A new preclinical study has found exposure to nanoplastics may contribute to the rapid progression of Alzheimer’s disease and subsequent spread from the brain to other key organs such as the liver, heart and gut.
The research, “Cerebral to Systemic Representations of Alzheimer’s Pathogenesis Stimulated by Polystyrene Nanoplastics,” is published in the journal Environment & Health.
The study, co-led by Monash University and South China University of Technology, investigated how environmental-level polystyrene nanoplastic exposure influences the progression of Alzheimer’s disease from the brain to other parts of the body. Studies in mice revealed that nanoplastic-induced neurological damage is not confined within the brain, but expands systemically through the gut–liver–brain axis.
NEW YORK, Aug. 5, 2025 /PRNewswire/ — A new study provides the first visual evidence showing that brain circuits in living animals can be activated by ultrasound waves projected into specific patterns (holograms).
Led by scientists at NYU Langone Health and at the University of Zurich and ETH Zurich in Switzerland, the study describes a system that combines sources of ultrasound waves and a fiber scope connected to a camera to visualize in study mice brain targets that are directly activated by the sound. This lays the groundwork, the study authors say, for a new way to treat neurological diseases and mental health disorders from outside of the body.
Already, there are applications approved by the Food and Drug Administration and designed to reduce tremor symptoms seen in Parkinson’s disease, using intense sound waves to kill brain cells called neurons within neural pathways linked to tremors. Rather than kill neurons, the lower-intensity ultrasound waves used in the current work can temporarily activate them, the researchers say. The resulting effects can be widespread as neurons relay messages to other neurons within their circuits and between interconnected neuronal circuits.
Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects, yet they carry the risk of serious adverse effects such as respiratory depression and drug dependence. For this reason, Japan has strict regulations in place to ensure that these medications are prescribed only by authorized physicians.
In the United States, the opioid OxyContin was once frequently prescribed, triggering a surge in the misuse of synthetic opioids such as fentanyl. As a result, the number of deaths caused by opioid overdose surpassed 80,000 in 2023, escalating into a national public health crisis now referred to as the “opioid crisis.”
Opioids may soon have a rival, however. A team of researchers at Kyoto University has recently discovered a novel analgesic, or pain reliever, that exerts its effect through an entirely different mechanism. Clinical development of their drug ADRIANA is currently underway as part of an international collaborative effort.
Plastic pollution is a “grave, growing and under-recognized danger” to health that is costing the world at least $1.5 trillion a year, experts warned in a report on Monday.
The new review of the existing evidence, which was carried out by leading health researchers and doctors, was published one day ahead of fresh talks opening in Geneva aiming to seal the world’s first treaty on plastic pollution.
“Plastics cause disease and death from infancy to old age and are responsible for health-related economic losses exceeding US$1.5 trillion annually,” said the review in The Lancet medical journal.
Health officials are sending a warning to residents in Gulf Coast states after eight people are dead from the flesh-eating bacteria called Vibrio vulnificus.
On Thursday, July 31, the Louisiana Department of Heath confirmed 17 cases of the flesh-eating bacteria this year, all of which resulted in hospitalizations. Additionally four cases resulted in death. About 75% of those cases were due to wound infection via seawater.
Additionally, the Florida Department of Health confirmed 13 cases and four deaths from Vibrio this year. Both Mississippi and Alabama have also reported single cases, neither fatal.
A new Stanford-led study sheds light on “an emerging psychological health crisis” that disproportionately affects girls. Published July 30 in The Lancet Planetary Health, the study is among the first to quantify how repeated climate stressors impact the psychological well-being and future outlook of adolescents in low-resource settings.
Researchers from Stanford’s schools of Medicine, Law, and Sustainability partnered with health experts in Bangladesh to survey more than 1,000 teenagers and conduct focus groups across two regions with starkly different flood exposure.
“What we found really lifts the voices of frontline adolescents —a group whose perspectives and health outcomes are so rarely investigated and communicated,” said lead author Liza Goldberg, an incoming Earth system science Ph.D. student in the Stanford Doerr School of Sustainability.
The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass. Finding a protein that isn’t in this top 10 is a bit like looking for Waldo if only one rendition of the character remained in a collection of every “Where’s Waldo” comic ever produced.
This range of disparity in protein concentration is termed dynamic range, and it makes it more difficult for scientists to identify less-abundant proteins and their matching receptors.
Scientists published findings in Nature Communications demonstrating a strategy for identifying less-abundant proteins that bind with a specific type of receptor termed an endocytic lectin, and namely the mannose receptor Mrc1 (also known as CD206 and MMR). This approach enabled the research team to uncover hundreds of binding partners that together predicted Mrc1’s roles in our health.