Summary: The protein Arginase-2 works through mitochondria to reduce inflammation. The findings could lead to new treatments for diseases associated with neuroinflammation, including multiple sclerosis and rheumatoid arthritis.
Source: RCSI
RCSI researchers have discovered a new way to ‘put the brakes’ on excessive inflammation by regulating a type of white blood cell that is critical for our immune system.
“An exciting outcome of this research is that it definitively shows the critical protective element at chromosome ends is the telomere DNA loop,” said Associate Professor Cesare.
“This likely explains why telomere length regulates ageing; cells must need long enough telomeres to make the DNA loops and this becomes difficult as cells age.”
Telomeres are the protective caps at chromosome ends. In adult cells, telomeres shorten each time a cell divides and this contributes to ageing and cancer. Pluripotent stem cells, however, are specialised cells that exist in the earliest days of development. These pluripotent cells do not age and have the ability to turn into any type of adult cell.
The surprise finding, published today in Nature, shows that telomeres in pluripotent stem cells are protected very differently than telomeres in adult tissues.
The Partei für Gesundheitsforschung (German Party for Health Research) demands, that the state should invest about 5 billion Euro per year additionally into biomedical research to hasten the development of effective medicine against the diseases of old age.
Here is our election program in German: https://parteifuergesundheitsforschung.de/wahlprogramm-der-p…erttemberg.
Please also consider donating money to the party, so that we can participate in more future elections. To participate in this years federal election in 12 states we would need e.g. at least about 50.000 Euro and unfortunately the party has almost no money at the moment. Election campaigns are a very good way to do advocacy for our cause and we can reach a lot of people this way, that we otherwise wouldn’t reach. Donating details: https://parteifuergesundheitsforschung.de/donate.
Individuals who had COVID are experiencing fatigue, shortness of breath, headaches, memory loss, heart palpations, they can’t think clearly…, more time will tell us the affects of being a COVID-19 victim.
“I really am disabled now, so it really does take a toll.”
Integrated circuits, brain sciences, genetics and biotechnology, clinical medicine and health care, and deep Earth, sea, space and polar exploration were named as the other five sectors that will be given priority in terms of funding and resources, according to a draft of the government’s 14th five-year plan for 2021–25, and its vision through 2035.
‘Basic research is the wellspring of scientific and technological innovation, so we’ll boost spending in this area by a considerable sum,’ Premier Li Keqiang says.
Studio Roosegaarde has built a UV light that can be installed in public spaces, allowing people to meet with less fear of contracting Covid-19.
A pregnant woman with suspected COVID-19 was rushed by ambulance to Skåne University Hospital, in Malmo, Sweden, suffering from sudden severe abdominal pain. The doctors noticed that the unborn infant had an abnormally low heart rate, which can be a sign that the baby is not getting enough oxygen.
The doctors performed an emergency caesarean section and delivered the baby within minutes. Blood tests from the baby confirmed it had severely low oxygen, and throat swabs showed that both mother and baby were suffering from COVID.
Using throat swabs from the mother and the newborn, the genome of the virus was sequenced to confirm the possibility that the infant had been infected with COVID while still in the womb.
All of the F.D.A.-approved vaccines offer strong protection against Covid-19, and assessing their efficacy isn’t as simple as a head-to-head comparison.
