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In this episode, I talk to world-renowned biologist David Sinclair about aging and longevity. David rejects the notion that the deterioration of health is a natural part of growing old and asserts that aging is a disease itself that we need to reverse. But how will a reset of our biological clocks affect our interactions, responses to adversity, morality, and how we live our lives? We discuss the ethical implications of limitless lifespans and also touch on the topics of death, evolution, genetics, medicine, and data tracking.

Bio.
Dr. David Sinclair is a professor in the department of genetics and co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School and co-founder of the scientific journal Aging. He is best known for his work on understanding why we age and how to slow its effects. In addition to being a co-founder of several biotechnology companies, he’s the author of the book Lifespan: Why We Age – and Why We Don’t Have To. Dr. Sinclair was listed by TIME magazine as one of the “100 most influential people in the world”.

Website: sinclair.hms.harvard.edu.

Twitter: @davidasinclair.

Good news, everyone! We’ve been selected for a Gitcoin grant partnership to help democratize and incentivize future funding for our upcoming feature-length film’s development.

Gitcoin grants operate with crypto under a system known as “Quadratic Funding.” In other words, amounts are important, but the number of people donating also helps tremendously by boosting matching funds from a pre-established pool. So even small donation amounts can be hugely helpful. Therefore, any donation we receive from you will then be matched at an ever-increasing amount with each new donation.

We’re very excited to see where this takes us and if you’d like to contribute to the financing with more bang for your buck, check out the link below and start donating!


“The Last Generation to Die” is a cinematic quality full feature film on longevity. It’s a drama set in the future that examines the estranged relationship of two generations on the cusp of the end of aging and the ultimate merging of science and nature that will usher humanity into the next stage of evolution.

Our hunter-gatherer ancestors are huddled around a campfire when they suddenly hear the nearby bushes rustling. They have two options: investigate if the movement was caused by small prey such as a rabbit, or flee, assuming there was a predator such as a saber-tooth tiger. The former could lead to a nutritious meal, while the latter could ensure survival. What call do you think our ancestors would have made?

Evolution ensured the survival of those who fled the scene on the margin of safety rather than those who made the best decision by analyzing all possible scenarios. For thousands of years, humans have made snap decisions in fight-or-flight situations. In many ways, the human race learned to survive by jumping to conclusions.

“In modern context, such survival heuristics become myriad cognitive biases,” said Eric Colson, Chief Algorithms Officer at Stitch Fix. Let’s look at the most common biases or shortcut decisions that influence organizational leaders and how decision intelligence can come to their rescue.

Are viruses alive or are they lifeless packages of protein and nucleic acid?
Watch the Q&A: https://youtu.be/-LUQTjdHYNo.
Carl’s book “Life’s Edge: The Search for What It Means to Be Alive” is available now — https://geni.us/zimmer.

Countless scientists around the world study life, and yet they can’t really agree on what it is. Join New York Times columnist Carl Zimmer as he explores the boundaries of life, encountering viruses and other strange residents of the borderlands.

Carl Zimmer is the author of fourteen books about science. Zimmer’s column “Matter” appears each week in the New York Times. His writing has earned a number of awards, including the Stephen Jay Gould Prize, awarded by the Society for the Study of Evolution. His book, She Has Her Mother’s Laugh, won the 2019 National Academies Communication Award. The Guardian named it the best science book of 2018.

Zimmer is a familiar voice on radio programs such as Radiolab and professor adjunct at Yale University. He is, to his knowledge, the only writer after whom both a species of tapeworm and an asteroid have been named.

Imagine, if you will, that future humans manage to travel to other worlds and find… more humans.

According to one University of Cambridge astrobiologist, that scenario may be more likely than you’d think.

In a new interview with the BBC’s Science Focus magazine, an evolutionary palaeobiologist at the institution’s Department of Earth Sciences named Simon Conway Morris declared that researchers can “say with reasonable confidence” that human-like evolution has occurred in other locations around the universe.

Using spacecraft and ground-based facilities, Russian astronomers have inspected the Orion Bar photodissociation region, focusing on the mid-infrared emission from this source. Results of the study could help astronomers to better understand the evolution of polycyclic aromatic hydrocarbons in space. The research was published November 10 on arXiv.org.

At a distance of about 1,300 away, the Orion Nebula is the nearest of massive star formation to Earth, with a complex and extensive gas structure. It hosts the so-called “Orion Bar”—a ridge-like feature of gas and dust formed by the intense radiation from nearby, hot, young stars, which appears to be shaped like a bar.

The Orion Bar is a photodissociation region or photon-dominated region (PDR). In general, PDRs are regions in the interstellar medium (ISM) at the interface between hot ionized gas and cool molecular gas that are energetically dominated by non-ionizing ultraviolet photons.

The bestselling author and historian offers his predictions on how technology will alter the evolution of humans and change society. Anderson Cooper reports.

“60 Minutes” is the most successful television broadcast in history. Offering hard-hitting investigative reports, interviews, feature segments and profiles of people in the news, the broadcast began in 1968 and is still a hit, over 50 seasons later, regularly making Nielsen’s Top 10.

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“De-Extinction” Biotechnology & Conservation Biology — Ben Novak, Lead Scientist Revive & Restore


Ben Novak is Lead Scientist, at Revive & Restore (https://reviverestore.org/), a California-based non-profit that works to bring biotechnology to conservation biology with the mission to enhance biodiversity through the genetic rescue of endangered and extinct animals (https://reviverestore.org/what-we-do/ted-talk/).

Ben collaboratively pioneers new tools for genetic rescue and de-extinction, helps shape the genetic rescue efforts of Revive & Restore, and leads its flagship project, The Great Passenger Pigeon Comeback, working with collaborators and partners to restore the ecology of the Passenger Pigeon to the eastern North American forests. Ben uses his training in ecology and ancient-DNA lab work to contribute, hands-on, to the sequencing of the extinct Passenger Pigeon genome and to study important aspects of its natural history (https://www.youtube.com/watch?v=pK2UlLsHkus&t=1s).