A four-year study will help develop AI software that will speed up the process of matching donated kidneys with patients in need, especially those not at the top of the transplant list.
Category: biotech/medical – Page 1,483
Sepsis is one of the most expensive medical conditions in the world: Research clarifies how it can lead to cell death
Sepsis is a life-threatening condition arising from the body’s overreactive response against an infection, leading it to injure its own tissues and organs. The first known reference to “sepsis” dates back more than 2,700 years, when the Greek poet Homer used it as a derivative of the word “sepo,” meaning “I rot.”
Despite dramatic improvements in understanding the immunological mechanisms behind sepsis, it still remains a major medical concern, affecting 750,000 people in the U.S. and nearly 50 million people globally each year. Sepsis accounted for 11 million deaths worldwide in 2017, and is the most expensive medical condition in the U.S., costing over tens of billions of dollars annually.
We are researchers who study how certain types of bacteria interact with cells during infections. We wanted to understand exactly how an overreactive immune response can result in detrimental and even lethal effects like sepsis. In our research, newly published in Science Immunology, we discovered the cells and molecules that potentially trigger death from sepsis.
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I missed his interview six times over the past year. Dr. Ian Hale of London who has done research a epidemics of the past 2,500 years agreed to give his interview for the seventh time and this time it happened.
The summary which I outlined from our discussion is
1-Any epidemic has a minimum four years cycle and its true about CORONA too.
2–2023 will be a catastrophic year due to the spread of mutants first in Northern Hemisphere and then in the Southern.
3-The world needs to act together to save generations whether it’s creating hospitals, vaccines, masks, or creating awareness.
4-CORONA will stay for all time. For the first few years catastrophically and then in its mild form.
5-We need to get vaccinated, wear masks, avoid public gatherings and follow all precautions.
6-Situation will be worsening in 2023 across the world due to the spread of mutants.
7-Vaccines may not work on These mutants.
A new way of killing cancer cells could pave the way for a cure, scientists say
This was the first time scientists were able to develop a hairpin-shaped DNA strand that can activate a natural immune response to target and kill specific cancerous cells. Tuesday 27 December 2022 10:48 A new way of using DNA to kill cancer cells which could pave the way for a cure for the disease has been created by scientists.
Experts Debate the Risks of Made-to-Order DNA
In November 2016, virologist David Evans traveled to Geneva for a meeting of a World Health Organization committee on smallpox research. The deadly virus had been declared eradicated 36 years earlier; the only known live samples of smallpox were in the custody of the United States and Russian governments.
Evans, though, had a striking announcement: Months before the meeting, he and a colleague had created a close relative of smallpox virus, effectively from scratch, at their laboratory in Canada. In a subsequent report, the WHO wrote that the team’s method “did not require exceptional biochemical knowledge or skills, significant funds, or significant time.”
Evans disagrees with that characterization: The process “takes a tremendous amount of technical skill,” he told Undark. But certain technologies did make the experiment easier. In particular, Evans and his colleague were able to simply order long stretches of the virus’s DNA in the mail, from GeneArt, a subsidiary of Thermo Fisher Scientific.
Interviews of 2022: the longevity visionaries
Five of our favourite interviews with thought leaders and investors on the opportunity presented by longevity.
From spending billions on research to calls for fundamental changes to way we deliver healthcare, this year we heard from a host of thought leaders who shared their views on how to make longevity a reality. Today we bring you five of the best.
When we spoke to Professor Sir John Bell, we expected to learn more about a new UK initiative to study of the health of five million citizens to enable more effective ways to prevent, detect and treat diseases. But what we got was a stirring call to action for a change in the way healthcare is conducted.
Precision cardiovascular medicine prevents the development of heart diseases
Blood pressure genetic risk score can predict risk of heart attacks and stroke.
Nearly half of all American adults have elevated blood pressure or hypertension and high blood pressure contributes to 65 percent of cardiovascular deaths in the US. Now researchers at University of Alabama at Birmingham have used genomic information to create a blood pressure “genetic risk score”.
Longevity. Technology: Cardiovascular disease is the leading cause of death worldwide and is responsible for a significant burden of morbidity and mortality. As people age, their risk of developing CVD increases, making it a major contributor to the morbidity and mortality associated with aging. That there is a pressing need for research into CVD in order to identify effective strategies for prevention and treatment would seem obvious, but this research is particularly important as the global population is aging and the prevalence of CVD is expected to rise with it. However, having such an enormous number of people at risk brings extra problems – how can risks be quantified and determined on an individual basis? The answer could lie in understanding and leveraging genetic data.
Will Glycine Supplementation Reduce Homocysteine?
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New Research: This Activity Can Reduce the Risk of Metastatic Cancer
Professor Carmit Levy. Credit: Tel Aviv University.
Professor Carmit Levy from the Department of Human Genetics and Biochemistry and Dr. Yftach Gepner from the School of Public Health and the Sylvan Adams Sports Institute at TAU’s Sackler Faculty of Medicine conducted the study. Prof. Levy notes that the new research has resulted in a very important discovery by merging scientific know-how from different schools at TAU, which may help avoid metastatic cancer, Israel’s top cause of death. The study was recently published on the cover of the journal of Cancer Research.
Prof. Levy and Dr. Gepner: “Studies have demonstrated that physical exercise reduces the risk for some types of cancer by up to 35%. This positive effect is similar to the impact of exercise on other conditions, such as heart disease and diabetes. In this study we added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been ‘be active, be healthy’, now we can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer.”