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Laura Trachsel-Moncho, Anne Simonsen and colleagues (Universitetet i Oslo (UiO)) identify the endosomal protein SNX10 as a modulator of piecemeal mitophagy of OXPHOS machinery components and mitochondrial homeostasis. They show that loss of SNX10 enhances mitochondrial protein degradation, reduces respiration, and increases ROS levels, leading to elevated cell death in vivo.


Trachsel-Moncho et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s.

Alzheimer’s disease is a progressive neurological disorder that primarily affects older adults, leading to memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia. The disease is characterized by the buildup of amyloid plaques and tau tangles in the brain, which disrupt cell function and communication. There is currently no cure, and treatments focus on managing symptoms and improving quality of life.

I predict most of humanity will be living in space habitats by the end of century and the beginning of the 22nd century O’Neil colonies and generation ships will be built out of hollowed out asteroids and it will be like james blish cities in space and George zebrowskis macrolife the colonizing of the galaxy.


Download : https://mega.nz/folder/IRoWHJ6K#8MecdlB3gMRMt3yKoSKFQQ

Video made with FL Studio ZGameEditor Visualizer plugin.

All the songs and samples used in the video belong to their respective owners and I don’t claim any right over them.

Centenarians, once considered rare, have become commonplace. Indeed, they are the fastest-growing demographic group of the world’s population, with numbers roughly doubling every ten years since the 1970s.

How long humans can live, and what determines a long and healthy life, have been of interest for as long as we know. Plato and Aristotle discussed and wrote about the ageing process over 2,300 years ago.

The pursuit of understanding the secrets behind exceptional longevity isn’t easy, however.

Rab5 is a cellular GTPase essential for endocytic clearance of invading pathogens. This study from Shino Tanaka, Hiromu Oide, Tomoko Kubori, Kohei Arasaki (Tokyo University of Pharmacy and Life Sciences) and colleagues reveals that the bacterial pathogen Legionella pneumophila ubiquitinates Rab5 to recruit a Rab5 inactivator RabGAP-5 to its phagosome, thereby excluding Rab5 and facilitating its intracellular replication.

Scientists Develop Hydrogel That Heals Wounds in Just 24 Hours! Researchers at UCLA have created a groundbreaking human skin-like hydrogel that repairs wounds 90% in just 12 hours and fully heals them within 24 hours! ✔This futuristic material mimics real skin, speeding up tissue regeneration like never before. While still in testing, this could revolutionize wound care, making slow healing a thing of the past. #wounds #superskin #skin #Health #healthylifestyle

Happy International Women’s Day to all the women around the world!

I had a great time interviewing Theodora Lau for the (A)bsolutely (I)ncredible podcast on Thursday, ahead of International Women’s Day.

S new book on Amazon: [ https://amzn.to/4iwVogr](https://amzn.to/4iwVogr) ‘ + s Day is this Saturday, and LinkedIn News is spotlighting conversations around today LinkedIn News asked me to share a short-form video about a lesson a woman mentor or colleague taught me and post it with the hashtag #IWD25

S Theodora with her perspective on representation in Artificial Intelligence and in financial services… + m still editing the full interview I will post some more shorts like this one from the interview today for International Women Join the conversation by sharing a short-form video about a lesson a woman mentor or colleague taught you that still shapes your career today using the hashtag #IWD25 to show your support for billions of women around the world.

D like to promote your (A)bsolutely (I)ncredible executive, brand, or product in an interview on the Neural News Network reach out to me directly.


There is no lack of hype around artificial intelligence. We have only begun to scratch the surface of what this powerful technology can do. While tech and financial services become more intertwined, cutting through the noise has become more difficult but also more crucial.

Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their healthy eyes.

The cornea is the outer layer of the eye, which focuses light towards the retina. Since it’s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth and functional.

Unfortunately, injuries like thermal or chemical burns can damage the cornea beyond the capability of these resident stem cells. There’s not much else that can be done – even a cornea transplant won’t take hold if the damage is too severe.

For our Medical Nanobots, in 5 to 10 years, once they are ready to go and wipe out all diseases.


Some bacteria deploy tiny spearguns to retaliate against rival attacks. Researchers at the University of Basel mimicked attacks by poking bacteria with an ultra-sharp tip. Using this approach, they have uncovered that bacteria assemble their nanoweapons in response to cell envelope damage and rapidly strike back with high precision.