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10 Bold Biotech Predictions That Will Shock You

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Artificial Wombs Are on the Verge of Human Trials. SEE to believe!

This week, The Circuit explores the cutting-edge technology of artificial wombs! Discover how engineers and scientists are working to save premature babies and even endangered species.
In this episode, we look at:

• The development of artificial womb technology for human preemie babies.
• How the Okinawa Churaumi Aquarium is using artificial wombs to save.
shark embryos.
• How bioengineers were able to grow a premature lamb in a biobag.

Artificial wombs represent a fascinating intersection of biology and engineering.

What are YOUR thoughts on the artificial womb? Amazing or frightening?

#ArtificialWomb #Preemies #SharkConservation #Biology #Engineering #NeonatalCare #MedTech #TheCircuit #Pregnancy #Doctors #Hospital #Healthcare

Could Light Therapy Be the Key to Easing Alzheimer’s Symptoms?

Light therapy is emerging as a promising, non-pharmacological treatment for Alzheimer’s.

Alzheimer’s disease is a progressive neurological disorder that primarily affects older adults, leading to memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia. The disease is characterized by the buildup of amyloid plaques and tau tangles in the brain, which disrupt cell function and communication. There is currently no cure, and treatments focus on managing symptoms and improving quality of life.

Turning Off Anxiety: Scientists Discover the Brain’s Hidden Switch

Using light-sensitive drugs, they identified a promising neural pathway that could lead to more effective, safer anxiety treatments.

Targeting Anxiety with Brain Circuit Research

Researchers at Weill Cornell Medicine have identified a specific brain circuit that, when inhibited, reduces anxiety without causing noticeable side effects — at least in preclinical models. Their findings highlight a potential new target for treating anxiety disorders and introduce a broader strategy for studying drug effects in the brain using a technique called photopharmacology.

Scientists discover new type of life form living in the human body

CINCINNATI (WKRC) — Researchers believe they discovered a new type of life form living in the human body that were previously misidentified as viruses.

According to a new study from bioRxiv that has yet to be peer reviewed, researchers identified a new type of life form in the human body, which they called “Obelisks,” that appeared similar to viruses but with multiple key differences that make them a different type of organism.

For starters, the Obelisks do not match any previously recognized virus, so if they are viruses they are brand new. The researchers said that it’s highly unlikely the Obelisks are viruses, since they identified over 30,000 different variants, and they would have expected to find a match for a previously identified virus among so many variations.

Complex Selective Manipulations of Thermomagnetic Programmable Matter | Paper

Link to paper: 10.1038/s41598-022–24543-5

Programmable matter can change its shape, stiffness or other physical properties upon command. Previous work has shown contactless optically controlled matter or magnetic actuation, but the former is limited in strength and the latter in spatial resolution. Here, we show an unprecedented level of control combining light patterns and magnetic fields. A mixture of thermoplastic and ferromagnetic powder is heated up at specific locations that become malleable and are attracted by magnetic fields. These heated areas solidify on cool down, and the process can be repeated. We show complex control of 3D slabs, 2D sheets, and 1D filaments with applications in tactile displays and object manipulation. Due to the low transition temperature and the possibility of using microwave heating, the compound can be manipulated in air, water, or inside biological tissue having the potential to revolutionize biomedical devices, robotics or display technologies.

LinkedIn: Reflections of Professor Bernard J Baars Professor Baars is a former Senior Fellow in Theoretical Neurobiology at the Neurosciences Institute in San Diego where he is currently an Affiliated Fellow

