Lifeboat Foundation

To overcome that limitation, MIT researchers have developed a computational technique that allows large language models to predict antibody structures more accurately. Their work could enable researchers to sift through millions of possible antibodies to identify those that could be used to treat SARS-CoV-2 and other infectious diseases.

The findings are published in the journal Proceedings of the National Academy of Sciences.

Prof Zhang Zhiyong’s team at Peking University developed a heterojunction-gated field-effect transistor (HGFET) that achieves high sensitivity in short-wave infrared detection, with a recorded specific detectivity above 10¹⁴ Jones at 1,300 nm, making it capable of starlight detection. Their research was recently published in the journal Advanced Materials, titled “Opto-Electrical Decoupled Phototransistor for Starlight Detection.”

Highly sensitive shortwave infrared (SWIR) detectors are essential for detecting weak radiation (typically below 10⁻⁸ W·Sr⁻¹ ·cm⁻² ·µm⁻¹) with high-end passive image sensors. However, mainstream SWIR detection based on epitaxial photodiodes cannot effectively detect ultraweak infrared radiation due to the lack of inherent gain.

Filling this gap, researchers at the Peking University School of Electronics and collaborators have presented a heterojunction-gated field-effect transistor (HGFET) that achieves ultra-high photogain and exceptionally low noise in the short-wavelength infrared (SWIR) region, benefiting from a design that incorporates a comprehensive opto-electric decoupling mechanism.

Scientists at EPFL achieved a breakthrough by synchronizing six mechanical oscillators into a collective quantum state, enabling observations of unique phenomena like quantum sideband asymmetry. This advance paves the way for innovations in quantum computing and sensing.

Quantum technologies are revolutionizing our understanding of the universe, and one promising area involves macroscopic mechanical oscillators. These devices, already integral to quartz watches, mobile phones, and telecommunications lasers, could play a transformative role in the quantum realm. At the quantum scale, macroscopic oscillators have the potential to enable ultra-sensitive sensors and advanced components for quantum computing, unlocking groundbreaking innovations across multiple industries.

Achieving control over mechanical oscillators at the quantum level is a critical step toward realizing these future technologies. However, managing them collectively poses significant challenges, as it demands nearly identical units with exceptional precision.

Quantum walks, leveraging quantum phenomena such as superposition and entanglement, offer remarkable computational capabilities beyond classical methods.

These versatile models excel in diverse tasks, from database searches to simulating complex quantum systems. With implementations spanning analog and digital methods, they promise innovations in fields like quantum computing, simulation, and graph theory.

Harnessing Quantum Phenomena for Computation.

It’s time to stop doubting quantum information technology.

Are we there yet? No. Not by a long shot. But the progress on a number of key challenges, the sheer number of organizations fighting to succeed (and make a buck), the no-turning-back public investment, and nasty international rivalry are all good guarantors.

It feels like quantum computing is turning an important corner, maybe not the corner leading to the home stretch, but likely the corner beyond the turning back point. We now have quantum computers able to perform tasks beyond the reach of classical systems. Google’s latest break-through benchmark demonstrated that. These aren’t error corrected machines yet, but progress in error correction is one of 2024’s highlights.

The “expansion protocol” would be a lot more invasive than you’d enjoy.

Background and objectives: Aging clocks are computational models designed to measure biological age and aging rate based on age-related markers including epigenetic, proteomic, and immunomic changes, gut and skin microbiota, among others. In this narrative review, we aim to discuss the currently available aging clocks, ranging from epigenetic aging clocks to visual skin aging clocks.

Methods: We performed a literature search on PubMed/MEDLINE databases with keywords including: “aging clock,” “aging,” “biological age,” “chronological age,” “epigenetic,” “proteomic,” “microbiome,” “telomere,” “metabolic,” “inflammation,” “glycomic,” “lifestyle,” “nutrition,” “diet,” “exercise,” “psychosocial,” and “technology.”

Results: Notably, several CpG regions, plasma proteins, inflammatory and immune biomarkers, microbiome shifts, neuroimaging changes, and visual skin aging parameters demonstrated roles in aging and aging clock predictions. Further analysis on the most predictive CpGs and biomarkers is warranted. Limitations of aging clocks include technical noise which may be corrected with additional statistical techniques, and the diversity and applicability of samples utilized.

In a breakthrough set to revolutionize the semiconductor industry, the School of Engineering of the Hong Kong University of Science and Technology (HKUST) has developed the world’s first-of-its-kind deep-ultraviolet (UVC) microLED display array for lithography machines. This enhanced efficiency UVC microLED has showcased the viability of a lowered cost maskless photolithography through the provision of adequate light output power density, enabling exposure of photoresist films in a shorter time.

Conducted under the supervision of Prof. Kwok Hoi-Sing, Founding Director of the State Key Laboratory of Advanced Displays and Optoelectronics Technologies at HKUST, the study was a collaborative effort with the Southern University of Science and Technology, and the Suzhou Institute of Nanotechnology of the Chinese Academy of Sciences.

A lithography machine is crucial equipment for semiconductor manufacturing, applying short-wavelength ultraviolet light to make integrated circuit chips with various layouts. However, traditional mercury lamps and deep ultraviolet LED light sources have shortcomings such as large device size, low resolution, high energy consumption, low light efficiency, and insufficient optical power density.

Special multi-layer mirrors guide the light through plates called masks, which hold the intricate patterns of the integrated circuits for semiconductor wafers. The light projects the pattern onto a photoresist layer that is etched away to leave the integrated circuits on the chip, according to a press release by LLNL.

The project also aims to investigate the primary hypothesis that the energy efficiency of existing EUV lithography sources for semiconductor production can be improved with technology developed for the novel petawatt-class BAT laser, which uses thulium-doped yttrium lithium fluoride (Tm: YLF) as the gain medium through which the power and intensity of laser beams are increased, as per the release.

Scientists have planned to conduct a demonstration pairing the compact high-rep-rate BAT laser with technologies that generate sources of EUV light using shaped nanosecond pulses and high-energy x-rays and particles using ultrashort sub-picosecond pulses.