Scientists have used lipid nanoparticles to deliver CRISPR genome editing into the livers of mice, resulting in a 57% reduction of cholesterol levels.
The total amount of data generated worldwide is expected to reach 175 zettabytes (1 ZB equals 1 billion terabytes) by 2025. If 175 ZB were stored on Blu-ray disks, the stack would be 23 times the distance to the moon. There is an urgent need to develop storage technologies that can accommodate this enormous amount of data.
Understanding heat dissipation processes at nanoscale during cellular thermogenesis is essential to clarify the relationships between the heat and biological processes in cells and organisms. A key parameter determining the heat flux inside a cell is the local thermal conductivity, a factor poorly investigated both experimentally and theoretically. Here, using a nanoheater/nanothermometer hybrid made of a polydopamine encapsulating a fluorescent nanodiamond, we measured the intracellular thermal conductivities of HeLa and MCF-7 cells with a spatial resolution of about 200 nm. The mean values determined in these two cell lines are both 0.11 ± 0.04 W m−1 K−1, which is significantly smaller than that of water. Bayesian analysis of the data suggests there is a variation of the thermal conductivity within a cell.
Physicists from the University of Sussex have created what they called the tiniest microchips yet. The little microchips are made using graphene and other 2D materials and a form of “nano-origami.” The technique used in creating the tiny microchips marks the first time any researchers have been able to do this.
Researchers succeeded in making the tiny microchips by creating kinks in the structure of graphene to make the nanomaterial behave like a transistor. In their study, the team showed that when a graphene strip is crinkled in a specific way, it behaves like a microchip only about 100 times smaller than a conventional microchip. New construction methods are needed for microchips because traditional semiconducting technology is at the limit of what it can do.
The researchers believe that using the materials in their technique will make computer chips smaller and faster. The technology is dubbed “straintronics” and uses nanomaterials rather than electronics, allowing space for more chips inside a given device. The researchers believe everything we want to do with computers to speeding them up can be done by crinkling graphene.
Researchers believe this next generation of microchips could lead to computers and phones running thousands of times faster.
“” This type of wearable would be very helpful for people with underlying medical conditions to monitor their own health on a regular basis,” co-first author of the study Lu Yin said in a news release.
New wearable device converts body heat into electricity.
“It would also serve as a great tool for remote patient monitoring, especially during the COVID-19 pandemic when people are minimizing in-person visits to the clinic,” Yin, a nano-engineering doctoral student at the University of California, San Diego.
In addition to monitoring chronic conditions like diabetes and high blood pressure, as well as pinpointing the onset of sepsis, the patch could help predict people at risk of becoming severely ill with COVID-19.
Continue reading “New skin patch promises comprehensive health monitoring” »
Researchers from the Technical University of Denmark (DTU) have repurposed a component from a Microsoft Xbox 360 to develop a high-resolution large-volume nanoscale 3D printer with various applications in the medical sector.
The team took an optical pick-up unit (OPU) component from an Xbox 360 console to replace a conventional Stereolithography (SLA) optical system, in order to drastically simplify the SLA 3D printing system. With the OPU costing less than $5, the researcher’s solution could potentially increase the affordability of such equipment by thousands of pounds.
“With our 3D printer that can print micro and nanoscale 3D objects, we are able to go from tens of micrometers in printing resolution down to hundreds of nanometers without expensive specialized components,” said DTU PhD Student Tien-Jen Chang and research team member.
Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force—induced by ultrasound—can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.
Nanoscale doctors curing the body from within sounds like science fiction, but for Japanese research centre COINS, it’s a serious goal.
