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Artificial intelligence is able to identify women who have an elevated risk of developing breast cancer several years before it is diagnosed, the Norwegian Institute of Public Health (FHI) said on Tuesday.
Imagine smartphones that can diagnose diseases, detect counterfeit drugs or warn of spoiled food. Spectral sensing is a powerful technique that identifies materials by analyzing how they interact with light, revealing details far beyond what the human eye can see.
Traditionally, this technology required bulky, expensive systems confined to laboratories and industrial applications. But what if this capability could be miniaturized to fit inside a smartphone or wearable device?
Researchers at Aalto University in Finland have combined miniaturized hardware and intelligent algorithms to create a powerful tool that is compact, cost-effective, and capable of solving real-world problems in areas such as health care, food safety and autonomous driving. The research is published in the journal Science Advances.
Researchers found that lycopene enhances BDNF expression, a key protein involved in brain health, which appears to be suppressed in depression.
Lycopene’s Potential as an Antidepressant
Lycopene, a natural compound found in plants, may have antidepressant effects, according to emerging research. A new study published on January 22 in Food Science & Nutrition explores how lycopene influences brain function to counteract symptoms of depression.
A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of dilated cardiomyopathy, a pathological enlargement of the heart chambers, researchers at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now identified a cause: a low level of the enzyme Ubiquitin-specific peptidase 5 (USP5) leads to an accumulation of Ubiquitin in heart muscle cells and the formation of protein aggregates, which trigger heart diseases. Increasing USP5 levels in heart muscle cells protects the heart from harmful degradation processes, offering a perspective for new therapies.
Dilated cardiomyopathy is a pathological enlargement of one or both heart chambers, including the atria. The resulting restriction of heart function is caused by structural damage to heart muscle cells. The consequence is heart failure, which can lead to death without a heart transplant. Existing therapeutic options can usually not stop or reverse the progression of the disease.
In search of new therapeutic approaches, researchers from the department of Thomas Braun at the Max Planck Institute for Heart and Lung Research have investigated the molecular processes of protein degradation in heart muscle cells. Yvonne Eibach and Silke Kreher, both first authors of the study published in Science Advances, together with their research partners, discovered disturbances in the process that serves the disposal of defective or no longer needed proteins.
A major international study reveals that most people with cardiovascular disease.
Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and blood vessels, including coronary artery disease, heart attack, stroke, and hypertension. These conditions are primarily driven by atherosclerosis, a process where plaque builds up in the arterial walls, leading to narrowed or blocked arteries. Risk factors include smoking, unhealthy diet, lack of exercise, obesity, and genetic predisposition. CVD remains a leading cause of global mortality, emphasizing the importance of lifestyle changes, medical interventions, and preventive measures in managing and reducing the risk of heart-related illnesses.
The future of medicine may very well lie in the personalization of health care—knowing exactly what an individual needs and then delivering just the right mix of nutrients, metabolites, and medications, if necessary, to stabilize and improve their condition. To make this possible, physicians first need a way to continuously measure and monitor certain biomarkers of health.
To that end, a team of Caltech engineers has developed a technique for inkjet printing arrays of special nanoparticles that enables the mass production of long-lasting wearable sweat sensors. These sensors could be used to monitor a variety of biomarkers, such as vitamins, hormones, metabolites, and medications, in real time, providing patients and their physicians with the ability to continually follow changes in the levels of those molecules.
Wearable biosensors that incorporate the new nanoparticles have been successfully used to monitor metabolites in patients suffering from long COVID and the levels of chemotherapy drugs in cancer patients at City of Hope in Duarte, California.
If you have ever had your blood drawn, whether to check your cholesterol, kidney function, hormone levels, blood sugar, or as part of a general checkup, you might have wondered why there is not an easier, less painful way.
Now there might be. A team of researchers from Caltech’s Cherng Department of Medical Engineering has unveiled a new wearable sensor that can detect in human sweat even minute levels of many common nutrients and biological compounds that can serve as indicators of human health.
The sensor technology was developed in the lab of Wei Gao, assistant professor of medical engineering, Heritage Medical Research Institute investigator, and Ronald and JoAnne Willens Scholar. For years, Gao’s research has focused on wearable sensors with medical applications, and this latest work represents the most precise and sensitive iteration yet.
Tiny plastic particles may accumulate at higher levels in the human brain than in the kidney and liver, with greater concentrations detected in postmortem samples from 2024 than in those from 2016, suggests a paper published in Nature Medicine. Although the potential implications for human health remain unclear, these findings may highlight a consequence of rising global concentrations of environmental plastics.
The amount of environmental plastic nano-and microparticles, which range in size from as small as 1 nanometer (one billionth of a meter) up to 500 micrometers (one millionth of a meter) in diameter, has increased exponentially over the past 50 years. However, whether they are harmful or toxic to humans is unclear. Most previous studies used visual microscopic spectroscopy methods to identify particulates in human tissues, but this is often limited to particulates larger than 5 micrometers.
Researcher Matthew Campen and colleagues used novel methods to analyze the distribution of micro-and nanoparticles in samples of liver, kidney, and brain tissues from human bodies that underwent autopsy in 2016 and 2024. A total of 52 brain specimens (28 in 2016 and 24 in 2024) were analyzed.
As people age, their memory and thinking skills naturally decline. Approximately 15% of older adults experience mild cognitive impairment, a major risk factor for dementia and other forms of dementia such as Alzheimer’s disease.
Since cognitive decline and dementia are growing public health concerns, scientists are working to better understand the risk factors and find ways to reduce them. One emerging area of research suggests that oral health may play a role in brain health.
Now, a new study suggests that the bacteria living in the mouth may influence cognitive function as people age, with some harmful bacteria possibly contributing to the development of dementia and Alzheimer’s disease.