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Category: genetics – Page 244

Knocking out transposon promoter leads to pup death in mice; similar promoters found in many mammals.

Nearly half of our DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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Integrated And Cross-Disciplinary Research Focused on Diagnosing, Treating And Curing Cancers — Dr. Antonio Giordano MD, PhD, President & Founder, Sbarro Health Research Organization.

Dr. Antonio Giordano, MD, Ph.D., (https://www.drantoniogiordano.com/) is President and Founder of the Sbarro Health Research Organization (https://www.shro.org/), which conducts research to diagnose, treat and cure cancer, but also has diversified into research beyond oncology, into the areas of cardiovascular disease, diabetes and other chronic illnesses.

Dr. Giordano is also a Professor of Molecular Biology at Temple University in Philadelphia, a ‘Chiara fama’ Professor in the Department of Pathology & Oncology at the University of Siena, Italy, and Director of the Sbarro Institute for Cancer Research and Molecular Medicine, and the Center for Biotechnology, at Temple’s College of Science & Technology.

Continue reading “Dr. Antonio Giordano, MD, Ph.D. — President and Founder, Sbarro Health Research Organization” | >

For most of the time since the first description of multiple sclerosis (MS) in 1,868 the causes of this disabling disease have remained uncertain. Genes have been identified as important, which is why having other family members with MS is associated with a greater risk of developing the disease.

A recent study my colleagues and I conducted found that several types of infection during the teenage years are associated with MS after age 20. Our study didn’t investigate whether people who are more likely to have genetic risks for MS were also more likely to have worse infections.

This might explain why people with MS also have more infections that need hospital treatment.

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Latest scientific findings suggest the ancestral Native American population does not originate in Japan, as believed by many archaeologists.

A widely accepted theory of Native American origins coming from Japan has been attacked in a new scientific study, which shows that the genetics and skeletal biology “simply does not match-up.”

The findings, published on October 12 2021, in the peer-reviewed journal PaleoAmerica, are likely to have a major impact on how we understand Indigenous Americans’ arrival to the Western Hemisphere.

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Talking about RejuvenateBio starts at 20:30. Mentions there are 300 known genes concerning human aging and 45 of those have been tested in mice with what sounds like success.

Wow! Where do I start. I woke up and seen Dr. George Church on Bloomberg news. They was discussing a new biotech startup company called Rejuvenate Bio. A life extension company that seeks to reverse aging in dogs. Then apply that knowledge to humans. I ask Dr. Church about what he thinks is the cause of aging. t. Dr. Church thinks its a genetic reason why we age. Dr. Church is a cofounder of a company called Colossal is a company that wants to create a hybrid between the east asian elephant and the woolly mammoth. The purpose of doing this is to fight climate change and prevent the extinction of the east asian elephant.

https://www.rejuvenatebio.com/

Continue reading “Harvard University professor geneticist Dr. George Church stops by the Institute” | >

The structural integrity of the brain’s white matter as measured with an advanced MRI technique is lower in cognitively normal people who carry a genetic mutation associated with Alzheimer’s disease than it is in non-carriers, according to a study in Radiology. Researchers said the findings show the promise of widely available imaging techniques in helping to understand early structural changes in the brain before symptoms of dementia become apparent.

People who carry the autosomal dominant Alzheimer disease (ADAD) mutation have a higher risk of Alzheimer’s disease, a type of dementia that affects about one in nine people in the United States. The mutation is linked to a buildup of abnormal protein called amyloid-beta in the brain that affects both the gray matter and the signal-carrying white matter.

“It’s thought that the amyloid deposition in the gray matter could disrupt its function, and as a result the white matter won’t function correctly or could even atrophy,” said study lead author Jeffrey W. Prescott, M.D., Ph.D., neuroradiologist at the MetroHealth Medical Center in Cleveland.

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ORF Genetics in Iceland is growing 100,000 genetically engineered barley plants in a greenhouse measuring over 22 square feet (2 sq m) to create lab-grown meat.

This cutting-edge approach has the potential to lower prices, eliminate reliance on live animals in the lab-grown meat sector, and speed up the scaling-up process, according to BBC. And, with the fact that meat accounts for nearly 60 percent of all greenhouse gases from food production in mind, such a development could have far-reaching implications in the fight against climate change.

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“Lower levels of DHA are associated with inflammation, cardiovascular and brain disorders, such as depression, which are all linked to migraine risk.”

Professor Nyholt said LPE(20:4) was a chemical compound that blocked the production of an anti-inflammatory molecule called anandamide.

Summary: Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.

Source: Queensland University of Technology

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Researchers in Iceland are growing over 100,000 genetically modified barley plants inside a greenhouse for a very unusual purpose: creating lab-grown meat, the BBC reports.

The altered barley gets harvested and purified to extract “growth factor” proteins, which, in turn, can be used to cultivate lab-grown meat — an innovation that could make the lab-grown meat industry rely even less on live animals in the future.

The company behind the greenhouse, ORF Genetics, is growing the biogenetically engineered barley over 22,000 square feet using high-tech hydroponic cultivation methods.

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