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In episode 267 of the Stem Cell Podcast, we chat with Dr. Shankar Srinivas, a Professor of Developmental Biology in the Department of Physiology Anatomy and Genetics based in the Institute for Developmental and Regenerative Medicine at the University of Oxford. He is also a Zeitlyn Fellow and Tutor in Medicine at Jesus College. Using mouse and human embryos as model systems, his group looks at the control of patterning and morphogenesis during the establishment of the anterior-posterior axis, gastrulation, and early cardiogenesis. He discusses how tissues respond to forces during early development, characterizing cardiac progenitors, and training internationally.

Roundup Papers:
2:26 https://bit.ly/3yeD3ms.
7:14 https://bit.ly/4dKJ7nd.
19:06 https://go.nature.com/3V2SNSo.
27:10 https://go.nature.com/4dnC43H

38:40 Guest Interview.

#Cardiogenesis #DevelopmentalBiology.

Listen on Apple Podcasts: https://apple.co/2T8BhPA
Listen on Stitcher: https://bit.ly/3hGwsGA
Listen on Spotify: https://spoti.fi/3xFdENP

Official Website: https://stemcellpodcast.com/

As people age, their brains do, too. But if a brain ages prematurely, there is potential for age-related diseases such as mild cognitive impairment, dementia, or Parkinson’s disease. If “brain age” could be easily calculated, then premature brain aging could be addressed before serious health problems occur.

Researchers from Drexel University’s Creativity Research Lab have developed an artificial intelligence technique that can effectively estimate an individual’s brain age based on electroencephalogram (EEG) brain scans. The technology could help to make early, regular screening for degenerative brain diseases more accessible. The work is published in the journal Frontiers in Neuroergonomics.

Led by John Kounios, Ph.D., professor in Drexel’s College of Arts and Sciences and Creativity Research Lab director, the research team used a type of artificial intelligence called machine learning to estimate an individual’s brain age similar to the way one might guess another person’s age based on their physical appearance.

A new study has unveiled a surprising revelation: Women may need only half the amount of exercise as men to achieve similar benefits in terms of longevity. This groundbreaking research challenges conventional wisdom and underscores the importance of personalized approaches to physical fitness based on gender differences.

As the world grapples with rising concerns over sedentary lifestyles and their impact on health outcomes, these findings offer invaluable insights into optimizing exercise regimens for women.

The study also revealed that women who engage in regular physical activity may significantly extend their life spans. The findings, published in the Journal of the American College of Cardiology, shed light on the vital role of exercise in promoting longevity among women.

Mehmood Khaan opening the Rejuvenation Startup Summit with an outstanding speech on the state of longevity and the groundbreaking work that Hevolution is doing in funding scientists around the globe.

With the Rejuvenation Startup Summit in Berlin the Forever Healthy Foundation produced a great platform for founders and investors to meet and learn from and about eachother.

Crucial texts, many available in English for the first time, written before and during the Bolshevik Revolution by the radical biopolitical utopianists of Russian Cosmism.

Cosmism emerged in Russia before the October Revolution and developed through the 1920s and 1930s; like Marxism and the European avant-garde, two other movements that shared this intellectual moment, Russian Cosmism rejected the contemplative for the transformative, aiming to create not merely new art or philosophy but a new world. Cosmism went the furthest in its visions of transformation, calling for the end of death, the resuscitation of the dead, and free movement in cosmic space. This volume collects crucial texts, many available in English for the first time, by the radical biopolitical utopianists of Russian Cosmism.

Cosmism was developed by the Russian philosopher Nikolai Fedorov in the late nineteenth century; he believed that humans had an ethical obligation not only to care for the sick but to cure death using science and technology; outer space was the territory of both immortal life and infinite resources. After the revolution, a new generation pursued Fedorov’s vision. Cosmist ideas inspired visual artists, poets, filmmakers, theater directors, novelists (Tolstoy and Dostoevsky read Fedorov’s writings), architects, and composers, and influenced Soviet politics and technology. In the 1930s, Stalin quashed Cosmism, jailing or executing many members of the movement. Today, when the philosophical imagination has again become entangled with scientific and technological imagination, the works of the Russian Cosmists seem newly relevant.