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Researchers built a 3D model and tested it on young mice who were not yet capable of producing sperm – and after 5–7 weeks, sperm cells in the process of developing were discovered in the model, marking the success of the experiment.

“This system may also serve as an innovative platform for examining the effect of drugs and toxins on male fertility” Prof. Mahmoud Huleihel, BGU’s Faculty of Health Sciences

“This study opens up a new horizon in the process of creating sperm cells in a culture,” says study co-author Prof. Mahmoud Huleihel from BGU’s Faculty of Health Sciences. “It enables the implementation of microfluidic-based technologies in future therapeutic strategies for infertile men and in the preservation of fertility for children undergoing aggressive chemotherapy/radiotherapy treatments that may impair their fertility in puberty.”

“Ultrasonic frequencies are already being used in destructive procedures like laser ablation of tissues and tumours,” said Prof. Muthukumaran Packirisamy, who led the study along with Dr. Mohsen Habibi and PhD student Shervin Foroughi. “We wanted to use them to create something.”

For instance, utilizing the technique, aircraft mechanics could conceivably 3D-print repairs onto internal components, without opening the plane’s fuselage. It’s even possible that implants could be 3D printed within a patient’s body, without the need for surgery.

Besides the PDMS resin, the scientists have also successfully used DSP to print objects made of ceramic material. They now plan on experimenting with polymer-metal composites, followed by pure metal.

3D printing typically involves depositing layers of molten plastic, laser-melting powdered metal, or using UV light to harden gelatinous resin. A new technique takes yet another approach, however, by utilizing sound waves.

Observer, backup youthful copy, playing the right piano notes, quantum states oh my.


Dr David Sinclair explain about through his lab experiments, why he thinks there is an observer/backup copy for our youthfulness and what are the possible identities he can think of in this clip.

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Alzheimer’s disease has long thwarted our best efforts to pinpoint its underlying causes. Now, a new study in mice suggests that ‘poisonous flowers’ bulging with cellular debris could be the root source of one hallmark of the wretched disease and a beautifully sinister sign of a failing waste disposal system inside damaged brain cells.

The study, led by neuroscientist Ju-Hyun Lee of New York University (NYU) Langone, challenges the long-standing idea that the build-up of a protein called amyloid-beta between neurons is a crucial first step in Alzheimer’s disease, the most common form of dementia.

Instead, it suggests that damage to neurons may take root inside cells well before amyloid plaques fully form and clump together in the brain, a finding which could provide new therapeutic possibilities.

https://www.kickstarter.com/projects/2125914059/revopoint-mi…m-precison Designers, architects, engineers, we’re all collectively known as creators. The Revopoint MINI handheld 3D scanner just amplifies our creating (or rather re-creating) abilities. Designed to be about the same size as a podcasting microphone (with the tripod and all), Revopoint MINI is an industrial-grade handheld 3D scanner with a staggering precision of 0.02mm. It uses a Class 1 Blue Light that lends it its high accuracy, while still allowing it to be safe on the skin. Just hold it against the object you want to scan and wave it around and like magic, the Revopoint MINI gives you a high-accuracy 3D model, complete with tolerances, textures, and even color information. This makes it perfect for a wide degree of applications, from 3D modeling and animation to medical design, automotive design, jewelry design, even archaeology.

New findings were published in the New England Journal of Medicine on Sunday that found all rectal cancer patients given a certain bill were cancer-free.

The New York Times reported the findings, noting that the sample size was incredibly small, with just 18 people but the results were unbelievable.

“I believe this is the first time this has happened in the history of cancer,” said Dr. Luis A. Diaz Jr. of Memorial Sloan Kettering Cancer Center.

Scientists at the Foundation for Applied Molecular Evolution announced today that ribonucleic acid (RNA), an analog of DNA that was likely the first genetic material for life, spontaneously forms on basalt lava glass. Such glass was abundant on Earth 4.35 billion years ago. Similar basalts of this antiquity survive on Mars today.


More information:

Craig A. Jerome et al, Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses, Astrobiology (2022). DOI: 10.1089/ast.2022.

Hyo-Joong Kim et al, Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.