Can cutting-edge new treatments and therapies put an end to cardiovascular and circulatory disease for good?
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Category: biotech/medical – Page 2250
WASHINGTON — A new study offers some of the strongest evidence yet of the connection between the marketing of opioids to doctors and the nation’s addiction epidemic.
It found that counties where opioid manufacturers offered a large number of gifts and payments to doctors had more overdose deaths involving the drugs than counties where direct-to-physician marketing was less aggressive.
The study, published Friday in JAMA Network Open, said the industry spent about $40 million promoting opioid medications to nearly 68,000 doctors from 2013 through 2015, including by paying for meals, trips and consulting fees. And it found that for every three additional payments that companies made to doctors per 100,000 people in a county, overdose deaths involving prescription opioids there a year later were 18 percent higher.
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A broader range of treatments for this disorder offers patients a more personalized approach.
- By David Blum on January 18, 2019
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A vocal minority in the United States is intent on stopping federal funding for research using human fetal tissue, citing stem cell–based or other alternatives as adequate. This view is scientifically inaccurate. It ignores the current limitations of stem cell research and disregards the value of fetal tissue research in finding therapies for incurable diseases. If there is to be continued rapid progress in treating cancer, birth defects, heart disease, and infectious diseases, then we need fetal tissue research.
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Ultrasound technology has been in wide use for decades, helping submarines navigate and letting doctors non-invasively peer inside patients, but it might be about to get a whole lot more powerful. Researchers have developed an “ultra” ultrasound sensor that is so sensitive it can hear air molecules moving around or the vibrations of individual cells.
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Age-related macular degeneration is the leading cause of vision loss in seniors, and existing treatments are few.
But now, experiments in pigs and rats suggest that stem cell therapy might help curb at least one form of the disease.
The results could soon lead to the first human trials of this therapy for macular degeneration, according to researchers from the U.S. National Eye Institute (NEI).
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“We wanted to be more precise here and identify the region and the cells that are responsible for pain unpleasantness,” Scherrer tells Inverse. “We thought if we could find the center, or the cells in the brain that make pain unpleasant, perhaps acting on these cells could be a good strategy to reduce pain in chronic pain patients.”
It’s already established that the amygdala plays a role in the emotional component of pain, but this team actually found the exact cells in the amygdala responsible for those unpleasant pain messages by using a “miniscope,” a tool created by Schnitzer, and observing how mice responded to painful stimuli.
When mice in their experiment were exposed to a drop of scalding water, a given a pinprick, or asked to run along unpleasantly hot tracks, these cells in the amygdala were highly active. Importantly, Schnitzer adds, they didn’t light up when the mice were exposed to other stimuli like sugar water or a bad smell. “Every time mice were unpleased with the stimulation, we saw that these cells were turned on,” he adds.
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