Treating fetuses for the enzyme deficiency might prevent early disease progression.
Category: biotech/medical – Page 1,117
Parents and medical providers are being called on to be careful with prescription cough medication as overdoses among children are on the rise.
Calls to poison control centers in the United States reporting the ingestion of prescription cough medicine by children rose by 158% between 2010 and 2018, according to a study published Tuesday by the Food and Drug Administration.
The study, published in the journal Pediatrics, found that pediatric poisonings involving the drug benzonatate, sold under the brand name Tessalon, have increased each year.
Can we measure empathy?
๐๐ฆ๐ฉ๐๐ญ๐ก๐ฒ ๐๐ฌ๐ญ๐ข๐ฆ๐๐ญ๐๐ ๐๐ฌ๐ข๐ง๐ ๐๐ข๐ง๐ ๐ฅ๐-๐๐๐ฅ๐ฅ ๐๐๐๐จ๐ซ๐๐ข๐ง๐ ๐ฌ ๐ข๐ง ๐๐ฎ๐ฆ๐๐ง ๐๐ซ๐๐ข๐ง
๐ผ ๐จ๐ฉ๐ช๐๐ฎ ๐๐ฃ ๐๐๐๐๐ ๐๐ฃ๐๐ก๐ฎ๐ฏ๐๐ ๐ฉ๐๐ ๐๐ค๐ฃ๐ฉ๐ง๐๐๐ช๐ฉ๐๐ค๐ฃ ๐ค๐ ๐ฉ๐๐ ๐๐ฃ๐จ๐ช๐ก๐ ๐๐ฃ ๐ค๐ช๐ง ๐๐๐๐ก๐๐ฉ๐ฎ ๐ฉ๐ค ๐ช๐ฃ๐๐๐ง๐จ๐ฉ๐๐ฃ๐ ๐ฉ๐๐ ๐ฅ๐๐๐ฃ ๐ค๐ ๐ค๐ฉ๐๐๐ง๐จ ๐๐ฎ ๐ง๐๐๐ค๐ง๐๐๐ฃ๐ ๐๐ง๐ค๐ข ๐๐ก๐๐๐ฉ๐ง๐ค๐๐๐จ ๐๐ข๐๐๐๐๐๐ ๐๐ฃ ๐ฉ๐๐ ๐๐ช๐ข๐๐ฃ ๐๐ง๐๐๐ฃ ๐ฉ๐๐๐ฉ ๐ข๐๐๐จ๐ช๐ง๐๐ ๐ฃ๐๐ช๐ง๐ค๐ฃ๐๐ก ๐๐๐ฉ๐๐ซ๐๐ฉ๐ฎ ๐๐ฃ ๐๐ฃ๐๐๐ซ๐๐๐ช๐๐ก ๐๐๐ก๐ก๐จ ๐๐ฃ ๐๐ฅ๐๐ก๐๐ฅ๐จ๐ฎ ๐ฅ๐๐ฉ๐๐๐ฃ๐ฉ๐จ ๐๐จ ๐ฉ๐๐๐ฎ ๐ซ๐๐๐ฌ๐๐ ๐จ๐๐ค๐ง๐ฉ ๐ข๐ค๐ซ๐๐๐จ ๐ค๐ ๐๐ฃ ๐๐๐ฉ๐ง๐๐จ๐จ ๐๐ฃ ๐ฅ๐๐๐ฃ. ๐๐๐ ๐จ๐ฉ๐ช๐๐ฎ ๐๐ข๐ฅ๐ง๐ค๐ซ๐๐จ ๐ค๐ช๐ง ๐ช๐ฃ๐๐๐ง๐จ๐ฉ๐๐ฃ๐๐๐ฃ๐ ๐ค๐ ๐ฉ๐๐ ๐๐ฃ๐๐๐ง๐๐ฃ๐ฉ ๐๐๐๐๐๐ง๐๐ฃ๐๐๐จ ๐๐ฃ ๐ฅ๐๐ค๐ฅ๐ก๐โ๐จ ๐๐๐๐ก๐๐ฉ๐ฎ ๐ฉ๐ค ๐๐ข๐ฅ๐๐ฉ๐๐๐ฏ๐ ๐๐ฃ๐ ๐ง๐๐๐๐ฉ ๐ฉ๐ค ๐ฉ๐๐ ๐ฅ๐๐๐ฃ ๐ค๐ ๐ค๐ฉ๐๐๐ง๐จ, ๐๐จ ๐ฌ๐๐ก๐ก ๐๐จ ๐ฅ๐ค๐ฉ๐๐ฃ๐ฉ๐๐๐ก ๐ข๐๐๐๐๐ฃ๐๐จ๐ข๐จ ๐๐ค๐ง ๐ฉ๐๐ ๐ก๐๐๐ ๐ค๐ ๐๐ข๐ฅ๐๐ฉ๐๐ฎ ๐๐ฃ ๐๐๐ง๐ฉ๐๐๐ฃ ๐ฃ๐๐ช๐ง๐ค๐ฅ๐จ๐ฎ๐๐๐๐๐ฉ๐ง๐๐ ๐๐ค๐ฃ๐๐๐ฉ๐๐ค๐ฃ๐จ.
