A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say.
Category: genetics – Page 8
RNA is the molecule that reads the genetic information stored in DNA. It’s critical for the proper functioning of cells, and in a new study published in Nature Communications, University of California, Irvine scientists have discovered a way of tagging RNA with a glowing bioluminescent molecule that allows them to track RNA in real time as it moves throughout the body. The work promises to help scientists better understand everything from the way viruses propagate to how memories form in the brain.
Researchers unveil how biological sex influences brain aging, revealing genetic, hormonal, and molecular mechanisms behind cognitive resilience and decline.
Throughout history, humanity has spun horrifying tales of sapient species beyond our own. From ghastly subhuman creatures dwelling in decrepit subterranean lairs to ghoulish humanoids bent on destruction, these lores have delighted and terrified us in equal measure. The medieval period was rife with legends of menacing beings lurking in the shadows, while centuries later, the Industrial Revolution ushered in scientific breakthroughs in anatomy and genetics. With this came a new question: could other sapient beings truly exist?
ECFG 17
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It is pleasure for us to bring the ECFG conference to the island of Ireland from mainland Europe, we believe the conference will be a great scientific and social success.
We believe that Ireland is an ideal location which is accessible with low fare economic flights both from Europe and America and more than 20,000 hotel bed capacity for potential participants.
There will be a rich repertoire of research highlights from early, mid and advanced career researchers in the field of fungal genetics and biology. Our venue, the Convention Centre Dublin, is in a perfect location in the heart of Dublin city.
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Summary: Researchers have developed an AI model that accurately predicts gene activity in any human cell, providing insights into cellular functions and disease mechanisms.
Trained on data from over 1.3 million cells, the model can predict gene expression in unseen cell types with high accuracy. It has already uncovered mechanisms driving a pediatric leukemia and may help explore the genome’s “dark matter,” where most cancer mutations occur.
Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices.
The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can simultaneously and independently address different genetic diseases in the same cell.
In a new paper in Nature Communications, researchers in the Center for Precision Engineering for Health (CPE4H) at the University of Pennsylvania School of Engineering and Applied Science (Penn Engineering) describe minimal versatile genetic perturbation technology (mvGPT).
Summary: While humans share over 95% of their genome with chimpanzees, our brains are far more complex due to differences in gene expression. Research shows that human brain cells, particularly glial cells, exhibit higher levels of upregulated genes, enhancing neural plasticity and development.
Oligodendrocytes, a glial cell type, play a key role by insulating neurons for faster and more efficient signaling. This study underscores that the evolution of human intelligence likely involved coordinated changes across all brain cell types, not just neurons.
Outdated BIOS firmware in Illumina iSeq 100 allows attackers to disable devices or install malware, threatening critical genetic research and vaccine.