Lifeboat Foundation: Safeguarding Humanity
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Category: bioengineering – Page 8

Tissue engineering utilizes 3D printing and bioink to grow human cells on scaffolds, creating replacements for damaged tissues like skin, cartilage, and even organs. A team of researchers led by Professor Insup Noh from Seoul National University of Science and Technology, Republic of Korea, has developed a bioink using nanocellulose derived from Kombucha SCOBY (Symbiotic Culture of Bacteria and Yeast) as the scaffold material.

The biomaterial offers a sustainable alternative to conventional options, and it can be loaded onto a hand-held “Biowork” biopen, also developed by the same team. The digital biopen allows the precise application of bioink to damaged defected areas, such as irregular cartilage and large skin wounds, paving the way for more personalized and effective in vivo tissue repair, eliminating the need for in vitro processes.

This paper was published in the International Journal of Biological Macromolecules on 1 December 2024.

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Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle’s docking system and its counterpart on the station. Thanks to international standards, these mechanisms are universally compatible, ensuring astronauts and cargo can safely and seamlessly enter the station.

A similar challenge arises at the microscopic level when (LNPs)—the revolutionary drug vehicles behind the COVID-19 vaccines—attempt to deliver mRNA to cells. Optimizing the design and delivery of LNPs can greatly enhance their ability to deliver mRNA successfully, empowering cells with the disease-fighting instructions needed to transform medicine.

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This week, The Circuit explores the cutting-edge technology of artificial wombs! Discover how engineers and scientists are working to save premature babies and even endangered species.
In this episode, we look at:

• The development of artificial womb technology for human preemie babies.
• How the Okinawa Churaumi Aquarium is using artificial wombs to save.
shark embryos.
• How bioengineers were able to grow a premature lamb in a biobag.

Artificial wombs represent a fascinating intersection of biology and engineering.

What are YOUR thoughts on the artificial womb? Amazing or frightening?

#ArtificialWomb #Preemies #SharkConservation #Biology #Engineering #NeonatalCare #MedTech #TheCircuit #Pregnancy #Doctors #Hospital #Healthcare

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Dive into the captivating realm of Biopunk Science Fiction in our latest video! 🌱 Discover what Biopunk is, from genetic engineering to human augmentation, and explore the ethical dilemmas it presents in our modern world. We’ll discuss its evolution through literature and film, touching on iconic works like \.

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Biopunk androids replicants.

What happens when humans begin combining biology with technology, harnessing the power to recode life itself.

What does the future of biotechnology and genetic engineering look like? How will humans program biology to create organ farm technology and bio-robots. And what happens when companies begin investing in advanced bio-printing, artificial wombs, and cybernetic prosthetic limbs.

Other topic include: bioengineered food and farming, bio-printing in space, new age living bioarchitecture (eco concrete inspired by coral reefs), bioengineered bioluminescence, cyberpunks and biopunks who experiment underground — creating new age food and pets, the future of bionics, corporations owning bionic limbs, the multi-trillion dollar industry of bio-robots, and bioengineered humans with super powers (Neo-Humans).

As well as the future of biomedical engineering, biochemistry, and biodiversity.

Continue reading “BIOTECHNOLOGY in the Future: 2050 (Artificial Biology)” | >

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice. Their work establishes a next-generation gene-editing tool that enhances genetic manipulation for cancer and medical research in a preclinical model.

The study, “Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening,” was published in Nature Communications.

“This is the first time Cas12a has been used in preclinical models, which will greatly advance our genome engineering capabilities,” said co-author Eddie La Marca, PhD, a postdoctoral researcher at the Olivia Newton-John Cancer Research Institute (ONJCRI) in Australia.

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The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Researchers from the Wellcome Sanger Institute, Imperial College London, Harvard University in the US and their collaborators used CRISPR prime editing to create multiple versions of human genomes in cell lines, each with different structural changes. Using genome sequencing, they were able to analyze the genetic effects of these structural variations on .

The research, published in Science, shows that as long as essential genes remain intact, our genomes can tolerate significant structural changes, including large deletions of the genetic code. The work opens the door to studying and predicting the role of structural variation in disease.

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We often discuss cybernetic, genetic engineering, artificial intelligence, and hybrids of them, but what truly is synthetic life? And what is it like?

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Credits:
Synthetic Life.
Science & Futurism with Isaac Arthur.
Episode 333a, March 13, 2022
Written, Produced & Narrated by Isaac Arthur.

Editors:
David McFarlane.
Jason Burbank.
Jerry Guern.

Cover Art:
Jakub Grygier https://www.artstation.com/jakub_grygier.

Music Courtesy of Epidemic Sound http://epidemicsound.com/creator

Continue reading “Creating Synthetic Life” | >

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells. This vital function is often disrupted in cancer patients undergoing chemotherapy or radiation, which can damage the marrow and lead to dangerously low white cell counts, leaving patients vulnerable to infection.

Now, researchers at the University of Pennsylvania School of Engineering and Applied Science (Penn Engineering), Perelman School of Medicine (PSOM) and the Children’s Hospital of Philadelphia (CHOP) have developed a platform that emulates human marrow’s native environment. This breakthrough addresses a critical need in medical science, as animal studies often fail to fully replicate the complexities of human marrow.

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