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Exploring Mitochondrial Bioenergetics, Optogenetics, Human Health And Aging — Dr. Brandon Berry, Ph.D., University of Washington.
Dr. Brandon Berry, Ph.D. (https://halo.dlmp.uw.edu/people/brandon-berry/) is a postdoctoral researcher in the Kaeberlein Laboratory at University of Washington where his research focuses on how aging and metabolism are linked.
For the first time, researchers from Tel Aviv University have developed a genome-scale technology that makes it possible to reveal the role of genes and traits in plants previously hidden by functional redundancy.
The researchers point out that since the agricultural revolution, man has improved plant varieties for agricultural purposes by creating genetic diversity. But until this recent development, it was only possible to examine the functions of single genes, which make up only 20% of the genome. For the remaining 80% of the genome, made up of genes grouped in families, there was no effective way, on the large scale of the whole genome, to determine their role in the plant.
As a result of this unique development, the team of researchers managed to isolate and identify dozens of new features that had been overlooked until now. The development is expected to revolutionize the way agricultural crops are improved as it can be applied to most crops and agricultural traits, such as increased yield and resistance to drought or pests.
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Researchers at the University at Albany’s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium. The method improves the biostability of the structures, making them more useful and reliable in a range of applications. The work appears in the journal Small this month.
When we think of DNA, the first association that comes to mind is likely genetics—the double helix structure within cells that houses an organism’s blueprint for growth and reproduction. A rapidly evolving area of DNA research is that of DNA nanostructures—synthetic molecules made up of the same building blocks as the DNA found in living cells, which are being engineered to solve critical challenges in applications ranging from medical diagnostics and drug delivery to materials science and data storage.
“In this work, we assembled DNA nanostructures without using magnesium, which is typically used in this process but comes with challenges that ultimately reduce the utility of the nanostructures that are produced,” said Arun Richard Chandrasekaran, corresponding author of the study and senior research scientist at the RNA Institute.
Summary: Researchers discovered sequence variants in the gene ABCC9 that influence voice pitch.
Utilizing speech recordings from nearly 13,000 Icelanders and corresponding genomic data, the scientists identified common ABCC9 variants associated with higher voice pitch in both men and women. Additionally, these variants were linked to higher pulse pressure, revealing intriguing connections between voice pitch and health.
The study also uncovered a heritable component in vowel acoustics, enhancing our understanding of the human vocal system.
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We often discuss cybernetic, genetic engineering, artificial intelligence, and hybrids of them, but what truly is synthetic life? And what is it like?
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Continue reading “Should we take evolution into our own hands and become transhuman?” »
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Continue reading “Taurine Deficiency As A Driver Of Aging: What’s My Data (Youthful Or Aged)?” »
In a paper published in Science Advances, an international team led by deCODE genetics, a subsidiary of Amgen, reveals the discovery of sequence variants in the gene ABCC9 that influence the pitch of voices.
Speaking is one of the most characteristic human behaviors, and yet the genetic underpinnings of voice and speech are largely unknown. In the first study of its kind, the scientists combined speech recordings from almost 13,000 Icelanders with data, in the sequence of the genome, to search for common variants in ABCC9 that are associated with a higher-pitched voice.
Continue reading “Study reveals first genetic locus for voice pitch” »
