experience: Their lives flash before their eyes, memorable moments replay, and they may undergo an out-of-body experience, sensing they’re looking at themselves from elsewhere in the room. Now, a small study mapping the brain activity of four people while they were dying shows a burst of activity in their brains after their hearts stop.
The authors say the finding, published today in the, may explain how a person’s brain could replay conscious memories even after the heart has stopped. It “suggests we are identifying a marker of lucid consciousness,” says Sam Parnia, a pulmonologist at New York University Langone Medical Center who was not involved in the study.
Although death has historically been medically defined as the moment when the heart irreversibly stops beating, recent studies have suggested brain activity in many animals and humans can continue for seconds to hours. In 2013, for instance, University of Michigan neurologist Jimo Borjigin and team found that rats’ brains showed signs of consciousness up to 30 seconds after their hearts had stopped beating. “We have this binary concept of life and death that is ancient and outdated,” Parnia says.