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Category: biotech/medical – Page 1,484

The “Unknome”: A Database of Human Genes We Know Almost Nothing About

UK researchers have developed a new publicly accessible database, and they hope to see it shrink over time. That’s because it is a compendium of the thousands of understudied proteins encoded by genes in the human genome, whose existence is known but whose functions are mostly not.

The database, dubbed the “unknome,” is the work of Matthew Freeman of the Dunn School of Pathology, University of Oxford.

The University of Oxford is a collegiate research university in Oxford, England that is made up of 39 constituent colleges, and a range of academic departments, which are organized into four divisions. It was established circa 1096, making it the oldest university in the English-speaking world and the world’s second-oldest university in continuous operation after the University of Bologna.

Researchers develop plasmonic nanotweezers to more rapidly trap potentially cancerous nanosized particles

Vanderbilt researchers have developed a way to more quickly and precisely trap nanoscale objects such as potentially cancerous extracellular vesicles using cutting-edge plasmonic nanotweezers.

The practice by Justus Ndukaife, assistant professor of electrical engineering, and Chuchuan Hong, a recently graduated Ph.D. student from the Ndukaife Research Group, and currently a postdoctoral research fellow at Northwestern University, has been published in Nature Communications.

Optical tweezers, as acknowledged with a 2018 Physics Nobel Prize, have proven adept at manipulating micron-scale matter like biological cells. But their effectiveness wanes when dealing with nanoscale objects. This limitation arises from the diffraction limit of light that precludes focusing of light to the nanoscale.

Researchers develop a novel method to generate deep-UV light

This device can generate deep-UV light with a very narrow wavelength range that is safe for humans but lethal for germs.

A new device that can generate deep-ultraviolet (UV) light to kill germs without harming humans has been developed by a team of researchers from Osaka University, Japan. The device uses a novel method of combining two visible photons into one deep-UV photon inside a thin waveguide made of aluminum nitride, a material that has nonlinear optical properties.

The research, named “229 nm far-ultraviolet second harmonic generation in a vertical polarity inverted AlN bilayer channel waveguide,” has been published in the journal Applied Physics Express.

Have A Heart! We All Do, Actually…And AI Might Improve Cardio Care

Back to AI in healthcare – we’ve looked at this from a number of angles, but what about some of the pros and cons of using AI/ML systems in a clinical context? And also, what about how to conquer disease with AI models?

There’s a broader theory that AI is going to allow for trail-blazing research on everything from cancer and heart disease to trauma and bone and muscle health — and everything in between. Now, we have more defined solutions coming to the table, and they’re well worth looking at!

In this IIA talk, cardiologist Collin Stultz talks about the treatment of disorders, and new tools, starting with a dramatic emphasis on heart disease.

First robotic liver transplant in U.S. performed by Washington University surgeons

A surgical team from Washington University School of Medicine in St. Louis recently performed the first robotic liver transplant in the U.S. The successful transplant, accomplished in May at Barnes-Jewish Hospital, extends to liver transplants the advantages of minimally invasive robotic surgery: a smaller incision resulting in less pain and faster recoveries, plus the precision needed to perform one of the most challenging abdominal procedures.

The patient, a man in his 60s who needed a transplant because of liver cancer and cirrhosis caused by hepatitis C virus, is doing well and has resumed normal, daily activities. Typically, liver transplant recipients require at least six weeks before they can walk without any discomfort. The patient was walking easily six weeks after surgery and cleared to resume golfing and swimming seven weeks after the surgery.

Groundbreaking surgery performed at Barnes-Jewish Hospital in St. Louis.

New nanotech weapon takes aim at hard-to-treat breast cancer

Breast cancer in its various forms affects more than 250,000 Americans a year. One particularly aggressive and hard-to-treat type is triple-negative breast cancer (TNBC), which lacks specific receptors targeted by existing treatments. The rapid growth and metastasis of this cancer also make it challenging to manage, leading to limited therapy options and an often poor prognosis for patients.

A promising new approach that uses minuscule tubes to deliver cancer-fighting drugs directly to the tumor site while preserving has been developed by Johns Hopkins engineers. The team’s research appeared in Nanoscale.

“In this paper, we showed that we can use to specifically target both proliferating and senescent TNBC cells with chemotherapeutics and senolytics, killing them without targeting healthy breast cells,” said Efie Kokkoli, professor of chemical and biomolecular engineering, a core researcher at the Johns Hopkins Institute for NanoBioTechnology, and a specialist in engineering targeted nanoparticles for the delivery of cancer therapeutics.

DNA Breakthrough — How Genetic Shedding Unveils Species Secrets

Ecologists have shown that the genetic material that species.

A species is a group of living organisms that share a set of common characteristics and are able to breed and produce fertile offspring. The concept of a species is important in biology as it is used to classify and organize the diversity of life. There are different ways to define a species, but the most widely accepted one is the biological species concept, which defines a species as a group of organisms that can interbreed and produce viable offspring in nature. This definition is widely used in evolutionary biology and ecology to identify and classify living organisms.

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