Long-lasting leukemia remission prompts doctors to call CAR-T cell therapy a ‘cure’ for some.
Category: genetics – Page 244
Dr Katcher’s E5 Experiment
Posted in biotech/medical, genetics, health
VICE.
BitMouseDAO has exactly two investors and almost no money, but they do have a wild idea.
Researchers from the University of Illinois developed GPU-accelerated software to simulate a cell that metabolizes and grows like a living cell.
Every living cell contains its own bustling microcosm, with thousands of components responsible for energy production, protein building, gene transcription and more.
Scientists at the University of Illinois at Urbana-Champaign have built a 3D simulation that replicates these physical and chemical characteristics at a particle scale — creating a fully dynamic model that mimics the behavior of a living cell.
Published in the journal Cell, the project simulates a living minimal cell, which contains a pared-down set of genes essential for the cell’s survival, function and replication. The model uses NVIDIA GPUs to simulate 7,000 genetic information processes over a 20-minute span of the cell cycle – making it what the scientists believe is the longest, most complex cell simulation to date.
What are biomarkers? They are medical signals that can measure health in an accurate and reproducible way. Common examples include blood pressure readings, heart rate, and even genetic test results.
Modern digital devices measure several health parameters. Fitbit trackers use sensors such as accelerometers to tell how many steps we’ve taken in a day or how fast we’ve been walking. When can such novel health measures function as medical biomarkers?
The measures must be objective, quantifiable, and reproducible. Additionally, scientific evidence needs to show that the health attribute measured by the device maps consistently and accurately to a clinical outcome. For example, voice signals from a smartphone’s microphone can detect mild cognitive impairment due to Alzheimer’s disease. World War II, commanders and troops communicated using hand-sent Morse codes. To avoid capture by enemies, telegraph operators had to remain anonymous. Any clues about operator identity or location could influence battle outcomes.
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The Lifeboat Foundation is a nonprofit nongovernmental organization dedicated to encouraging scientific advancements while helping humanity survive existential risks and possible misuse of increasingly powerful technologies, including genetic engineering, nanotechnology, and robotics/AI, as we move towards the Singularity.
Lifeboat Foundation is pursuing a variety of options, including helping to accelerate the development of technologies to defend humanity, such as new methods to combat viruses, effective nanotechnological defensive strategies, and even self-sustaining space colonies in case the other defensive strategies fail.
We believe that, in some situations, it might be feasible to relinquish technological capacity in the public interest (for example, we are against the U.S. government posting the recipe for the 1918 flu virus on the internet). We have some of the best minds on the planet working on programs to enable our survival. We invite you to join our cause!
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A platform for single-molecule measurement of binding kinetics & enzyme activity.
The first molecular electronics chip has been developed, realizing a 50-year-old goal of integrating single molecules into circuits to achieve the ultimate scaling limits of Moore’s Law. Developed by Roswell Biotechnologies and a multi-disciplinary team of leading academic scientists, the chip uses single molecules as universal sensor elements in a circuit to create a programmable biosensor with real-time, single-molecule sensitivity and unlimited scalability in sensor pixel density. This innovation, appearing this week in a peer-reviewed article in the Proceedings of the National Academy of Sciences (PNAS), will power advances in diverse fields that are fundamentally based on observing molecular interactions, including drug discovery, diagnostics, DNA
DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).