Lifeboat Foundation

The method has been trialled successfully, and could be ready for use in as little as four years.

Metabesity 2019: Epigenetic resetting of cellular age mediated by nuclear reprogramming – A new paradigm in overcoming aging and aging-associated diseases.
Featuring Vittorio Sebastiano, PhD, Assistant Professor of Stanford University; Co-Founder of Turn Biotechnologies, USA

For more information, see www.metabesity2019.com

On a farm in Bavaria, German researchers are using gene editing to create pigs that could provide organs to save thousands of lives.

Very interesting.

Numerous vaccines, from flu shots to those those that help thwart chickenpox and measles, are widely used to guard against contagion, but researchers in France are proposing a breakthrough role for rotavirus vaccines: deploying them in cancer treatment.

Scientists from throughout France—Paris, Lyon, Villejuif and beyond—are part of a large research team that has asked a tantalizing question: Can rotavirus vaccines be repurposed to overcome resistance in cancer immunotherapy? The team is focusing on resistance that emerges to the form of cancer treatment known as checkpoint blockade immunotherapy.

Continue reading “Rotavirus vaccine: A potential new role as an anticancer agent” »

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the ‘runaway train’ that is Parkinson’s disease.

The team, based at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) in the School of Life Sciences, have discovered a new enzyme that inhibits the LRRK2 pathway. Mutations of the LRRK2 gene are the most common cause of genetic Parkinson’s.

Enzymes are molecular machines that regulate the biological processes required to maintain healthy functioning life. They can also be targeted by drugs to increase or decrease the level of certain activity –in this instance the LRRK2 pathway.

A Portland teen won second place in a national technology contest, taking home $2,500 that he can use to attend science camp next summer.

Rishab Jain, 14, is a freshman at Westview High School. His winning project, which he calls the Pancreas Detective, is an artificial intelligence tool that can help diagnose pancreatic cancer through gene sequencing. The algorithm helps doctors focus on the organ during examinations, which is often obscured because it moves around the abdominal area as patients breathe and other bodily functions shift other organs as well.

Last year, the same project netted $25,000 from 3M when he attended Stoller Middle School. He used that money to fund his nonprofit, Samyak Science Society, which promotes science, technology, engineering and math education for other children, Time Magazine reported.

Unlike chemotherapy or radiation, which attack cancer directly, CAR-T engineers patients’ immune cells so they can do it themselves. T-cells are removed from the blood and given new genes that produce receptors that let the T-cells recognize and bind to leukemia cells with a specific protein, CD19.

The genetically modified T-cells are then multiplied in the lab and infused back into the patient, where they ideally multiply even further and begin to target and kill cancer cells with CD19.

Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.

“Right now, whatever is available as a clinical product is more like a fancy Band-Aid,” said Pankaj Karande, an associate professor of chemical and biological engineering and member of the Center for Biotechnology and Interdisciplinary Studies (CBIS), who led this research at Rensselaer. “It provides some accelerated wound healing, but eventually it just falls off; it never really integrates with the host cells.”

Continue reading “Living skin can now be 3D-printed with blood vessels included” »

https://youtube.com/watch?v=jtNsxqG4AfQ

Oct. 29 is World Stroke Day. Sometimes called a brain attack, stroke is the second leading cause of death worldwide and the fifth leading cause of death in the U.S. Men and women are at risk of a stroke, but women are more likely to have – and die – of a stroke than men. Dr. Kara Sands, a Mayo Clinic neurologist, says stroke kills twice as many women as breast cancer. The good news is that strokes are preventable, treatable and beatable.

Watch: The Mayo Clinic Minute

Continue reading “Mayo Clinic Minute: What you need to know about stroke” »