Summary: Study finds a link between poor hydration in adults and an increased risk of chronic health conditions and advanced biological aging.
Source: NIH
Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine. .
New research in the journal Nature Aging takes a page from the field of renewable energy and shows that genetically engineered mitochondria can convert light energy into chemical energy that cells can use, ultimately extending the life of the roundworm C. elegans. While the prospect of sunlight-charged cells in humans is more science fiction than science, the findings shed light on important mechanisms in the aging process.
“We know that mitochondrial dysfunction is a consequence of aging,” said Andrew Wojtovich, Ph.D., associate professor of Anesthesiology and Perioperative Medicine and Pharmacology & Physiology at the University of Rochester Medical Center and senior author of the study.
“This study found that simply boosting metabolism using light-powered mitochondria gave laboratory worms longer, healthier lives. These findings and new research tools will enable us to further study mitochondria and identify new ways to treat age-related diseases and age healthier.”
Findings underline the importance of a strength-based rather than a deficit-based focus on aging and older adults.
What are the keys to “successful” or optimal aging? A new study followed more than 7,000 middle-aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.
They found that those who were female, married, physically active, and not obese and those who had never smoked, had higher incomes, and who did not have insomnia, heart disease or arthritis, were more likely to maintain excellent health across the study period and less likely to develop disabling cognitive, physical, or emotional problems.
Year 2011 face_with_colon_three
It was only a year ago that ACell’s “miracle powder” was sprinkled on amputated fingers and shown to stimulate the regeneration of fingertips. The world was both awed and skeptical of the powder’s regenerative power, touting that it would revolutionize regenerative medicine or calling it was quack science.
A fingertip is one thing. A thigh, quite another.
After losing most of his thigh muscle in a battlefield explosion, one marine was given a second chance when another such miracle powder caused much of his thigh to grow back. It’s not only a wonderful feel-good story, but demonstrating that the same substance can grow back different tissues suggests that we may have only seen a small part of its full regenerative potential.
“Decreased mitochondrial membrane potential is an attractive explanation for the complex dysfunctions of aging.”
University of Washington School of Medicine researchers’ experiment on C.elegans.
Roundworms, which have an average lifespan of just two to three weeks, are frequently used in aging studies… More.
National Science Foundation.
As part of their research on aging, the team is interested in learning how to modulate mitochondrial activity directly. The energy centers inside living cells are called mitochondria. Among their numerous essential roles, they are vital for cellular respiration and energy production, as per the release.
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Although we’ve been socialized to accept death as an inevitability, and live our lives knowing that its looming shadow will one day catch up with us, many of us might never really come to terms with it. Throughout our evolution, we’ve come up with ideas, beliefs and theories that attempt to shine a light deep into the cold, dark abyss of death to give ourselves a hope of continued living and everlasting existence. Could we really stop our cells from aging? If you could, would you want to be immortal?
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Tardigrades have competition in the realm of microscopic and incredibly sturdy beasties. Like tardigrades, Bdelloid rotifers can also survive drying, freezing, starving, and even low-oxygen conditions. Now, scientists report that they revived some of these rotifers after having been frozen in Siberian permafrost for at least 24,000 years.
The incredible observations are reported in the journal Current Biology. The researchers took samples of permafrost about 3.5 meters (11.5 feet) deep and slowly warmed the sample, which led to the resurrection of several microscopic organisms including these tiny little animals.
“Our report is the hardest proof as of today that multicellular animals could withstand tens of thousands of years in cryptobiosis, the state of almost completely arrested metabolism,” co-author Stas Malavin of the Soil Cryology Laboratory at the Institute of Physicochemical and Biological Problems in Soil Science in Pushchino, Russia, said in a statement.
The whole interview is good and informative but starts with Sinclair commenting that at the moment he thinks living to 150 is possible in our lifetimes but not immortality. But given that, I’m 51. If I’m going to live potentially another century the technology will get better and better in that century and I would fully expect to life spans to become what we want rather than what we have to accept.
In this Ask Me Anything session, David and Peter discuss the latest age-reversal breakthroughs, getting approval from the FDA, and the possibility of living forever.
David Sinclair is a biologist and academic known for his expertise in aging and epigenetics. Sinclair is a genetics professor and the Co-Director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research. He’s been included in Time100 as one of the 100 Most Influential People in the World, and his research has been featured all over the media. Besides writing a New York Times Best Seller, David has co-founded several biotech companies, a science publication called Aging, and is an inventor of 35 patents.
Read David’s book, Lifespan: Why We Age-and Why We Don’t Have To: https://a.co/d/85H3Mll.
This episode is brought to you by Levels: real-time feedback on how diet impacts your health. https://levels.link/peter.
Consider a journey to optimize your mind and body by visiting http://mylifeforce.com/peter.
Read the Tech Blog: https://www.diamandis.com/blog.