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Category: biotech/medical – Page 1,864

Resveratrol may reduce aging within the brain.

Deficits in the cerebral microcirculation contribute to age-related cognitive decline. In a pilot study of postmenopausal women, we found that supplementation with a low dose of resveratrol, a phytoestrogen, for 14 weeks improved cerebrovascular and cognitive functions. We have since undertaken a larger, longer term study to confirm these benefits. Postmenopausal women aged 45–85 years (n = 129) were randomized to take placebo or 75 mg trans-resveratrol twice daily for 12 months. Effects on cognition, cerebral blood flow, cerebrovascular responsiveness (CVR) and cardiometabolic markers (blood pressure, diabetes markers and fasting lipids) were assessed. Compared to placebo, resveratrol improved overall cognitive performance (P < 0.001) and attenuated the decline in CVR to cognitive stimuli (P = The latter effect was associated with reduction of fasting blood glucose (r = P = This long-term study confirms that regular consumption of resveratrol can enhance cognitive and cerebrovascular functions in postmenopausal women, with the potential to slow cognitive decline due to ageing and menopause. View Full-Text.

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Researchers at the University of Central Florida (UCF) are working to create a protective coating that would include a new nanomaterial to catch #COVID19 and kill it within seconds.

ORLANDO, Fla., April 10, 2020 — The masks that health care workers wear to protect them from the virus that causes COVID-19 block the virus before it reaches their faces, but do not destroy it. To further protect doctors, nurses, and others on the front lines of the pandemic, researchers at the University of Central Florida (UCF) are working to create a protective coating that would include a new nanomaterial to catch the virus and kill it within seconds.

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If you’ve been interested in nanotech, but have been too afraid to ask, here is an introductory and interesting article that I’d like to recommend.

My interest in nanotech is based on my hope that nanotech can lead to methods of constructing substrates that are suitable for mind uploading. It may lead to a technique to create duplicate minds.

“These ‘biological engineering’ technologies have made real one of the dreams of the nanotechnology pioneers: the deployment of molecular assemblers able to construct any shape with atomic precision, following a rational design.”

“…hybrid bioinorganic devices that mimic biological processes will soon be used in new computers and electronic devices.”

In the mid-1980s, evidence started to emerge from labs across the world confirming that scientists were finally able to reach the nano level in experimental conditions and not just with their theories. Working at scales defined in millionths of a millimetre, Richard Smalley, Robert Curl and Harold Kroto reported the discovery of ‘buckminsterfullerene’ – a nanosized polyhedron, with 32 faces fused into a cage-like, soccer-ball structure, and with carbon atoms sitting in each of its 60 vertices.

These miniature ‘Bucky’ balls (named for their similarity to the geodesic dome structures made by the architect R Buckminster Fuller in the 1950s), are found in tiny quantities in soot, in interstellar space and in the atmospheres of carbon-rich red giant stars, but Kroto was able to recreate them in chemical reactions in the lab while visiting Rice University in Texas. Then, in 1991, Nadrian Seeman’s lab at New York University used 10 artificial strands of DNA to create the first human-made nanostructure, connecting up the DNA strands to resemble the edges of a cube, so marking the beginning of the field now known as ‘DNA nanotechnology’. Clever scientists with broad visions started to realise that a new kind of technology, prophesied by Richard Feynman in the 1950s, was finally materialising, as researchers achieved the capacity to visualise, fabricate and manipulate matter at the nanometre scale.

Continue reading “The future is nano, and it will revolutionise medical science Essays” | >

Ongoing clinical trial to test the effectiveness of vitamin C infusion to help fight against Covid-19:

2019 new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency. There is a lack of effective targeted antiviral drugs, and symptomatic supportive treatment is still the current main treatment for SARI.

Vitamin C is significant to human body and plays a role in reducing inflammatory response and preventing common cold. In addtion, a few studies have shown that vitamin C deficiency is related to the increased risk and severity of influenza infections.

We hypothize that Vitamin C infusion can help improve the prognosis of patients with SARI. Therefore, it is necessary to study the clinical efficacy and safety of vitamin C for the clinical management of SARI through randomized controlled trials during the current epidemic of SARI.

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The COVID-19 pandemic has put an incredible strain on global supply chains, from medical supplies to household goods, as spikes in demand stress-test logistics infrastructures. There is an opportunity for unmanned delivery vehicles to assist in addressing this demand and help to reduce the risk of spreading infection.

Here’s a look at some of the challenges and opportunities for automated vehicles (AVs) in last-mile deliveries and local logistics.

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Researchers from Kumamoto University have found that Melinjo seed extracts may help to improve diabetes and obesity by stimulating the production of adiponectin which is a hormone that works to help improve both conditions; individual genotype differences were also discovered that were responsible for variations in its efficacy.

Melinjo fruit contain high levels of antioxidant and antibacterial properties as well as high levels of polyphenols such as resveratrol that has been shown to induce adiponectin and may help to improve lifestyle related diseases such as metabolic syndrome. A type of resveratrol called Gnetin C which is found in MSE has higher antioxidant activity and has been shown to stay in the blood longer than resveratrol, but the exact mechanisms of how they exert their biological activity remains unknown.

Genetic analysis was used to find that differences in the type of DsbA-L gene affects adiponectin activation; meaning that DsbA-L induction may promote adiponectin activation and help to improve lifestyle related diseases. Their recent research has attempted to determine whether MSE enhances the function of DsbA-L; whether MSE promotes adi[onectin activation; and whether MSE has a therapeutic effect on either obesity and diabetes.

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Los vigilantes del parque Xixi Wetland de Hangzhou (China) emplean gafas de realidad aumentada que les permiten detectar qué personas tienen fiebre desde una distancia segura para minimizar los contagios de covid-19.

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Continue reading “Vigilantes de parque usan gafas de realidad aumentada para detectar a personas con fiebre en China” | >

What is a safe distance when running, biking and walking during COVID-19 times? It is further than the typical 1–2 meter as prescribed in different countries!

In a lot of countries walking, biking and jogging are welcome activities in these times of COVID-19. However, it is important to note that you need to avoid each other’s slipstream when doing these activities. This comes out of the result of a study by the KU Leuven (Belgium) and TU Eindhoven (Netherlands).

The typical social distancing rule which many countries apply between 1–2 meters seems effective when you are standing still inside or even outside with low wind. But when you go for a walk, run or bike ride you better be more careful. When someone during a run breathes, sneezes or coughs, those particles stay behind in the air. The person running behind you in the so-called slip-stream goes through this cloud of droplets.

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