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Category: health – Page 40

Dr. Ana Diaz Artiles: “When we’re upright, a large part of our fluids are stored in our legs, but in microgravity we get a redistribution of fluids into the upper body.”

What physiological effects can extended periods of microgravity have on the human eye? This is what a recent study published in npj Microgravity hopes to address as a team of researchers investigated how the shifting of fluids under microgravity conditions could lead to eye vessel alterations. This study holds the potential to help space agencies, researchers, and the public better understand the short-and long-term physiological effects of microgravity, specifically with more humans traveling beyond Earth’s gravity on commercial spaceflights.

“When we experience microgravity conditions, we see changes in the cardiovascular system because gravity is not pulling down all these fluids as it typically does on Earth when we are in an upright position,” said Dr. Ana Diaz Artiles, who is an assistant professor in the Department of Aerospace Engineering at Texas A&M University and a co-author on the study. “When we’re upright, a large part of our fluids are stored in our legs, but in microgravity we get a redistribution of fluids into the upper body.”

For the study, the researchers analyzed how lower body negative pressure (LBNP), which involves the transferring of fluids from the upper body to the lower body, could potentially be used to counteract what’s known as Spaceflight Associated Neuro-ocular Syndrome (SANS), which, while still not well understood, often results in physiological changes in the eyes, also called ocular prefusion pressure (OPP). Using 24 participants, 12 male and 12 female, the researchers subjected the participants to treatments inside an LBNP chamber to ascertain the effects on counteracting OPP.

Continue reading “Impact of Space Flight on Human Health: A Focus on the Eye” | >

Researchers at the National Institutes of Health (NIH) have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to standard treatments. The five-drug combination targets multiple molecular pathways that diffuse large B-cell lymphoma (DLBCL) tumors use to survive.

In a clinical trial at NIH’s National Cancer Institute (NCI), researchers tested the combination of venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide (called ViPOR) in 50 patients with DLBCL, the most common type of lymphoma. The treatment shrank tumors substantially in 26 of 48 (54%) evaluable patients, with 18 (38%) of those patients’ tumors disappearing entirely, known as a complete response. At two years, 36% of all patients were alive and 34% were free of disease. These benefits were seen mainly in people with two specific subtypes of DLBCL.

The findings were published June 20, 2024, in the New England Journal of Medicine.

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Groundbreaking maps reveal the complex gene regulation in brains with and without mental disorders, enhancing the understanding of mental illnesses and potential treatments.

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain’s biological pathways and cellular functions. The research, supported by the National Institutes of Health (NIH), used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple brain-related disorders.

“These groundbreaking findings advance our understanding of where, how, and when genetic risk contributes to mental disorders such as schizophrenia, post-traumatic stress disorder, and depression,” said Joshua A. Gordon, M.D., Ph.D., director of NIH’s National Institute of Mental Health (NIMH). “Moreover, the critical resources, shared freely, will help researchers pinpoint genetic variants that are likely to play a causal role in mental illnesses and identify potential molecular targets for new therapeutics.”

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Science and Technology: Some robots could be “eaten” so they could walk around inside the body and perform tests or surgeries from the inside out; or administer medications.

Robots made of several nanorobots joined together could assemble and reassemble themselves inside the body even after being…

Robots and food have long been distant worlds: Robots are inorganic, bulky, and non-disposable; food is organic, soft, and biodegradable. Yet, research that develops edible robots has progressed recently and promises positive impacts: Robotic food could reduce , help deliver nutrition and medicines to people and animals in need, monitor health, and even pave the way to novel gastronomical experiences.

But how far are we from having a fully edible robot for lunch or dessert? And what are the challenges? Scientists from the RoboFood project, based at EPFL, address these and other questions in a perspective article in the journal Nature Reviews Materials.

Continue reading “A fully edible robot could soon end up on our plate, say scientists” | >

SpinLaunch was founded in 2014, and its leadership team has since raised tens of millions of dollars in funding. The company has been working with NASA, Airbus, and Cornell University, launching some of their equipment as part of testing. The tech has so far endured 10,000 Gs, “10,000 times the force of Earth’s gravity,” all per the Space.com report.

If SpinLaunch’s concept proves reliable, it could eliminate the loads of fuel that is burned to launch spacecraft. In 2016, Business Insider noted that SpaceX’s Falcon 9 rocket used more than 900,000 pounds of propellant for each liftoff, for reference. The fuel efficiency may have improved some since then.

CBC News reports that a growing number of launches are starting to draw scrutiny, particularly for ozone layer health. The barrier protects us from some of the sun’s harmful radiation.

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Researchers have discovered sex-specific differences in the nerve cells that generate pain, paving the way for personalized pain management treatments based on patient sex.

Research indicates that men and women experience pain differently, but the reasons behind this have remained unclear. A new study from the University of Arizona Health Sciences, published in the journal BRAIN, has now identified functional sex differences in nociceptors, the specialized nerve cells that produce pain.

The findings support the implementation of a precision medicine-based approach that considers patient sex as fundamental to the choice of treatment for managing pain.

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Future missions to Mars were not ruled out, though the scientists said that measures to protect the kidneys would need to be developed to avoid serious harm to astronauts. Methods of recovery could also be introduced onboard spacecraft, such as dialysis machines.

“We know what has happened to astronauts on the relatively short space missions conducted so far, in terms of an increase in health issues such as kidney stones,” said Dr Keith Siew, first author of the study from the London Tubular Centre, based at the UCL Department of Renal Medicine.

What we don’t know is why these issues occur, nor what is going to happen to astronauts on longer flights such as the proposed mission to Mars. If we don’t develop new ways to protect the kidneys, I’d say that while an astronaut could make it to Mars they might need dialysis on the way back.

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Most distant spacecraft, #Voyager1, is now returning data from all four science instruments for the first time following a technical issue last November.

NASA’s Voyager 1 spacecraft is conducting normal science operations for the first time following a technical issue that arose in November 2023.

The team partially resolved the issue in April when they prompted the spacecraft to begin returning engineering data, which includes information about the health and status of the spacecraft. On May 19, the mission team executed the second step of that repair process and beamed a command to the spacecraft to begin returning science data. Two of the four science instruments returned to their normal operating modes immediately. Two other instruments required some additional work, but now, all four are returning usable science data.

The four instruments study plasma waves, magnetic fields, and particles. Voyager 1 and Voyager 2 are the only spacecraft to directly sample interstellar space, which is the region outside the heliosphere — the protective bubble of magnetic fields and solar wind created by the Sun.

Continue reading “Voyager 1 Returning Science Data From All Four Instruments” | >