Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of 7 years by approximately one-fifth.

Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding developmental processes. While not exact replicas of human organs, they offer significant insights.

The Siegert group at the Institute of Science and Technology Austria (ISTA) presents a new organoid model that reveals details of the developing nervous system’s response to viral infections, such as Rubella. This model could influence pharmaceutical testing, particularly benefiting drug safety for pregnant women.

Microglia are special cells in the human brain. Like a diligent ranger overseeing a forest and dealing with infestations and wildfires, microglia scan the brain environment for germs and initiate an anti-inflammatory response to remove them. They also monitor the quantity of neurons (nerve cells) and their connections to ensure optimal brain function in adulthood.

The new test could help identify which patients are most likely to benefit from new Alzheimer’s drugs. A newly developed blood test for Alzheimer’s disease not only helps confirm the presence of the condition but also provides information about how far the disease has progressed, according to resea

It took decades to notice.

Discover groundbreaking advancements in Alzheimer’s research, focusing on secretory dysfunction and innovative therapeutic approaches.