Using intracranial electroencephalographic (iEEG) recordings and single-cell recordings from the human insulae in patients with epilepsy who have electrodes embedded in their brains, scientists have analyzed the contribution of the insula in our ability to understand the pain of others. The study improves our understanding of the inherent differences in peopleโs ability to empathize and react to the pain of others, as well as potential mechanisms for the lack of empathy in certain neuropsychiatric conditions.
This is primarily about Rejuvant or AKG trials. When they first reported an 8 year age difference I did not truly believe it as that would mean I could take it, de-age, then age a bit, then just take it again. The tests however are ongoing and will feature people who are biologically older than their calendar age. There is also mention of 110 drugs/supplements that do โsomethingโ to mice. That would be quite a stack to take.
Dr Brian Kennedy presents potential interventions for extend our healthspan. Among them, Rejuvant โ a CaAKG supplement which contain calcium + alpha-ketoglutarate shows better response for people who has biological age older than chronological age.
The first human trial of Rejuvant to reverse human biological age by 8 years in 7 month.
Rejuvantยฎ, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660611/
Dr. Brian Kennedy is internationally recognized for his research in the basic biology of aging and as a visionary committed to translating research discoveries into new ways of delaying, detecting, and preventing human aging and associated diseases. He is a Professor in the Departments of Biochemistry and Physiology at National University Singapore and Director of the Centre for Healthy Ageing in the National University Health System. From 2010 to 2016 he was the President and CEO of the Buck Institute for Research on Aging. Currently, he remains as a Professor at the Institute. Dr. Kennedy also has an adjunct appointment at the USC Davis School of Gerontology. Dr. Kennedy is also actively involved Biotechnology companies, serving in consulting and Board capacities, as well as Scientific Director of Affirmativ Health. Dr. Kennedy also serves as a Co-Editor-In-Chief at Aging Cell.
This included โevaluating lifeโ, such as seeing memories and assessing how they had treated others during their time alive.
Others felt like they were โheading to a destinationโ or were even aware that CPR was being performed.
Dr Sam Parnia, study author and a critical care expert from New York medical centre NYU Langone Health, said patients can also be aware of activities in intensive care after CPR and hear medics treating them.
Summary: Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimerโs.
Source: University of Bath.
A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at Kingโs College London and the University of Bath in the UK.
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Oregon State University scientists have invented a way to make magnetic nanoparticles that get hotter than any previous nanoparticle, improving their cancer fighting ability.
Faculty from the OSU College of Pharmacy spearheaded a collaboration that developed an advanced thermal decomposition method for producing nanoparticles able to reach temperatures in cancer lesions of up to 50 degrees Celsius, or 122 degrees Fahrenheit, when exposed to an alternating magnetic field.
Findings of the preclinical study led by Oleh Taratula and Olena Taratula were published today in the journal Small Methods.
Last year, MIT developed an AI/ML algorithm capable of learning and adapting to new information while on the job, not just during its initial training phase. These โliquidโ neural networks (in the Bruce Lee sense) literally play 4D chess โ their models requiring time-series data to operate โ which makes them ideal for use in time-sensitive tasks like pacemaker monitoring, weather forecasting, investment forecasting, or autonomous vehicle navigation. But, the problem is that data throughput has become a bottleneck, and scaling these systems has become prohibitively expensive, computationally speaking.
On Tuesday, MIT researchers announced that they have devised a solution to that restriction, not by widening the data pipeline but by solving a differential equation that has stumped mathematicians since 1907. Specifically, the team solved, โthe differential equation behind the interaction of two neurons through synapsesโฆ to unlock a new type of fast and efficient artificial intelligence algorithms.โ
โThe new machine learning models we call โCfCโsโ [closed-form Continuous-time] replace the differential equation defining the computation of the neuron with a closed form approximation, preserving the beautiful properties of liquid networks without the need for numerical integration,โ MIT professor and CSAIL Director Daniela Rus said in a Tuesday press statement. โCfC models are causal, compact, explainable, and efficient to train and predict. They open the way to trustworthy machine learning for safety-critical applications.โ
Two Fathers One Egg
Posted in biotech/medical, sex
What will it take for a same-sex coupleโtwo males or two femalesโto be able to produce a biological child by combining their genomes in the same way that male-female couples do? Just to be clear, weโre not talking about adopting. Nor do we mean one mate fertilizes a donor egg or is fertilized with donated sperm. Those things have long existed. We mean you take two women or two men and make a baby.
And theyโve already done it with two male mice.