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Researchers have demonstrated that telomerase gene therapy does not increase the risk of cancer, even in strains of mice that are particularly susceptible to cancer [1].

A tale of telomeres

Short telomeres trigger cellular senescence and are thought to be one of the primary hallmarks of aging, which has led to various researchers seeking ways to restore the telomeres in order to prevent cells from dying and to encourage division and tissue regeneration. We won’t go over the basics of telomeres and how they influence aging here, but if you would like to learn more, check out our telomeres article, which explains it all.

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Sugar may be the villain of our time, with too much of the sweet stuff known to be a leading cause of developing diabetes. But now researchers at Washington University School of Medicine in St. Louis have discovered a new way to reduce the risk of this condition – sugar. Trehalose is a natural sugar that has now been found to deprive the liver of glucose and activate a gene that improves insulin sensitivity and triggers the burning of more fat.

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“The big problem is that hospitals don’t buy new devices, and they keep using really dangerous ones ad infinitum — until they just stop working,” Corman said.

Corman wants these old, unsecured devices gone from hospitals. The fear is that, beyond freezing systems or hijacking medical records as they did during WannaCry, hackers could also actively manipulate medical equipment to harm patients by, say, administering a lethal dose of medication via an infusion pump. While newer devices aren’t ironclad, they are typically built with more robust security features. So Corman and others are urging health-care providers to scrap old, or “legacy,” equipment and replace it with newer models.

To nudge health-care providers to trade up, he’s put forth an idea for an incentive program akin to “Cash for Clunkers,” the 2009 federal auto-rebate plan that aimed to run gas-guzzling cars off the road. Under that program, which was formally called the Car Allowance Rebate System, people received cash in exchange for turning in fuel-inefficient vehicles, which they could then put toward new, more efficient ones. (The program fizzled after a few months, when it depleted its allotted budget.) Similarly, in this version, health-care providers would be compensated for junking old equipment, and could use the rebates toward the purchase of new devices. Corman said he hasn’t fully worked out the economics, but he believes device makers might be willing to subsidize the program in part, since it would help them move inventory.

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Our ultimate mission is to make 100 years old the new 60.”


A new exploration of stem cells from placentas could drastically advance regenerative medicine. Peter Diamandis, X-Prize and Singularity University founder, recently teamed up with Robert Hariri, the founder of Celgene Cellular Therapeutics, to study these specific stem cells in the hopes of discovering new regenerative therapies.

The initiative, called Celularity, is built around the idea that stem cells found in the human placenta (which transports nutrients to fetuses as they grow) are ideal for regenerating tissue and organs. According to Celularity, the cells can be taken from any placenta, which typically just gets discarded, and placed into any human without the risk of rejection.

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On an early spring morning, a humming drone hovered over a small town in Bahia, Brazil. Three hundred feet above ground, a small canister clicked open, ejecting its contents into the mouth of the release mechanism below. For a moment, there was silence. Then, a swarm of mosquitoes, freshly awoken from icy slumber, stretched their wings and took flight.

Each specimen was male, single and ready to mingle—and if all went as planned, the buzzing horde of eager virgins would steadily infiltrate the local mosquito population, coupling up with thousands of lucky ladies in the days to come.

Considering that there are about 100 species of mosquito that carrying deadly human pathogens—including parasites that cause malaria, as well as Zika, dengue and West Nile viruses—this may sound like the horrifying start to an apocalyptic science fiction film à la Outbreak. But it’s quite the opposite: The mosquitoes unleashed in this experiment may be some of the best weapons against the spread of infectious disease.

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