He has written five well received books on consciousness and developed the Global Neural Workspace model of Consciousness What follows bellow are some of Professor Baars’ observations, Questions (often rhetorical), Quotations, comments, reflections on career and his own theories and my comments (RS) to them as posted to LinkedIn platform. Bernard’s text is in italics. Comments to comments are indicated with ‘BB]’ and responses to those with ‘RS]’. ======== ======== ======== t aware of. ‘ +In the case of non-human animals, we have to get a little bit more creative. We have to decide what behaviors can be used similar sorts of markers as their own form of report.” — David Edelman RS] Or we could ask ~ “is the form of communication between animals sufficient for their needs?” and follow up with “is there Evolutionary Pressure for forms of communication beyond utility?” Those who follow discussion forums may appreciate that what takes an excited discussant 10 paragraphs and 1,000 flaming words can be achieved by a dog with a couple barks and the bearing of teeth ~ which is the more efficient communicative format? BB] Humans seem to have a larger repertoire of uses for consciousness — including language and longer-term planning, self-monitoring and self-reflection, inner speech, metaphor, symbolic representation of experience and deliberate use of imagery. When it comes to sensory consciousness, however, the brain shows little difference between humans and many other mammals. RS] Utility is the key ~ what are those faculties good for? Take them away, individually, and see what we end up with. As such surgical or other intervention is not a practical option we might turn to clinical conditions where patients have such deficits. We may look to Autism, where self reflection, especially in the social context, is lacking. Psychopathy, where there is no inner voice reflecting on social morals. Various other deficits leave individuals with greatly reduced capacity to strive in a community and so we may reflect on the many cognitive faculties we have that appear to have little if any use for the isolated individual. To test this we may examine those who were completely isolated for a significant period of their maturation. There have been cases of children lost in the forest (or dumped there) who survived. Without social stimulation some of heir faculties never matured ~ are these the same faculties that Bernard mentions above? BB] Perhaps half a second after you glance at a word on a page it is converted into a semantic code, to interpret its meaning, guided by the rules of grammar. Going from words to meaning requires a large, unconscious mental lexicon. The lexicon of educated speakers of English contains about 100,000 words. We can understand each one instantly, as soon as it is shown in a sentence that makes sense. Words are complicated things! The OxfordEnglish Dictionary, for example, devotes 75,000 words to clarifying the many different meanings of the word set. RS] The way words are interpreted gives us insight into the how the brain works. If approached in the follow manner we can see what is happening: For each noun there is a denotation and a connotation (the cold dictionary definition and the feeling the word evokes eg ‘Home’). There is a stand alone and contextual meaning of a word that may differ significantly eg “child” and “What are parent-child tree structures in SQL?” The ‘connotation’ is used by the brain to link words into sentences more so than the denotation. If there is a universal background language in the brain, then, it would be based on connotation, not denotation. Why? Because the connotation is innate already and words are appended to pre-existing ‘connotation’ made up of emotion, drives, feelings of all kinds. Watch a child as they acquire their first words ~ they at first use all kinds of signals to convey their intent, their intent is made up of drives, cravings, feelings etc and these become the connotations behind the words they eventually use. s BB] How does the metaphor of a theater help us think about consciousness? RS] The key to many of these approaches, and possible the downfall of at least some of them, is ‘evolvability’. We assume, from our own intuitive experience and logical deduction, that there must be a primary central control. This is a ‘top-down’ approach. But evolution must, by necessity, be ‘bottom-up’. Thus we would expect even the simplest ganglion to have at least some of the properties of consciousness in its own right. Snakes that must rely on different ‘consciousnesses’ for various functions, for instance the pursuing of prey, the killing of prey and the eating of the prey all come from processes so separate that if a mouse after a poisonous bite staggers around and ends up under the snake’s nose the snake will follow the scent trail until it ends up at the mouse, the visual and feeding systems not being able to share information. That system is evolvable, the top-down, apart from religious models, is not evolvable. Thus instead of a separate central process looking down at the senses we consider how the senses and other contributors to cognition swirl together like the funnel of a tornado to form a central consciousness that, in reality, has no independent neural underpinnings of its own due to its emergent nature. Note that ‘life’ also has this nature in that life exists when a collection of chemical reactions ‘swirl’ together, principally in a negative feedback driven homeostatic process, which is most probably also what consciousness actually is… And so we observe how the tornado’s funnel moves around the possible contributors, the audience in the analogy given, rather than a separate process that looks at individual members of the audience. Note that the separate process must consume the information on offer and process it, a ‘infinite regress’ with no end. But the swirling tornado, so to speak, is its own end and does not require any subsequent processes or processing… Note also that any collection of neurons, brain modules or even collections or communities of people can initiate this process.


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