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Category: biotech/medical – Page 2393

Ichor Therapeutics, a life science company in Lafayette, New York, is one of the big players in the world of rejuvenation biotechnologies. Since its founding in 2013, it has been growing and expanding its portfolio of companies working on therapies against the diseases of aging; on August 1, 2018, Ichor announced the formation of its strategic fund, Grapeseed.bio.

What is Grapeseed.bio

This new fund and accelerator program is meant to provide young life science startups with seed funding up to $100,000, technical training, mentorship, and full access to Ichor’s large research laboratory.

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The United States is still the preeminent location for scientific research, but this is not a given, and we should not take it for granted. The new policies being implemented by China, and especially their ambition to attract outside talent, could quickly drain the lifeblood of our scientific institutions. Without a determined effort to attract, support, and retain leading researchers, we cannot expect to drive the breakthroughs, technologies, and medicines of the future. Massachusetts has admirably made a strong commitment to biotechnology through the Life Sciences Initiative. But will this be enough to sustain the scientific ecosystem of the entire country?

The United States is in danger of losing its primacy in scientific research.

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The July edition of the Journal Club has us taking a look at a recent paper that casts doubt and concern over the use of CRISPR Cas9 for gene editing.

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The paper we are discussing can be found here: https://www.nature.com/articles/nbt.

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For centuries humans have sought the ‘elixir of life’ – a mythical potion that supposedly would grant the drinker eternal life.

Now Exeter scientists believe they may have found the secret to a longer, healthier life.

New compounds developed and tested at the University of Exeter have brought the dream a step closer and paved the way for “anti-degeneration” drugs that could not only extend life, but also extend health and may help treat age-related diseases like cancer, dementia and diabetes.

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The compounds — AP39, AP123 and RT01 — have been designed to selectively deliver minute quantities of the gas hydrogen sulphide to the mitochondria in cells and help the old or damaged cells to generate the ‘energy’ needed for survival and to reduce senescence.

In the samples used, the number of senescent cells — older cells that have deteriorated and stopped dividing — was reduced by up to 50 per cent.

The team also identified two splicing factors — a component of cells — that play a key role in when and how endothelial cells become senescent.

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