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I know so many people who will benefit from this.


During the 2014 FIFA World Cup opening ceremony, a young Brazilian man, paralyzed from the chest down, delivered the opening kickoff. He used a brain-machine interface, allowing him to control the movements of a lower-limb robotic exoskeleton.

This unprecedented scientific demonstration was the work of the Walk Again Project (WAP), a nonprofit, international research consortium that includes Alan Rudolph, vice president for research at Colorado State University, who is also an adjunct faculty member at Duke University’s Center for Neuroengineering.

Barely two years after the demonstration, the WAP has released its first clinical report, published Aug. 11 in Scientific Reports. They report that a group of patients who trained throughout 2014 with the WAP’s brain-controlled system, including a motorized exoskeleton, have regained the ability to voluntarily move their leg muscles and to feel touch and pain in their paralyzed limbs. This, despite being originally diagnosed as having a clinically complete spinal cord injury — in some cases more than a decade earlier.

Eight completely paralysed people have regained function in their limbs following virtual reality training, in an accidental result that has astonished even the scientists involved.

Using a brain-machine interface, scientists showed that people with long-term severe paralysis could retrain the few remaining connections in their damaged spines, letting their brains talk to their extremities once more. This enabled them to feel sensation, move their limbs and improved their bladder and bowel control.

The results came about as a wholly unexpected side effect of training to help people use robotic exoskeletons, which let them walk upright.

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In Greek mythology, the Chimera is a monster that is part lion, part goat and part snake. Far from reality, sure, but the idea of mixing and matching creatures is real — and has ethicists concerned.

That’s because last week, the National Institutes of Health proposed a new policy to allow funding for scientists who are creating chimeras — the non-mythological kind. In genetics, chimeras are organisms formed when human stem cells are combined with tissues of other animals, with the potential for creating human-animal hybrids.

Pablo Ross of the University of California, Davis, inserts human stem cells into a pig embryo as part of experiments to create chimeric embryos.

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The benefits of the technology for humans, while still largely hypothetical, are promising. The sensors could allow physicians to monitor the health of organs, create new therapies for neurological disorders, and help the physically impaired to control prosthetics.

While chips have been implanted in humans and other animals before, these sensors mark a significant improvement because they are small, wireless, batteryless, and could last in the body for years without degrading, said Michel Maharbiz, the associate professor who devised and studied the sensors alongside neuroscientist Jose Carmena.

“Hopefully the [tiny sensors] demonstrate a new direction for the field, and then you could build the consensus that’s needed to drive these forward,” Maharbiz said.

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It reminds of the medieval knight armor.


Power Armor. A powered exoskeleton with a tough outer shell, coupled with twice the mobility of a normal soldier and the strength of an elephant.

For decades, media has emulated what scientists have been struggling to create for millennia. Armor strong enough to both protect the wearer, and strengthen them through mechanical support.

In recent years, researchers have nearly achieved this kind of technology, with body armor reaching durability tougher than steel, and hobbyists making exoskeletons which can lift hundreds of pounds.

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