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Jun 12, 2022

Scientists Discover New Molecule That Kills Hard-to-Treat Cancers

Posted by in categories: biotech/medical, mathematics

A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.

A study describing the research — which was carried out in isolated cells, in human cancer tissue and in human cancers grown in mice — was published online June 2 in the journal Nature Cancer.

Dr. Jung-Mo Ahn, a co-corresponding author of the study and a UT Dallas associate professor of chemistry and biochemistry in the School of Natural Sciences and Mathematics, has been passionate about his work designing small molecules that target protein-protein interactions in cells for over a decade. Using an approach called structure-based rational drug design, he previously developed potential therapeutic candidate compounds for treatment-resistant breast cancer and for prostate cancer.

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