Lifeboat Foundation

Vanderbilt researchers have developed a new nanoparticle that can more get drugs inside cells to boost the immune system and fight diseases such as cancer.

The research is led by John Wilson, associate professor of chemical and biomolecular engineering and biomedical engineering, as well as a corresponding author on the paper about the research that was recently published in the journal Nanoscale.

Wilson, who is Principal Investigator of the Immunoengineering Lab at Vanderbilt and a Chancellor Faculty Fellow, and his team created a polymeric nanoparticle that can penetrate cell membranes and get drugs into the cytosol—or liquid—inside cells.

Evo is a long-context biological foundation model that generalizes across the fundamental languages of biology: DNA, RNA, and proteins.

Introducing Evo, a biological foundation model that generalizes across the fundamental languages of biology: DNA, RNA and proteins. Evo is capable of both prediction tasks, and generative design from molecular to whole genome scale.

We are all ultimately overtaken by age, yet for some people, the correct genes can make the journey into old age rather slow.

Italian researchers made a unique discovery regarding people who survive well into their 90s and beyond a few years ago: they frequently possess a variant of the gene BPIFB4 that guards against cardiovascular disease and maintains the heart in excellent condition for a longer period of time.

It’s not often you encounter a device that looks like it came straight out of a movie set. But Lenovo’s Project Crystal, supposedly the world’s first laptop with a transparent microLED display, is an example of sci-fi come to life.

Currently there are no plans to turn Project Crystal into a retail product. Instead Lenovo’s latest concept device was commissioned by its ThinkPad division to explore the potential of transparent microLED panels and AI integration. The most obvious use case would be sharing info somewhere, like a doctor’s office or a hotel desk. Instead of needing to flip a screen around, you could simply reverse the display via software, allowing anyone on the other side to see it while getting an in-depth explanation.

There’s some relief for people with food severe allergies. A study published in the New England Journal of Medicine reports the drug Xolair allows people with allergies to tolerate higher doses of allergenic foods before developing a reaction after accidental exposure. Geoff Bennett discussed more with the study’s principal investigator, Dr. Robert Wood of the Johns Hopkins Children’s Center.

Notice: Transcripts are machine and human generated and lightly edited for accuracy. They may contain errors.

A new study suggests abdominal fat could impact brain health and cognition among people with a high risk of developing Alzheimer’s disease. Researchers found that middle-aged males at risk for Alzheimer’s who had higher amounts of pancreatic fat had lower cognition and brain volumes.

Researchers in China have reported the first large-scale study characterizing the proteomics and phosphoproteomics of small cell lung cancer (SCLC) clinical cohorts, providing a comprehensive picture of the proteogenomics landscape of SCLC.

The team is led by Prof. Zhang Peng from Shanghai Pulmonary Hospital of the Tongji University, Prof. Zhou Hu from Shanghai Institute of Materia Medica of the Chinese Academy of Sciences (CAS), and Prof. Gao Daming and Prof. Ji Hongbin from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of CAS.

This study, published in Cell, reveals the molecular features of SCLC and proposed new molecular subtypes and targeted personalized treatment strategies, and laying a solid foundation for a better understanding of the underlying mechanisms and improvement of clinical therapeutic strategies for SCLC.

New study links dopamine and serotonin changes in a brain region to social perception and decision-making regarding offer acceptance.

Scientists unravel dopamine-serotonin dynamics in first-in-humans study, unveiling social decision-making during awake surgery in Parkinson’s patients’ tracking economic exchange.

After a decade of obscurity, the technology is being used to track people’s movements.

Over a decade ago, Neal Patwari lay in a hospital bed, carefully timing his breathing.